Glutathione S-transferase kappa 1

NameGlutathione S-transferase kappa 1
Synonyms
  • 2.5.1.18
  • Glutathione S-transferase subunit 13
  • GST 13-13
  • GST class-kappa
  • GSTK1-1
  • hGSTK1
Gene NameGSTK1
OrganismHuman
Amino acid sequence
>lcl|BSEQ0037081|Glutathione S-transferase kappa 1
MGPLPRTVELFYDVLSPYSWLGFEILCRYQNIWNINLQLRPSLITGIMKDSGNKPPGLLP
RKGLYMANDLKLLRHHLQIPIHFPKDFLSVMLEKGSLSAMRFLTAVNLEHPEMLEKASRE
LWMRVWSRNEDITEPQSILAAAEKAGMSAEQAQGLLEKIATPKVKNQLKETTEAACRYGA
FGLPITVAHVDGQTHMLFGSDRMELLAHLLGEKWMGPIPPAVNARL
Number of residues226
Molecular Weight25496.625
Theoretical pI8.69
GO Classification
Functions
  • receptor binding
  • glutathione transferase activity
  • protein disulfide oxidoreductase activity
  • glutathione peroxidase activity
Processes
  • glutathione metabolic process
  • glutathione derivative biosynthetic process
  • epithelial cell differentiation
  • small molecule metabolic process
  • oxidation-reduction process
  • xenobiotic metabolic process
Components
  • intracellular
  • membrane
  • mitochondrial inner membrane
  • mitochondrial matrix
  • peroxisome
  • extracellular exosome
  • intracellular membrane-bounded organelle
General FunctionReceptor binding
Specific FunctionSignificant glutathione conjugating activity is found only with the model substrate, 1-chloro-2,4-dinitrobenzene (CDNB).
Pfam Domain Function
Transmembrane RegionsNot Available
GenBank Protein ID41351794
UniProtKB IDQ9Y2Q3
UniProtKB Entry NameGSTK1_HUMAN
Cellular LocationPeroxisome
Gene sequence
>lcl|BSEQ0016214|Glutathione S-transferase kappa 1 (GSTK1)
ATGGGGCCCCTGCCGCGCACCGTGGAGCTCTTCTATGACGTGCTGTCCCCCTACTCCTGG
CTGGGCTTCGAGATCCTGTGCCGGTATCAGAATATCTGGAACATCAACCTGCAGTTGCGG
CCCAGCCTCATAACAGGGATCATGAAAGACAGTGGAAACAAGCCTCCAGGTCTGCTTCCC
CGCAAAGGACTATACATGGCAAATGACTTAAAGCTCCTGAGACACCATCTCCAGATTCCC
ATCCACTTCCCCAAGGATTTCTTGTCTGTGATGCTTGAAAAAGGAAGTTTGTCTGCCATG
CGTTTCCTCACCGCCGTGAACTTGGAGCATCCAGAGATGCTGGAGAAAGCGTCCCGGGAG
CTGTGGATGCGCGTCTGGTCAAGGGTGAGTGTGGGGCTCTGGGAATCCTCTGGGAGGACC
TTGGATGACTTTCTGACCTTCCCCAGGCACGTTTTCAGGGTCATGATCCTGCCCCCGCCC
GGGGGATCTACTGTCCTCCCAGTCACACCCCTCTCCCCGCACCGCCTTCCTGCTGTCTTC
TCTTCTTCCCAGAATGAAGACATCACCGAGCCGCAGAGCATCCTGGCGGCTGCAGAGAAG
GCTGGTATGTCTGCAGAACAAGCCCAGGGACTTCTGGAAAAGATCGCAACGCCAAAGGTG
AAGAACCAGCTCAAGGAGACCACTGAGGCAGCCTGCAGATACGGAGCCTTTGGGCTGCCC
ATCACCGTGGCCCATGTGGATGGCCAAACCCACATGTTATTTGGCTCTGACCGGATGGAG
CTGCTGGCGCACCTGCTGGGAGAGAAGTGGATGGGCCCTATACCTCCAGCCGTGAATGCC
AGACTTTAA
GenBank Gene IDAY520571
GeneCard IDNot Available
GenAtlas IDGSTK1
HGNC IDHGNC:16906
Chromosome Location7
Locus-
References
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