NameDNA-directed RNA polymerases I and III subunit RPAC2
Synonyms
  • AC19
  • DNA-directed RNA polymerase I subunit D
  • hRPA19
  • RNA polymerase I 16 kDa subunit
  • RNA polymerases I and III subunit AC2
  • RPA16
  • RPC16
Gene NamePOLR1D
OrganismHuman
Amino acid sequence
>lcl|BSEQ0009604|DNA-directed RNA polymerases I and III subunit RPAC2
MEEDQELERKISGLKTSMAEGERKTALEMVQAAGTDRHCVTFVLHEEDHTLGNSLRYMIM
KNPEVEFCGYTTTHPSESKINLRIQTRGTLPAVEPFQRGLNELMNVCQHVLDKFEASIKD
YKDQKASRNESTF
Number of residues133
Molecular Weight15237.11
Theoretical pINot Available
GO Classification
Functions
  • DNA-directed RNA polymerase activity
  • DNA binding
Processes
  • transcription initiation from RNA polymerase I promoter
  • gene expression
  • innate immune response
  • negative regulation of gene expression, epigenetic
  • regulation of gene expression, epigenetic
  • positive regulation of type I interferon production
  • termination of RNA polymerase I transcription
  • termination of RNA polymerase III transcription
  • transcription elongation from RNA polymerase I promoter
  • transcription elongation from RNA polymerase III promoter
  • transcription from RNA polymerase I promoter
  • transcription from RNA polymerase III promoter
Components
  • cytosol
  • nucleoplasm
  • DNA-directed RNA polymerase I complex
  • DNA-directed RNA polymerase III complex
General FunctionDna-directed rna polymerase activity
Specific FunctionDNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common core component of RNA polymerases I and III which synthesize ribosomal RNA precursors and small RNAs, such as 5S rRNA and tRNAs, respectively.
Pfam Domain FunctionNot Available
Transmembrane RegionsNot Available
GenBank Protein IDNot Available
UniProtKB IDQ9Y2S0
UniProtKB Entry NameRPAC2_HUMAN
Cellular LocationNucleus
Gene sequence
>lcl|BSEQ0013663|DNA-directed RNA polymerases I and III subunit RPAC2 (POLR1D)
ATGGGACCCATGGGTTGGATGAAGTGTCCTCTTGCTAGCACCAATAAAAGATTTCTAATT
AACACAATTAAAAACACATTGCCCTCTCATAAAGAGCAAGACCATGAACAAAAAGAGGGC
GATAAGGAACCAGCGAAGAGCCAGGCCCAGAAAGAAGAAAACCCGAAGAAACACAGAAGC
CATCCTTACAAGCACAGCTTCCGCGCTCGAGGTTCCGCCAGTTACTCCCCGCCACGAAAG
CGGAGCAGCCAGGACAAGTACGAAAAGCGGTCCAACCGGCGGTGA
GenBank Gene IDNot Available
GeneCard IDNot Available
GenAtlas IDNot Available
HGNC IDHGNC:20422
Chromosome Location13
LocusNot Available
References
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