Voltage-dependent anion-selective channel protein 3

NameVoltage-dependent anion-selective channel protein 3
Synonyms
  • Outer mitochondrial membrane protein porin 3
  • VDAC-3
Gene NameVDAC3
OrganismHuman
Amino acid sequence
>lcl|BSEQ0004851|Voltage-dependent anion-selective channel protein 3
MCNTPTYCDLGKAAKDVFNKGYGFGMVKIDLKTKSCSGVEFSTSGHAYTDTGKASGNLET
KYKVCNYGLTFTQKWNTDNTLGTEISWENKLAEGLKLTLDTIFVPNTGKKSGKLKASYKR
DCFSVGSNVDIDFSGPTIYGWAVLAFEGWLAGYQMSFDTAKSKLSQNNFALGYKAADFQL
HTHVNDGTEFGGSIYQKVNEKIETSINLAWTAGSNNTRFGIAAKYMLDCRTSLSAKVNNA
SLIGLGYTQTLRPGVKLTLSALIDGKNFSAGGHKVGLGFELEA
Number of residues283
Molecular Weight30658.45
Theoretical pI8.9
GO Classification
Functions
  • porin activity
  • voltage-gated anion channel activity
  • nucleotide binding
Processes
  • adenine transport
  • regulation of anion transmembrane transport
  • regulation of cilium assembly
Components
  • mitochondrial outer membrane
  • extracellular exosome
  • pore complex
  • mitochondrion
  • nucleus
General FunctionVoltage-gated anion channel activity
Specific FunctionForms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules.
Pfam Domain Function
Transmembrane Regions26-35 39-47 54-64 69-76 80-89 95-104 111-120 123-130 137-145 150-158 163-175 178-185 189-198 202-211 218-227 231-238 242-251 254-263 273-282
GenBank Protein IDNot Available
UniProtKB IDQ9Y277
UniProtKB Entry NameVDAC3_HUMAN
Cellular LocationMitochondrion outer membrane
Gene sequence
>lcl|BSEQ0011768|Voltage-dependent anion-selective channel protein 3 (VDAC3)
ATGTGTAACACACCAACGTACTGTGACCTAGGAAAGGCTGCTAAGGATGTCTTCAACAAA
GGATATGGCTTTGGCATGGTCAAGATAGACCTGAAAACCAAGTCTTGTAGTGGAGTGATG
GAATTTTCTACTTCTGGTCATGCTTACACTGATACAGGGAAAGCATCAGGCAACCTAGAA
ACCAAATATAAGGTCTGTAACTATGGACTTACCTTCACCCAGAAATGGAACACAGACAAT
ACTCTAGGGACAGAAATCTCTTGGGAGAATAAGTTGGCTGAAGGGTTGAAACTGACTCTT
GATACCATATTTGTACCGAACACAGGAAAGAAGAGTGGGAAATTGAAGGCCTCCTATAAA
CGGGATTGTTTTAGTGTTGGCAGTAATGTTGATATAGATTTTTCTGGACCAACCATCTAT
GGCTGGGCTGTGTTGGCCTTCGAAGGGTGGCTTGCTGGCTATCAGATGAGTTTTGACACA
GCCAAATCCAAACTGTCACAGAATAATTTCGCCCTGGGTTACAAGGCTGCGGACTTCCAG
CTGCACACACATGTGAACGATGGCACTGAATTTGGAGGTTCTATCTACCAGAAGGTGAAT
GAGAAGATTGAAACATCCATAAACCTTGCTTGGACAGCTGGGAGTAACAACACCCGTTTT
GGCATTGCTGCTAAGTACATGCTGGATTGTAGAACTTCTCTCTCTGCTAAAGTAAATAAT
GCCAGCCTGATTGGACTGGGTTATACTCAGACCCTTCGACCAGGAGTCAAATTGACTTTA
TCAGCTTTAATCGATGGGAAGAACTTCAGTGCAGGAGGTCACAAGGTTGGCTTGGGATTT
GAACTGGAAGCTTAA
GenBank Gene IDU90943
GeneCard IDNot Available
GenAtlas IDVDAC3
HGNC IDHGNC:12674
Chromosome Location8
Locus8p11.2
References
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