Browsing Toxins By Category
Displaying toxin 2576 - 2600 of 3678 in total
T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
---|---|---|---|---|---|
T3D3977 | Methylparaben 99-76-3 | C8H8O3 152.147 g/mol |
| Not Available Number of Targets: 8 | |
T3D2786 | Methylphenidate 113-45-1 | C14H19NO2 233.306 g/mol |
| Methylphenidate blocks dopamine uptake in central adrenergic neurons by blocking dopamine transport or carrier proteins. Methylphenidate acts at the brain stem arousal...more Number of Targets: 3 | |
T3D4748 | Methyltestosterone 58-18-4 | C20H30O2 302.451 g/mol |
| The effects of testosterone in humans and other vertebrates occur by way of two main mechanisms: by activation of the androgen receptor (directly or as DHT), and by co...more Number of Targets: 4 | |
T3D1339 | Methyltriethyl lead 1762-28-3 | C7H18Pb 309.400 g/mol |
| Lead mimics other biologically important metals, such as zinc, calcium, and iron, competing as cofactors for many of their respective enzymatic reactions. For example,...more Number of Targets: 29 | |
T3D2987 | Methyprylon 125-64-4 | C10H17NO2 183.248 g/mol |
| Methyprylon binds at a distinct binding site associated with a Cl- ionopore at the GABAA receptor, increasing the duration of time for which the Cl- ionopore is open. ...more Number of Targets: 2 | |
T3D2726 | Methysergide 361-37-5 | C21H27N3O2 353.458 g/mol |
| Ergoline alkaloids have been shown to have the significant affinity towards the 5-HT1 and 5-HT2 serotonin receptors, D1 and D2 dopamine receptors, and alpha-adrenergic...more Number of Targets: 11 | |
T3D2755 | Metixene 4969-02-2 | C20H23NS 309.468 g/mol |
| Parkinsonism is thought to result from an imbalance between the excitatory (cholinergic) and inhibitory (dopaminergic) systems in the corpus striatum. The mechanism of...more Number of Targets: 5 | |
T3D1089 | Metolachlor 51218-45-2 | C15H22ClNO2 283.794 g/mol |
| Metolachlor acts by inhibition of elongases and of the geranylgeranyl pyrophosphate (GGPP) cyclases, which are part of the gibberellin pathway. It also binds to nAChRs...more Number of Targets: 26 | |
T3D0985 | Metolcarb 1129-41-5 | C9H11NO2 165.189 g/mol |
| Metolcarb is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable complexes with chlolinesterases by carbamoylation of the active sites ...more Number of Targets: 2 | |
T3D3882 | Metribuzin 21087-64-9 | C8H14N4OS 214.288 g/mol |
| Not Available Number of Targets: 11 | |
T3D4703 | Metronidazole 443-48-1 | C6H9N3O3 171.154 g/mol |
| Metronidazole is a prodrug. Unionized metronidazole is selective for anaerobic bacteria due to their ability to intracellularly reduce metronidazole to its active form...more Number of Targets: 1 | |
T3D3883 | Metsulfuron-methyl 74223-64-6 | C14H15N5O6S 381.364 g/mol |
| Not Available Number of Targets: 2 | |
T3D3884 | Mevinphos 7786-34-7 | C7H13O6P 224.148 g/mol |
| Mevinphos is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholinester...more Number of Targets: 10 | |
T3D0986 | Mexacarbate 315-18-4 | C12H18N2O2 222.284 g/mol |
| Mexacarbate is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable complexes with chlolinesterases by carbamoylation of the active site...more Number of Targets: 2 | |
T3D4649 | Mexazolam 31868-18-5 | C18H16Cl2N2O2 363.238 g/mol |
| Benzodiazepines bind nonspecifically to benzodiazepine receptors BNZ1, which mediates sleep, and BNZ2, which affects affects muscle relaxation, anticonvulsant activity...more Number of Targets: 18 | |
T3D3885 | MGK 113-48-4 | C17H25NO2 275.386 g/mol |
| Not Available Number of Targets: 6 | |
T3D2988 | Miconazole 22916-47-8 | C18H14Cl4N2O 416.129 g/mol |
| Miconazole interacts with 14-α demethylase, a cytochrome P-450 enzyme necessary to convert lanosterol to ergosterol. As ergosterol is an essential component of the fun...more Number of Targets: 17 | |
T3D3611 | Microcystin-LF 154037-70-4 | C52H71N7O12 986.160 g/mol |
| The site of action of microcystins is the hepatocyte, the commonest cell type in the liver. They act by disrupting the cytoskeleton, the adaptable protein framework th...more Number of Targets: 23 | |
T3D3613 | Microcystin-LL 154037-67-9 | C49H73N7O12 952.144 g/mol |
| The site of action of microcystins is the hepatocyte, the commonest cell type in the liver. They act by disrupting the cytoskeleton, the adaptable protein framework th...more Number of Targets: 23 | |
T3D3602 | Microcystin-LR 101043-37-2 | Not Available Not Available |
| The site of action of microcystins is the hepatocyte, the commonest cell type in the liver. They act by disrupting the cytoskeleton, the adaptable protein framework th...more Number of Targets: 24 | |
T3D3614 | Microcystin-LW 157622-02-1 | C54H72N8O12 1025.196 g/mol |
| The site of action of microcystins is the hepatocyte, the commonest cell type in the liver. They act by disrupting the cytoskeleton, the adaptable protein framework th...more Number of Targets: 23 | |
T3D3615 | Microcystin-LY 123304-10-9 | C52H71N7O13 1002.159 g/mol |
| The site of action of microcystins is the hepatocyte, the commonest cell type in the liver. They act by disrupting the cytoskeleton, the adaptable protein framework th...more Number of Targets: 23 | |
T3D3609 | Microcystin-RR 111755-37-4 | C49H75N13O12 1038.200 g/mol |
| The site of action of microcystins is the hepatocyte, the commonest cell type in the liver. They act by disrupting the cytoskeleton, the adaptable protein framework th...more Number of Targets: 23 | |
T3D3608 | Microcystin-YR 101064-48-6 | C52H72N10O13 1045.187 g/mol |
| The site of action of microcystins is the hepatocyte, the commonest cell type in the liver. They act by disrupting the cytoskeleton, the adaptable protein framework th...more Number of Targets: 23 | |
T3D2859 | Midazolam 59467-70-8 | C18H13ClFN3 325.767 g/mol |
| It is thought that the actions of benzodiazepines such as midazolam are mediated through the inhibitory neurotransmitter gamma-aminobutyric acid (GABA), which is one o...more Number of Targets: 23 |