Voltage-dependent calcium channel gamma-4 subunit
Name | Voltage-dependent calcium channel gamma-4 subunit |
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Synonyms |
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Gene Name | CACNG4 |
Organism | Human |
Amino acid sequence | >lcl|BSEQ0017619|Voltage-dependent calcium channel gamma-4 subunit MVRCDRGLQMLLTTAGAFAAFSLMAIAIGTDYWLYSSAHICNGTNLTMDDGPPPRRARGD LTHSGLWRVCCIEGIYKGHCFRINHFPEDNDYDHDSSEYLLRIVRASSVFPILSTILLLL GGLCIGAGRIYSRKNNIVLSAGILFVAAGLSNIIGIIVYISSNTGDPSDKRDEDKKNHYN YGWSFYFGALSFIVAETVGVLAVNIYIEKNKELRFKTKREFLKASSSSPYARMPSYRYRR RRSRSSSRSTEASPSRDVSPMGLKITGAIPMGELSMYTLSREPLKVTTAASYSPDQEASF LQVHDFFQQDLKEGFHVSMLNRRTTPV |
Number of residues | 327 |
Molecular Weight | 36578.39 |
Theoretical pI | Not Available |
GO Classification | Functions
Processes
Components
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General Function | Voltage-gated calcium channel activity |
Specific Function | Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state. |
Pfam Domain Function |
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Transmembrane Regions | 10-30 108-128 137-157 187-207 |
GenBank Protein ID | Not Available |
UniProtKB ID | Q9UBN1 |
UniProtKB Entry Name | CCG4_HUMAN |
Cellular Location | Cell membrane |
Gene sequence | >lcl|BSEQ0017620|Voltage-dependent calcium channel gamma-4 subunit (CACNG4) ATGGTGCGATGCGACCGCGGGCTGCAGATGCTGCTGACCACGGCCGGAGCCTTCGCCGCC TTCTCGCTCATGGCCATCGCCATCGGCACCGACTACTGGCTGTACTCCAGCGCGCACATC TGCAACGGCACCAACCTGACCATGGACGACGGGCCCCCGCCCCGCCGCGCCCGCGGCGAC CTCACCCACTCTGGTCTGTGGCGGGTGTGCTGCATCGAAGGGATCTATAAAGGGCACTGC TTCCGGATCAATCACTTCCCAGAGGACAATGACTACGACCACGACAGCTCGGAGTACCTC CTCCGCATCGTGCGAGCCTCCAGCGTCTTCCCCATCCTCAGCACCATCCTGCTCCTGCTG GGTGGCCTGTGCATCGGTGCTGGCAGGATCTACAGCCGCAAGAACAACATCGTCCTCAGT GCCGGCATCCTCTTCGTGGCTGCAGGCCTCAGTAACATCATCGGTATCATCGTCTACATT TCCAGCAACACAGGTGACCCGAGTGACAAGCGGGACGAAGACAAAAAGAACCATTACAAC TACGGCTGGTCTTTTTACTTTGGAGCTCTGTCTTTCATTGTGGCTGAGACCGTGGGCGTC CTGGCTGTAAACATTTACATTGAGAAAAATAAAGAGTTGAGGTTTAAGACCAAACGGGAA TTCCTTAAGGCGTCTTCCTCTTCTCCTTATGCCAGGATGCCGAGCTACAGGTACCGGCGA CGGCGCTCGAGGTCCAGCTCAAGGTCCACCGAGGCCTCGCCCTCCAGGGACGTGTCGCCC ATGGGCCTGAAGATCACAGGGGCCATCCCCATGGGGGAGCTGTCCATGTACACGCTGTCC AGGGAGCCCCTCAAGGTGACCACCGCAGCCAGCTACAGCCCCGACCAGGAGGCCAGCTTC CTGCAGGTGCATGACTTTTTCCAGCAGGACCTGAAGGAAGGTTTCCACGTCAGCATGCTG AACCGACGGACGACCCCTGTGTGA |
GenBank Gene ID | Not Available |
GeneCard ID | Not Available |
GenAtlas ID | Not Available |
HGNC ID | HGNC:1408 |
Chromosome Location | 17 |
Locus | Not Available |
References |
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