NameEmopamil-binding protein-like
Synonyms
  • EBRP
  • Emopamil-binding-related protein
  • ERP
Gene NameEBPL
OrganismHuman
Amino acid sequence
>lcl|BSEQ0009307|Emopamil-binding protein-like
MGAEWELGAEAGGSLLLCAALLAAGCALGLRLGRGQGAADRGALIWLCYDALVHFALEGP
FVYLSLVGNVANSDGLIASLWKEYGKADARWVYFDPTIVSVEILTVALDGSLALFLIYAI
VKEKYYRHFLQITLCVCELYGCWMTFLPEWLTRSPNLNTSNWLYCWLYLFFFNGVWVLIP
GLLLWQSWLELKKMHQKETSSVKKFQ
Number of residues206
Molecular Weight23203.965
Theoretical pINot Available
GO Classification
Functions
  • cholestenol delta-isomerase activity
Processes
  • sterol metabolic process
Components
  • endoplasmic reticulum
  • endoplasmic reticulum membrane
  • integral component of membrane
General FunctionCholestenol delta-isomerase activity
Specific FunctionDoes not possess sterol isomerase activity and does not bind sigma ligands.
Pfam Domain Function
Transmembrane Regions10-30 42-62 101-121 165-185
GenBank Protein IDNot Available
UniProtKB IDQ9BY08
UniProtKB Entry NameEBPL_HUMAN
Cellular LocationEndoplasmic reticulum membrane
Gene sequenceNot Available
GenBank Gene IDNot Available
GeneCard IDNot Available
GenAtlas IDNot Available
HGNC IDHGNC:18061
Chromosome LocationNot Available
LocusNot Available
References
  1. Moebius FF, Fitzky BU, Wietzorrek G, Haidekker A, Eder A, Glossmann H: Cloning of an emopamil-binding protein (EBP)-like protein that lacks sterol delta8-delta7 isomerase activity. Biochem J. 2003 Aug 15;374(Pt 1):229-37. 12760743
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