NameGTP:AMP phosphotransferase AK3, mitochondrial
Synonyms
  • 2.7.4.10
  • Adenylate kinase 3
  • Adenylate kinase 3 alpha-like 1
  • AK 3
  • AK3L1
  • AK6
  • AKL3L
Gene NameAK3
OrganismHuman
Amino acid sequence
>lcl|BSEQ0009404|GTP:AMP phosphotransferase AK3, mitochondrial
MGASARLLRAVIMGAPGSGKGTVSSRITTHFELKHLSSGDLLRDNMLRGTEIGVLAKAFI
DQGKLIPDDVMTRLALHELKNLTQYSWLLDGFPRTLPQAEALDRAYQIDTVINLNVPFEV
IKQRLTARWIHPASGRVYNIEFNPPKTVGIDDLTGEPLIQREDDKPETVIKRLKAYEDQT
KPVLEYYQKKGVLETFSGTETNKIWPYVYAFLQTKVPQRSQKASVTP
Number of residues227
Molecular Weight25565.2
Theoretical pINot Available
GO Classification
Functions
  • nucleoside triphosphate adenylate kinase activity
  • ATP binding
  • GTP binding
Processes
  • GTP metabolic process
  • ADP biosynthetic process
  • ITP metabolic process
  • UTP metabolic process
  • blood coagulation
  • AMP metabolic process
Components
  • mitochondrion
  • mitochondrial matrix
General FunctionNucleoside triphosphate adenylate kinase activity
Specific FunctionInvolved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities.
Pfam Domain Function
Transmembrane RegionsNot Available
GenBank Protein IDNot Available
UniProtKB IDQ9UIJ7
UniProtKB Entry NameKAD3_HUMAN
Cellular LocationMitochondrion matrix
Gene sequence
>lcl|BSEQ0019579|GTP:AMP phosphotransferase AK3, mitochondrial (AK3)
ATGGGGGCGTCCGCGCGGCTGCTGCGAGCGGTGATCATGGGGGCCCCGGGCTCGGGCAAG
GGCACCGTGTCGTCGCGCATCACTACACACTTCGAGCTGAAGCACCTCTCCAGCGGGGAC
CTGCTCCGGGACAACATGCTGCGGGGCACAGGTTTTCCAAGGACACTTCCACAGGCAGAA
GCCCTAGATAGAGCTTATCAGATCGACACAGTGATTAACCTGAATGTGCCCTTTGAGGTC
ATTAAACAACGCCTTACTGCTCGCTGGATTCATCCCGCCAGTGGCCGAGTCTATAACATT
GAATTCAACCCTCCCAAAACTGTGGGCATTGATGACCTGACTGGGGAGCCTCTCATTCAG
CGTGAGGATGATAAACCAGAGACGGTTATCAAGAGACTAAAGGCTTATGAAGACCAAACA
AAGCCAGTCCTGGAATATTACCAGAAAAAAGGGGTGCTGGAAACATTCTCCGGAACAGAA
ACCAACAAGATTTGGCCCTATGTATATGCTTTCCTACAAACTAAAGTTCCACAAAGAAGC
CAGAAAGCTTCAGTTACTCCATGA
GenBank Gene IDNot Available
GeneCard IDNot Available
GenAtlas IDNot Available
HGNC IDHGNC:17376
Chromosome Location9
LocusNot Available
References
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