NameProtein phosphatase 1 regulatory subunit 16A
Synonyms
  • Myosin phosphatase-targeting subunit 3
  • MYPT3
Gene NamePPP1R16A
OrganismHuman
Amino acid sequence
>lcl|BSEQ0009124|Protein phosphatase 1 regulatory subunit 16A
MAEHLELLAEMPMVGRMSTQERLKHAQKRRAQQVKMWAQAEKEAQGKKGPGERPRKEAAS
QGLLKQVLFPPSVVLLEAAARNDLEEVRQFLGSGVSPDLANEDGLTALHQCCIDDFREMV
QQLLEAGANINACDSECWTPLHAAATCGHLHLVELLIASGANLLAVNTDGNMPYDLCDDE
QTLDCLETAMADRGITQDSIEAARAVPELRMLDDIRSRLQAGADLHAPLDHGATLLHVAA
ANGFSEAAALLLEHRASLSAKDQDGWEPLHAAAYWGQVPLVELLVAHGADLNAKSLMDET
PLDVCGDEEVRAKLLELKHKHDALLRAQSRQRSLLRRRTSSAGSRGKVVRRVSLTQRTDL
YRKQHAQEAIVWQQPPPTSPEPPEDNDDRQTGAELRPPPPEEDNPEVVRPHNGRVGGSPV
RHLYSKRLDRSVSYQLSPLDSTTPHTLVHDKAHHTLADLKRQRAAAKLQRPPPEGPESPE
TAEPGLPGDTVTPQPDCGFRAGGDPPLLKLTAPAVEAPVERRPCCLLM
Number of residues528
Molecular Weight57810.795
Theoretical pINot Available
GO Classification
Functions
  • protein phosphatase type 1 regulator activity
Components
  • plasma membrane
General FunctionProtein phosphatase type 1 regulator activity
Specific FunctionInhibits protein phosphatase 1 activity toward phosphorylase, myosin light chain and myosin substrates.
Pfam Domain Function
Transmembrane RegionsNot Available
GenBank Protein IDNot Available
UniProtKB IDQ96I34
UniProtKB Entry NamePP16A_HUMAN
Cellular LocationCell membrane
Gene sequence
>lcl|BSEQ0013627|Protein phosphatase 1 regulatory subunit 16A (PPP1R16A)
ATGGCCGAGCACCTGGAGCTGCTGGCAGAGATGCCCATGGTGGGCAGGATGAGCACACAG
GAGCGGCTGAAGCATGCCCAGAAGCGGCGCGCCCAGCAGGTGAAGATGTGGGCCCAGGCT
GAGAAGGAGGCCCAGGGCAAGAAGGGTCCTGGGGAGCGTCCCCGGAAGGAGGCAGCCAGC
CAAGGGCTCCTGAAGCAGGTCCTCTTCCCTCCCAGTGTTGTCCTTCTGGAGGCCGCTGCC
CGAAATGACCTGGAAGAAGTCCGCCAGTTCCTTGGGAGTGGGGTCAGCCCTGACTTGGCC
AACGAGGACGGCCTGACGGCCCTGCACCAGTGCTGCATTGATGATTTCCGAGAGATGGTG
CAGCAGCTCCTGGAGGCTGGGGCCAACATCAATGCCTGTGACAGTGAGTGCTGGACGCCT
CTGCATGCTGCGGCCACCTGCGGCCACCTGCACCTGGTGGAGCTGCTCATCGCCAGTGGC
GCCAATCTCCTGGCGGTCAACACCGACGGGAACATGCCCTATGACCTGTGTGATGATGAG
CAGACGCTGGACTGCCTGGAGACTGCCATGGCCGACCGTGGCATCACCCAGGACAGCATC
GAGGCCGCCCGGGCCGTGCCAGAACTGCGCATGCTGGACGACATCCGGAGCCGGCTGCAG
GCCGGGGCAGACCTCCATGCCCCCCTGGACCACGGGGCCACGCTGCTGCACGTCGCAGCC
GCCAACGGGTTCAGCGAGGCGGCTGCCCTGCTGCTGGAACACCGAGCCAGCCTGAGCGCT
AAGGACCAAGACGGCTGGGAGCCGCTGCACGCCGCGGCCTACTGGGGCCAGGTGCCCCTG
GTGGAGCTGCTCGTGGCGCACGGGGCCGACCTGAACGCAAAGTCCCTGATGGACGAGACG
CCCCTTGATGTGTGCGGGGACGAGGAGGTGCGGGCCAAGCTGCTGGAGCTGAAGCACAAG
CACGACGCCCTCCTGCGCGCCCAGAGCCGCCAGCGCTCCTTGCTGCGCCGCCGCACCTCC
AGCGCCGGCAGCCGCGGGAAGGTGGTGAGGCGGGTGAGCCTAACCCAGCGCACCGACCTG
TACCGCAAGCAGCACGCCCAGGAGGCCATCGTGTGGCAACAGCCGCCGCCCACCAGCCCG
GAGCCGCCCGAGGACAACGATGACCGCCAGACAGGCGCAGAGCTCAGGCCGCCGCCCCCG
GAGGAGGACAACCCCGAAGTGGTCAGGCCGCACAATGGCCGAGTAGGGGGCTCCCCAGTG
CGGCATCTATACTCCAAGCGACTAGACCGGAGTGTCTCCTACCAGCTGAGCCCCCTGGAC
AGCACCACCCCCCACACCCTGGTCCACGACAAGGCCCACCACACCCTGGCTGACCTGAAG
CGCCAGCGAGCTGCTGCCAAGCTGCAGCGACCCCCACCTGAGGGGCCCGAGAGCCCTGAG
ACAGCTGAGCCTGGCCTGCCTGGTGACACGGTGACCCCCCAGCCTGACTGTGGCTTCAGG
GCAGGCGGGGACCCACCCCTGCTCAAGCTCACAGCCCCGGCGGTGGAGGCTCCCGTGGAG
AGGAGGCCGTGCTGCCTGCTCATGTGA
GenBank Gene IDNot Available
GeneCard IDNot Available
GenAtlas IDNot Available
HGNC IDHGNC:14941
Chromosome Location8
LocusNot Available
References
  1. Gerhard DS, Wagner L, Feingold EA, Shenmen CM, Grouse LH, Schuler G, Klein SL, Old S, Rasooly R, Good P, Guyer M, Peck AM, Derge JG, Lipman D, Collins FS, Jang W, Sherry S, Feolo M, Misquitta L, Lee E, Rotmistrovsky K, Greenhut SF, Schaefer CF, Buetow K, Bonner TI, Haussler D, Kent J, Kiekhaus M, Furey T, Brent M, Prange C, Schreiber K, Shapiro N, Bhat NK, Hopkins RF, Hsie F, Driscoll T, Soares MB, Casavant TL, Scheetz TE, Brown-stein MJ, Usdin TB, Toshiyuki S, Carninci P, Piao Y, Dudekula DB, Ko MS, Kawakami K, Suzuki Y, Sugano S, Gruber CE, Smith MR, Simmons B, Moore T, Waterman R, Johnson SL, Ruan Y, Wei CL, Mathavan S, Gunaratne PH, Wu J, Garcia AM, Hulyk SW, Fuh E, Yuan Y, Sneed A, Kowis C, Hodgson A, Muzny DM, McPherson J, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madari A, Young AC, Wetherby KD, Granite SJ, Kwong PN, Brinkley CP, Pearson RL, Bouffard GG, Blakesly RW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Griffith M, Griffith OL, Krzywinski MI, Liao N, Morin R, Palmquist D, Petrescu AS, Skalska U, Smailus DE, Stott JM, Schnerch A, Schein JE, Jones SJ, Holt RA, Baross A, Marra MA, Clifton S, Makowski KA, Bosak S, Malek J: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Genome Res. 2004 Oct;14(10B):2121-7. 15489334