NameEpididymis-specific alpha-mannosidase
Synonyms
  • 3.2.1.24
  • KIAA0935
  • Mannosidase alpha class 2B member 2
Gene NameMAN2B2
OrganismHuman
Amino acid sequence
>lcl|BSEQ0009607|Epididymis-specific alpha-mannosidase
MGQLCWLPLLAPLLLLRPPGVQSAGPIRAFVVPHSHMDVGWVYTVQESMRAYAANVYTSV
VEELARGQQRRFIAVEQEFFRLWWDGVASDQQKYQVRQLLEEGRLEFVIGGQVMHDEAVT
HLDDQILQLTEGHGFLYETFGIRPQFSWHVDPFGASATTPTLFALAGFNAHLGSRIDYDL
KAAMQEARGLQFVWRGSPSLSERQEIFTHIMDQYSYCTPSHIPFSNRSGFYWNGVAVFPK
PPQDGVYPNMSEPVTPANINLYAEALVANVKQRAAWFRTPHVLWPWGCDKQFFNASVQFA
NMDPLLDHINSHAAELGVSVQYATLGDYFRALHALNVTWRVRDHHDFLPYSTEPFQAWTG
FYTSRSSLKGLARRASALLYAGESMFTRYLWPAPRGHLDPTWALQQLQQLRWAVSEVQHH
DAITGTESPKVRDMYATHLASGMLGMRKLMASIVLDELQPQAPMAASSDAGPAGHFASVY
NPLAWTVTTIVTLTVGFPGVRVTDEAGHPVPSQIQNSTETPSAYDLLILTTIPGLSYRHY
NIRPTAGAQEGTQEPAATVASTLQFGRRLRRRTSHAGRYLVPVANDCYIVLLDQDTNLMH
SIWERQSNRTVRVTQEFLEYHVNGDVKQGPISDNYLFTPGKAAVPAWEAVEMEIVAGQLV
TEIRQYFYRNMTAQNYTYAIRSRLTHVPQGHDGELLCHRIEQEYQAGPLELNREAVLRTS
TNLNSQQVIYSDNNGYQMQRRPYVSYVNNSIARNYYPMVQSAFMEDGKSRLVLLSERAHG
ISSQGNGQVEVMLHRRLWNNFDWDLGYNLTLNDTSVVHPVLWLLLGSWSLTTALRQRSAL
ALQHRPVVLFGDLAGTAPKLPGPQQQEAVTLPPNLHLQILSIPGWRYSSNHTEHSQNLRK
GHRGEAQADLRRVLLRLYHLYEVGEDPVLSQPVTVNLEAVLQALGSVVAVEERSLTGTWD
LSMLHRWSWRTGPGRHRGDTTSPSRPPGGPIITVHPKEIRTFFIHFQQQ
Number of residues1009
Molecular Weight113978.29
Theoretical pINot Available
GO Classification
Functions
  • zinc ion binding
  • carbohydrate binding
  • alpha-mannosidase activity
Processes
  • protein deglycosylation
  • mannose metabolic process
Components
  • vacuolar membrane
  • extracellular exosome
General FunctionZinc ion binding
Specific FunctionNot Available
Pfam Domain Function
Transmembrane RegionsNot Available
GenBank Protein IDNot Available
UniProtKB IDQ9Y2E5
UniProtKB Entry NameMA2B2_HUMAN
Cellular LocationSecreted
Gene sequence
>lcl|BSEQ0013666|Epididymis-specific alpha-mannosidase (MAN2B2)
ATGGGGCAGCTGTGCTGGCTGCCGCTGCTGGCACCGCTCCTGTTGCTGCGACCGCCAGGG
GTCCAGTCCGCCGGCCCCATCCGGGCCTTCGTGGTGCCCCACAGCCACATGGACGTGGGC
TGGGTCTACACTGTGCAGGAAAGCATGCGGGCGTACGCCGCCAATGTCTACACCTCAGTG
GTGGAAGAGCTGGCCCGCGGCCAGCAGCGCCGGTTCATCGCTGTGGAGCAGGAGTTTTTC
CGGCTGTGGTGGGATGGCGTCGCCTCGGACCAGCAGAAATACCAGGTCCGCCAGCTCCTG
GAGGAAGGACGCCTGGAATTTGTCATCGGAGGCCAGGTCATGCATGACGAGGCTGTGACG
CACCTTGATGACCAGATCCTGCAGCTCACAGAAGGACACGGGTTTCTCTATGAAACATTT
GGGATCCGGCCACAGTTCTCCTGGCACGTTGACCCGTTTGGCGCCTCTGCCACGACGCCC
ACCCTATTTGCGCTGGCGGGCTTCAATGCCCACCTCGGCTCCCGGATCGACTACGACCTG
AAGGCAGCCATGCAGGAGGCCCGGGGGCTGCAGTTCGTGTGGCGAGGGTCCCCATCCCTC
TCAGAGCGGCAGGAAATCTTCACGCACATCATGGACCAGTACAGCTACTGCACCCCGTCC
CACATCCCTTTCTCCAACAGGTCAGGATTTTACTGGAATGGCGTGGCTGTCTTCCCCAAG
CCTCCCCAAGATGGGGTGTACCCCAACATGAGTGAGCCTGTCACCCCAGCCAACATCAAC
CTCTATGCCGAGCTCGGTGTCTCGGTGCAGTATGCCACGCTGGGCGACTACTTCCGTGCC
CTGCACGCTCTCAATGTCACCTGGCGTGTCCGCGACCACCACGACTTCCTGCCCTATTCC
ACAGAACCATTCCAGGCCTGGACGGGCTTCTACACGTCCCGCAGCTCACTGAAGGGGCTG
GCCCGGCGAGCCAGCGCCTTGTTGTATGCCGGGGAGTCCATGTTCACACGCTACCTGTGG
CCGGCCCCCCGTGGGCATCTGGACCCCACCTGGGCCCTGCAGCAGCTCCAGCAGCTTCGC
TGGGCCGTCTCCGAGGTCCAGCACCATGATGCCATCACTGGGACTGAGTCCCCCAAGGTG
AGAGACATGTACGCAACGCACCTGGCCTCGGGGATGCTGGGCATGCGCAAGCTGATGGCC
TCCATCGTCCTAGATGAGCTCCAGCCCCAGGCACCCATGGCGGCCAGCTCCGATGCAGGA
CCTGCAGGACATTTTGCCTCGGTCTACAACCCGCTGGCCTGGACGGTCACCACCATCGTC
ACCCTGACTGTTGGTTTCCCTGGAGTCCGCGTCACAGATGAGGCGGGCCACCCAGTGCCC
TCGCAGATCCAGAACTCAACAGAGACCCCATCTGCGTATGACCTGCTTATTCTGACCACA
ATCCCAGGCCTCAGTTACCGGCACTACAACATCAGACCCACTGCAGGGGCCCAAGAGGGC
ACCCAGGAGCCGGCTGCCACTGTGGCGAGCACCCTTCAATTTGGCCGCAGGCTGAGGAGA
CGCACCAGCCATGCGGGCAGGTACTTGGTGCCTGTGGCAAACGACTGCTACATTGTGCTG
CTCGACCAGGATACCAACCTGATGCACAGCATCTGGGAGAGACAGAGTAACCGAACGGTG
CGCGTGACCCAGGAATTCCTGGAGTACCACGTCAACGGGGATGTGAAACAGGGCCCCATT
TCCGATAACTACCTGTTCACACCGGGCAAGGCCGCGGTGCCTGCGTGGGAAGCTGTGGAA
ATGGAGATTGTGGCGGGACAGCTTGTGACTGAGATCCGGCAGTACTTCTACAGGAACATG
ACAGCACAGAATTACACGTATGCAATCCGCTCCCGGCTCACCCATGTGCCGCAGGGCCAT
GACGGGGAGCTGCTCTGCCACCGGATAGAGCAGGAGTACCAAGCCGGCCCCCTGGAGCTG
AACCGTGAGGCTGTCCTGAGGACCAGCACCAACCTAAACAGCCAGCAGGTCATCTACTCA
GACAACAACGGCTACCAGATGCAGCGGAGGCCCTACGTTTCCTATGTGAACAACAGCATC
GCCCGGAATTACTACCCCATGGTTCAGTCGGCCTTCATGGAGGATGGCAAAAGCAGGCTT
GTGTTGCTGTCGGAGCGGGCACATGGCATCTCCAGCCAAGGGAATGGGCAGGTGGAGGTC
ATGCTCCACCGGCGGCTGTGGAACAACTTCGACTGGGACCTGGGCTACAACCTCACGCTG
AACGACACCTCAGTCGTCCACCCAGTGCTCTGGCTTCTGCTGGGATCCTGGTCCCTCACC
ACTGCCCTGCGCCAGAGGAGCGCACTGGCGCTGCAGCACAGGCCCGTGGTGCTGTTCGGA
GACCTCGCTGGGACTGCGCCGAAGCTCCCAGGACCCCAGCAGCAAGAGGCCGTGACGCTG
CCCCCGAATCTTCACCTGCAGATCCTGAGCATCCCTGGCTGGCGCTACAGCTCCAACCAC
ACGGAGCACTCTCAGAATCTCCGGAAAGGCCATCGAGGGGAAGCCCAGGCTGACCTCCGC
CGTGTCCTGCTGCGGCTCTACCACCTGTATGAAGTGGGCGAGGACCCAGTCCTGTCTCAG
CCAGTGACAGTGAATCTGGAGGCTGTGCTGCAGGCGCTGGGGTCCGTGGTGGCAGTGGAG
GAGCGCTCGCTCACAGGGACCTGGGATTTGAGCATGCTGCACCGCTGGAGCTGGAGGACG
GGGCCTGGCCGCCACAGAGGTGACACCACCTCTCCCTCGAGGCCACCAGGAGGCCCCATC
ATCACCGTCCACCCAAAGGAAATCCGGACGTTCTTTATTCACTTTCAACAGCAGTGA
GenBank Gene IDNot Available
GeneCard IDNot Available
GenAtlas IDNot Available
HGNC IDHGNC:29623
Chromosome Location4
LocusNot Available
References
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