Kinesin light chain 2

NameKinesin light chain 2
Synonyms
  • KLC 2
Gene NameKLC2
OrganismHuman
Amino acid sequence
>lcl|BSEQ0009172|Kinesin light chain 2
MAMMVFPREEKLSQDEIVLGTKAVIQGLETLRGEHRALLAPLVAPEAGEAEPGSQERCIL
LRRSLEAIELGLGEAQVILALSSHLGAVESEKQKLRAQVRRLVQENQWLREELAGTQQKL
QRSEQAVAQLEEEKQHLLFMSQIRKLDEDASPNEEKGDVPKDTLDDLFPNEDEQSPAPSP
GGGDVSGQHGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVA
TMLNILALVYRDQNKYKEAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKE
AEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYATRLGP
DDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRAHEKEFGSVNGDNKPIWMHAEEREE
SKDKRRDSAPYGEYGSWYKACKVDSPTVNTTLRSLGALYRRQGKLEAAHTLEDCASRNRK
QGLDPASQTKVVELLKDGSGRRGDRRSSRDMAGGAGPRSESDLEDVGPTAEWNGDGSGSL
RRSGSFGKLRDALRRSSEMLVKKLQGGTPQEPPNPRMKRASSLNFLNKSVEEPTQPGGTG
LSDSRTLSSSSMDLSRRSSLVG
Number of residues622
Molecular Weight68933.985
Theoretical pINot Available
GO Classification
Functions
  • microtubule motor activity
  • kinesin binding
Processes
  • small GTPase mediated signal transduction
  • antigen processing and presentation of exogenous peptide antigen via MHC class II
  • axon cargo transport
  • microtubule-based movement
  • blood coagulation
Components
  • cytosol
  • neuron projection
  • ciliary rootlet
  • kinesin complex
  • kinesin I complex
  • membrane
  • protein complex
  • microtubule
General FunctionMicrotubule motor activity
Specific FunctionKinesin is a microtubule-associated force-producing protein that may play a role in organelle transport. The light chain may function in coupling of cargo to the heavy chain or in the modulation of its ATPase activity (By similarity).
Pfam Domain Function
Transmembrane RegionsNot Available
GenBank Protein IDNot Available
UniProtKB IDQ9H0B6
UniProtKB Entry NameKLC2_HUMAN
Cellular LocationCytoplasm
Gene sequence
>lcl|BSEQ0017708|Kinesin light chain 2 (KLC2)
ATGGCCATGATGGTGTTTCCGCGGGAGGAGAAGCTGAGCCAGGATGAGATCGTGCTGGGC
ACCAAGGCTGTCATCCAGGGACTGGAGACTCTGCGTGGGGAGCATCGTGCCCTGCTGGCT
CCTCTGGTTGCACCTGAGGCCGGCGAAGCCGAGCCTGGCTCGCAGGAGCGCTGCATCCTC
CTGCGTCGCTCCCTGGAAGCCATTGAGCTTGGGCTGGGGGAGGCCCAGGAGGAGAAGGGG
GACGTCCCCAAAGACACACTGGATGACCTGTTCCCCAATGAGGATGAGCAGAGCCCAGCC
CCTAGCCCAGGAGGAGGGGATGTGTCTGGTCAGCATGGGGGCTACGAGATCCCGGCCCGG
CTCCGCACCCTGCACAACCTGGTGATCCAATACGCCTCACAGGGCCGCTACGAGGTAGCT
GTGCCACTCTGCAAGCAGGCACTCGAAGACCTGGAGAAGACGTCAGGCCACGACCACCCT
GACGTTGCCACCATGCTGAACATCCTGGCACTGGTCTATCGGGATCAGAACAAGTACAAG
GAGGCTGCCCACCTGCTCAATGATGCTCTGGCCATCCGGGAGAAAACACTGGGCAAGGAC
CACCCAGCCGTGGCTGCGACACTAAACAACCTGGCAGTCCTGTATGGCAAGAGGGGCAAG
TACAAGGAGGCTGAGCCATTGTGCAAGCGGGCACTGGAGATCCGGGAGAAGGTCCTGGGC
AAGTTTCACCCAGATGTGGCCAAGCAGCTCAGCAACCTGGCCCTGCTGTGCCAGAACCAG
GGCAAAGCTGAGGAGGTGGAATATTACTATCGGCGGGCACTGGAGATCTATGCTACACGC
CTCGGGCCCGATGACCCCAATGTGGCCAAGACCAAGAACAACCTGGCTTCCTGCTACCTG
AAGCAGGGCAAGTACCAGGATGCGGAGACCTTGTACAAGGAGATCCTCACCCGCGCTCAT
GAGAAAGAGTTTGGCTCTGTCAATGGGGACAACAAGCCCATCTGGATGCACGCAGAGGAG
CGGGAGGAAAGCAAGGATAAGCGCCGGGACAGCGCCCCCTATGGGGAATACGGCAGCTGG
TACAAGGCCTGTAAAGTAGACAGCCCCACAGTCAACACCACCCTGCGCAGCTTGGGGGCC
CTATACCGGCGCCAGGGCAAGCTGGAAGCCGCGCACACACTAGAGGACTGTGCCAGCCGT
AACCGCAAGCAGGGTTTGGACCCCGCAAGCCAGACCAAGGTGGTAGAACTGCTGAAAGAT
GGCAGTGGCAGGCGGGGAGACCGCCGCAGCAGCCGAGACATGGCTGGGGGTGCCGGGCCT
CGGTCTGAGTCTGACCTCGAGGACGTGGGACCTACAGCTGAGTGGAATGGGGATGGCAGT
GGCTCCTTGAGGCGCAGCGGTTCCTTTGGGAAACTCCGGGATGCCCTGAGGCGCAGCAGT
GAGATGCTGGTAAAGAAGCTGCAGGGGGGCACCCCCCAGGAGCCCCCTAACCCCAGGATG
AAGCGGGCCAGTTCCCTCAACTTCCTCAACAAGAGCGTGGAAGAGCCGACCCAGCCTGGA
GGCACAGGTCTCTCTGACAGCCGCACTCTCAGCTCCAGCTCCATGGACCTCTCCCGACGA
AGCTCCCTGGTGGGCTAA
GenBank Gene IDNot Available
GeneCard IDNot Available
GenAtlas IDNot Available
HGNC IDHGNC:20716
Chromosome Location11
LocusNot Available
References
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