Voltage-dependent calcium channel gamma-5 subunit
Name | Voltage-dependent calcium channel gamma-5 subunit |
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Synonyms |
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Gene Name | CACNG5 |
Organism | Human |
Amino acid sequence | >lcl|BSEQ0020829|Voltage-dependent calcium channel gamma-5 subunit MSACGRKALTLLSSVFAVCGLGLLGIAVSTDYWLYLEEGVIVPQNQSTEIKMSLHSGLWR VCFLAGEERGRCFTIEYVMPMNTQLTSESTVNVLKMIRSATPFPLVSLFFMFIGFILNNI GHIRPHRTILAFVSGIFFILSGLSLVVGLVLYISSINDEMLNRTKDAETYFNYKYGWSFA FAAISFLLTESAGVMSVYLFMKRYTAEDMYRPHPGFYRPRLSNCSDYSGQFLHPDAWVRG RSPSDISSEASLQMNSNYPALLKCPDYDQMSSSPC |
Number of residues | 275 |
Molecular Weight | 30902.44 |
Theoretical pI | Not Available |
GO Classification | Functions
Processes
Components
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General Function | Voltage-gated calcium channel activity |
Specific Function | Regulates the gating properties of AMPA-selective glutamate receptors (AMPARs). Modulates their gating properties by accelerating their rates of activation, deactivation and desensitization. Displays subunit-specific AMPA receptor regulation. Shows specificity for GRIA1, GRIA4 and the long isoform of GRIA2. Thought to stabilize the calcium channel in an inactivated (closed) state (By similarity). |
Pfam Domain Function |
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Transmembrane Regions | 8-28 103-123 129-149 176-196 |
GenBank Protein ID | Not Available |
UniProtKB ID | Q9UF02 |
UniProtKB Entry Name | CCG5_HUMAN |
Cellular Location | Membrane |
Gene sequence | >lcl|BSEQ0020830|Voltage-dependent calcium channel gamma-5 subunit (CACNG5) ATGAGTGCCTGCGGGAGGAAGGCCCTGACCCTGCTGAGCAGTGTCTTTGCTGTCTGTGGC TTGGGCCTCCTGGGTATCGCGGTCAGCACCGACTACTGGCTGTACCTGGAGGAGGGTGTG ATTGTGCCCCAGAACCAGAGCACCGAGATCAAGATGTCCCTGCACTCAGGCCTCTGGCGG GTCTGCTTCCTTGCAGGTGAGGAGCGGGGGCGTTGCTTCACCATAGAATATGTGATGCCC ATGAACACCCAGCTGACATCCGAGTCCACGGTCAATGTTCTAAAGATGATCCGCTCAGCC ACACCATTCCCTCTGGTCAGCCTCTTCTTCATGTTCATTGGGTTTATCCTGAACAACATC GGACACATCCGTCCCCACCGGACGATACTGGCCTTTGTCTCTGGCATCTTCTTTATCCTC TCAGGCCTCTCTCTCGTGGTGGGCCTGGTGCTCTACATCTCCAGCATCAACGATGAGATG CTCAACAGGACCAAGGATGCAGAGACCTACTTCAACTACAAGTATGGGTGGTCGTTTGCC TTCGCCGCCATCTCCTTCCTTTTAACGGAGAGTGCCGGGGTGATGTCTGTGTACCTGTTT ATGAAGCGGTACACCGCGGAGGACATGTACAGGCCCCACCCTGGCTTCTACCGCCCTCGG CTGAGCAACTGCTCCGATTACTCAGGCCAGTTCCTACACCCAGACGCCTGGGTCAGGGGC CGCAGCCCCTCCGACATCTCCAGCGAGGCCTCCCTGCAGATGAACAGCAACTACCCCGCC TTGCTCAAGTGCCCCGACTATGATCAGATGTCCTCTTCACCCTGCTGA |
GenBank Gene ID | Not Available |
GeneCard ID | Not Available |
GenAtlas ID | Not Available |
HGNC ID | HGNC:1409 |
Chromosome Location | 17 |
Locus | Not Available |
References |
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