NameAlpha-mannosidase 2C1
Synonyms
  • 3.2.1.24
  • Alpha mannosidase 6A8B
  • Alpha-D-mannoside mannohydrolase
  • MANA
  • MANA1
  • Mannosidase alpha class 2C member 1
Gene NameMAN2C1
OrganismHuman
Amino acid sequence
>lcl|BSEQ0009606|Alpha-mannosidase 2C1
MAAAPALKHWRTTLERVEKFVSPLYFTDCNLRGRLFGASCPVAVLSSFLTPERLPYQEAV
QRDFRPAQVGDSFGPTWWTCWFRVELTIPEAWVGQEVHLCWESDGEGLVWRDGEPVQGLT
KEGEKTSYVLTDRLGERDPRSLTLYVEVACNGLLGAGKGSMIAAPDPEKMFQLSRAELAV
FHRDVHMLLVDLELLLGIAKGLGKDNQRSFQALYTANQMVNVCDPAQPETFPVAQALASR
FFGQHGGESQHTIHATGHCHIDTAWLWPFKETVRKCARSWVTALQLMERNPEFIFACSQA
QQLEWVKSRYPGLYSRIQEFACRGQFVPVGGTWVEMDGNLPSGEAMVRQFLQGQNFFLQE
FGKMCSEFWLPDTFGYSAQLPQIMHGCGIRRFLTQKLSWNLVNSFPHHTFFWEGLDGSRV
LVHFPPGDSYGMQGSVEEVLKTVANNRDKGRANHSAFLFGFGDGGGGPTQTMLDRLKRLS
NTDGLPRVQLSSPRQLFSALESDSEQLCTWVGELFLELHNGTYTTHAQIKKGNRECERIL
HDVELLSSLALARSAQFLYPAAQLQHLWRLLLLNQFHDVVTGSCIQMVAEEAMCHYEDIR
SHGNTLLSAAAAALCAGEPGPEGLLIVNTLPWKRIEVMALPKPGGAHSLALVTVPSMGYA
PVPPPTSLQPLLPQQPVFVVQETDGSVTLDNGIIRVKLDPTGRLTSLVLVASGREAIAEG
AVGNQFVLFDDVPLYWDAWDVMDYHLETRKPVLGQAGTLAVGTEGGLRGSAWFLLQISPN
SRLSQEVVLDVGCPYVRFHTEVHWHEAHKFLKVEFPARVRSSQATYEIQFGHLQRPTHYN
TSWDWARFEVWAHRWMDLSEHGFGLALLNDCKYGASVRGSILSLSLLRAPKAPDATADTG
RHEFTYALMPHKGSFQDAGVIQAAYSLNFPLLALPAPSPAPATSWSAFSVSSPAVVLETV
KQAESSPQRRSLVLRLYEAHGSHVDCWLHLSLPVQEAILCDLLERPDPAGHLTLRDNRLK
LTFSPFQVLSLLLVLQPPPH
Number of residues1040
Molecular Weight115834.355
Theoretical pINot Available
GO Classification
Functions
  • alpha-mannosidase activity
  • zinc ion binding
  • carbohydrate binding
Processes
  • protein deglycosylation
  • mannose metabolic process
Components
  • vacuole
General FunctionZinc ion binding
Specific FunctionNot Available
Pfam Domain Function
Transmembrane RegionsNot Available
GenBank Protein IDNot Available
UniProtKB IDQ9NTJ4
UniProtKB Entry NameMA2C1_HUMAN
Cellular LocationNot Available
Gene sequence
>lcl|BSEQ0020854|Alpha-mannosidase 2C1 (MAN2C1)
ATGGCGGCTGCGCCGGCCTTGAAGCACTGGCGCACCACGCTGGAGCGGGTGGAGAAGTTC
GTGTCGCCGCTCTACTTTACCGACTGTAACCTCCGCGGCAGGCTTTTTGGGGCCAGCTGC
CCTGTGGCTGTGCTCTCCAGCTTCCTGACGCCGGAGAGACTTCCCTACCAGGAGGCAGTC
CAGCGGGACTTCCGCCCCGCGCAGGTCGGCGACAGCTTCGGACCCACATGGTGGACCTGC
TGGTTCCGGGTGGAGCTGACCATCCCAGAGGCATGGGTGGGCCAGGAAGTTCACCTTTGC
TGGGAAAGTGATGGAGAAGGTCTGGTGTGGCGTGATGGAGAACCTGTCCAGGGTTTAACC
AAAGAGGGTGAGAAGACCAGCTATGTCCTGACTGACAGGCTGGGGGAAAGAGACCCCCGA
AGCCTCACTCTCTATGTGGAAGTAGCCTGCAATGGGCTCCTGGGGGCCGGGAAGGGAAGC
ATGATTGCAGCCCCTGACCCTGAGAAGATGTTCCAGCTGAGCCGGGCTGAGCTAGCTGTG
TTCCACCGGGATGTCCACATGCTCCTGGTGGATCTGGAGCTGCTGCTGGGCATAGCCAAG
GGCCTCGGGAAGGACAACCAGCGCAGCTTCCAGGCCCTGTACACAGCCAATCAGATGGTG
AACGTGTGTGACCCTGCCCAGCCCGAGACCTTCCCAGTGGCCCAGGCCCTGGCCTCCAGG
TTCTTTGGCCAACATGGGGGTGAAAGCCAACACACCATTCATGCCACAGGGCACTGCCAC
ATTGATACAGCCTGGCTTTGGCCCTTCAAAGAGACTGTGAGGAAATGTGCCCGGAGCTGG
GTGACCGCCCTGCAGCTCATGGAGCGGAACCCTGAGTTCATCTTTGCCTGCTCCCAGGCG
CAGCAGCTGGAATGGGTGAAGAGCCGCTACCCTGGCCTGTACTCCCGCATCCAGGAGTTT
GCGTGCCGTGGGCAGTTTGTGCCTGTGGGGGGCACCTGGGTGGAGATGGATGGGAACCTG
CCCAGTGGAGAGGCCATGGTGAGGCAGTTTTTGCAGGGCCAGAACTTCTTTCTGCAGGAG
TTTGGGAAGATGTGCTCTGAGTTCTGGCTGCCGGACACCTTTGGCTACTCAGCACAGCTC
CCCCAGATCATGCACGGCTGTGGCATCAGGCGCTTTCTCACCCAGAAATTGAGCTGGAAT
TTGGTGAACTCCTTCCCACACCATACATTTTTCTGGGAGGGCCTGGATGGCTCCCGTGTA
CTGGTCCACTTCCCACCTGGCGACTCCTATGGGATGCAGGGCAGCGTGGAGGAGGTGCTG
AAGACCGTGGCCAACAACCGGGACAAGGGGCGGGCCAACCACAGTGCCTTCCTCTTTGGC
TTTGGGGATGGGGGTGGTGGCCCCACCCAGACCATGCTGGACCGCCTGAAGCGCCTGAGC
AATACGGATGGGCTGCCCAGGGTGCAGCTATCTTCTCCAAGACAGCTCTTCTCAGCACTG
GAGAGTGACTCAGAGCAGCTGTGCACGTGGGTTGGGGAGCTCTTCTTGGAGCTGCACAAT
GGCACATACACCACCCATGCCCAGATCAAGAAGGGGAACCGGGAATGTGAGCGGATCCTG
CACGACGTGGAGCTGCTCAGTAGCCTGGCCCTGGCCCGCAGTGCCCAGTTCCTATACCCA
GCAGCCCAGCTGCAGCACCTCTGGAGGCTCCTTCTTCTGAACCAGTTCCATGATGTGGTG
ACTGGAAGCTGCATCCAGATGGTGGCAGAGGAAGCCATGTGCCATTATGAAGACATCCGT
TCCCATGGCAATACACTGCTCAGCGCTGCAGCCGCAGCCCTGTGTGCTGGGGAGCCAGGT
CCTGAGGGCCTCCTCATCGTCAACACACTGCCCTGGAAGCGGATCGAAGTGATGGCCCTG
CCCAAACCGGGCGGGGCCCACAGCCTAGGCCTCACCCCCAGCCCTGGTGACAGTGCCCAG
CATGGGCTATGCTCCTGTTCCTCCCCCCACCTCACTGCAGCCCCTGCTGCCCCAGCAGCC
TGTGTTCGTAGTGCAAGAGCCCCTACAGACTCAGCCTCAAGGCCTCCTCCCACAAAGACT
GATGGCTCCGTGACTCTGGACAATGGCATCATCCGAGTGAAGCTGGACCCAACTGGTCGC
CTGACGTCCTTGGTCCTGGTGGCCTCTGGCAGGGAGGCCATTGCTGAGGGCGCCGTGGGG
AACCAGTTTGTGCTATTTGATGATGTCCCCTTGTACTGGGATGCATGGGACGTCATGGAC
TACCACCTGGAGACACGGAAGCCTGTGCTGGGCCAGGCAGGGACCCTGGCAGTGGGCACC
GAGGGCGGCCTGCGGGGCAGCGCCTGGTTCTTGCTACAGATCAGCCCCAACAGTCGGCTT
AGCCAGGAGGTTGTGCTGGACGTTGGCTGCCCCTATGTCCGCTTCCACACCGAGGTACAC
TGGCATGAGGCCCACAAGTTCCTGAAGGTGGAGTTCCCTGCTCGCGTGCGGAGTTCCCAG
GCCACCTATGAGATCCAGTTTGGGCACCTGCAGCGACCTACCCACTACAATACCTCTTGG
GACTGGGCTCGATTTGAGGTGTGGGCCCATCGCTGGATGGATCTGTCAGAACACGGCTTT
GGGCTGGCCCTGCTCAACGACTGCAAGTATGGCGCGTCAGTGCGAGGCAGCATCCTCAGC
CTCTCGCTCTTGCGGGCGCCTAAAGCCCCGGACGCTACTGCTGACACGGGGCGCCACGAG
TTCACCTATGCACTGATGCCGCACAAGGGCTCTTTCCAGGATGCTGGCGTTATCCAAGCT
GCCTACAGCCTAAACTTCCCCCTGTTGGCTCTGCCAGCCCCCAGCCCAGCGCCCGCCACC
TCCTGGAGTGCGTTTTCCGTGTCTTCACCCGCGGTCGTATTGGAGACCGTCAAGCAGGCG
GAGAGCAGCCCCCAGCGCCGCTCGCTGGTCCTGAGGCTGTATGAGGCCCACGGCAGCCAC
GTGGACTGCTGGCTGCACTTGTCGCTGCCGGTTCAGGAGGCCATCCTCTGCGATCTCTTG
GAGCGACCAGACCCTGCTGGCCACTTGACCCTTCGGGACAACCGCCTGAAGCTCACCTTT
TCTCCCTTCCAAGTGCTGTCCCTGTTGCTCGTGCTTCAGCCTCCGCCACACTGA
GenBank Gene IDNot Available
GeneCard IDNot Available
GenAtlas IDNot Available
HGNC IDHGNC:6827
Chromosome Location15
LocusNot Available
References
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