NameTranslational activator GCN1
Synonyms
  • GCN1-like protein 1
  • HsGCN1
  • KIAA0219
Gene NameGCN1L1
OrganismHuman
Amino acid sequence
>lcl|BSEQ0009838|Translational activator GCN1
MAADTQVSETLKRFAGKVTTASVKERREILSELGKCVAGKDLPEGAVKGLCKLFCLTLHR
YRDAASRRALQAAIQQLAEAQPEATAKNLLHSLQSSGIGSKAGVPSKSSGSAALLALTWT
CLLVRIVFPSRAKRQGDIWNKLVEVQCLLLLEVLGGSHKHAVDGAVKKLTKLWKENPGLV
EQYLSAILSLEPNQNYAGMLGLLVQFCTSHKEMDVVSQHKSALLDFYMKNILMSKVKPPK
YLLDSCAPLLRYLSHSEFKDLILPTIQKSLLRSPENVIETISSLLASVTLDLSQYAMDIV
KGLAGHLKSNSPRLMDEAVLALRNLARQCSDSSAMESLTKHLFAILGGSEGKLTVVAQKM
SVLSGIGSVSHHVVSGPSSQVLNGIVAELFIPFLQQEVHEGTLVHAVSVLALWCNRFTME
VPKKLTEWFKKAFSLKTSTSAVRHAYLQCMLASYRGDTLLQALDLLPLLIQTVEKAASQS
TQVPTITEGVAAALLLLKLSVADSQAEAKLSSFWQLIVDEKKQVFTSEKFLVMASEDALC
TVLHLTERLFLDHPHRLTGNKVQQYHRALVAVLLSRTWHVRRQAQQTVRKLLSSLGGFKL
AHGLLEELKTVLSSHKVLPLEALVTDAGEVTEAGKAYVPPRVLQEALCVISGVPGLKGDV
TDTEQLAQEMLIISHHPSLVAVQSGLWPALLARMKIDPEAFITRHLDQIIPRMTTQSPLN
QSSMNAMGSLSVLSPDRVLPQLISTITASVQNPALRLVTREEFAIMQTPAGELYDKSIIQ
SAQQDSIKKANMKRENKAYSFKEQIIELELKEEIKKKKGIKEEVQLTSKQKEMLQAQLDR
EAQVRRRLQELDGELEAALGLLDIILAKNPSGLTQYIPVLVDSFLPLLKSPLAAPRIKNP
FLSLAACVMPSRLKALGTLVSHVTLRLLKPECVLDKSWCQEELSVAVKRAVMLLHTHTIT
SRVGKGEPGAAPLSAPAFSLVFPFLKMVLTEMPHHSEEEEEWMAQILQILTVQAQLRASP
NTPPGRVDENGPELLPRVAMLRLLTWVIGTGSPRLQVLASDTLTTLCASSSGDDGCAFAE
QEEVDVLLCALQSPCASVRETVLRGLMELHMVLPAPDTDEKNGLNLLRRLWVVKFDKEEE
IRKLAERLWSMMGLDLQPDLCSLLIDDVIYHEAAVRQAGAEALSQAVARYQRQAAEVMGR
LMEIYQEKLYRPPPVLDALGRVISESPPDQWEARCGLALALNKLSQYLDSSQVKPLFQFF
VPDALNDRHPDVRKCMLDAALATLNTHGKENVNSLLPVFEEFLKNAPNDASYDAVRQSVV
VLMGSLAKHLDKSDPKVKPIVAKLIAALSTPSQQVQESVASCLPPLVPAIKEDAGGMIQR
LMQQLLESDKYAERKGAAYGLAGLVKGLGILSLKQQEMMAALTDAIQDKKNFRRREGALF
AFEMLCTMLGKLFEPYVVHVLPHLLLCFGDGNQYVREAADDCAKAVMSNLSAHGVKLVLP
SLLAALEEESWRTKAGSVELLGAMAYCAPKQLSSCLPNIVPKLTEVLTDSHVKVQKAGQQ
ALRQIGSVIRNPEILAIAPVLLDALTDPSRKTQKCLQTLLDTKFVHFIDAPSLALIMPIV
QRAFQDRSTDTRKMAAQIIGNMYSLTDQKDLAPYLPSVTPGLKASLLDPVPEVRTVSAKA
LGAMVKGMGESCFEDLLPWLMETLTYEQSSVDRSGAAQGLAEVMAGLGVEKLEKLMPEIV
ATASKVDIAPHVRDGYIMMFNYLPITFGDKFTPYVGPIIPCILKALADENEFVRDTALRA
GQRVISMYAETAIALLLPQLEQGLFDDLWRIRFSSVQLLGDLLFHISGVTGKMTTETASE
DDNFGTAQSNKAIITALGVERRNRVLAGLYMGRSDTQLVVRQASLHVWKIVVSNTPRTLR
EILPTLFGLLLGFLASTCADKRTIAARTLGDLVRKLGEKILPEIIPILEEGLRSQKSDER
QGVCIGLSEIMKSTSRDAVLYFSESLVPTARKALCDPLEEVREAAAKTFEQLHSTIGHQA
LEDILPFLLKQLDDEEVSEFALDGLKQVMAIKSRVVLPYLVPKLTTPPVNTRVLAFLSSV
AGDALTRHLGVILPAVMLALKEKLGTPDEQLEMANCQAVILSVEDDTGHRIIIEYLLEAT
RSPEVGMRQAAAIILNIYCSRSKADYTSHLRSLVSGLIRLFNDSSPVVLEESWDALNAIT
KKLDAGNQLALIEELHKEIRLIGNESKGEHVPGFCLPKKGVTSILPVLREGVLTGSPEQK
EEAAKALGLVIRLTSADALRPSVVSITGPLIRILGDRFSWNVKAALLETLSLLLAKVGIA
LKPFLPQLQTTFTKALQDSNRGVRLKAADALGKLISIHIKVDPLFTELLNGIRAMEDPGV
RDTMLQALRFVIQGAGAKVDAVIRKNIVSLLLSMLGHDEDNTRISSAGCLGELCAFLTEE
ELSAVLQQCLLADVSGIDWMVRHGRSLALSVAVNVAPGRLCAGRYSSDVQEMILSSATAD
RIPIAVSGVRGMGFLMRHHIETGGGQLPAKLSSLFVKCLQNPSSDIRLVAEKMIWWANKD
PLPPLDPQAIKPILKALLDNTKDKNTVVRAYSDQAIVNLLKMRQGEEVFQSLSKILDVAS
LEVLNEVNRRSLKKLASQADSTEQVDDTILT
Number of residues2671
Molecular Weight292755.02
Theoretical pINot Available
GO Classification
Functions
  • poly(A) RNA binding
  • translation factor activity, RNA binding
Processes
  • translation
  • regulation of translation
  • cellular response to amino acid starvation
  • cellular response to leucine starvation
  • positive regulation of transcription from RNA polymerase II promoter in response to stress
Components
  • ribosome
  • polysome
  • cytoplasm
  • membrane
General FunctionTranslation factor activity, rna binding
Specific FunctionActs as a translation activator that mediates translational control and perform an EF3-related function on the ribosome by regulating GCN2 protein kinase (EIF2AK1-4) activity.
Pfam Domain Function
Transmembrane RegionsNot Available
GenBank Protein IDNot Available
UniProtKB IDQ92616
UniProtKB Entry NameGCN1L_HUMAN
Cellular LocationNot Available
Gene sequence
>lcl|BSEQ0013941|Translational activator GCN1 (GCN1L1)
ATGGCGGCGGACACGCAGGTTTCCGAGACACTAAAGCGTTTTGCAGGGAAGGTGACAACA
GCCAGTGTAAAGGAACGGAGAGAAATCCTCAGTGAACTTGGGAAGTGTGTTGCTGGAAAA
GATCTTCCAGAGGGAGCAGTGAAGGGGCTCTGCAAATTGTTCTGCTTGACTCTGCATCGA
TATAGAGATGCAGCCTCCCGCAGGGCCTTGCAGGCAGCCATCCAGCAGTTGGCTGAGGCC
CAGCCAGAAGCCACTGCTAAGAACCTTCTACACTCTCTGCAGTCTTCTGGTATAGGCTCC
AAAGCAGGTGTTCCCAGTAAGAGCAGTGGCTCTGCCGCCTTGCTGGCCTTGACCTGGACC
TGCCTCCTGGTGCGCATTGTCTTTCCATCGAGAGCCAAGCGACAAGGAGACATCTGGAAC
AAACTGGTGGAAGTGCAGTGCCTGCTCTTGCTGGAGGTGCTGGGTGGCTCCCACAAGCAC
GCCGTGGATGGTGCTGTGAAGAAACTCACGAAGCTGTGGAAAGAGAACCCCGGGCTGGTG
GAACAGTACTTGTCAGCCATTCTCAGCCTAGAGCCCAACCAGAACTATGCTGGCATGCTG
GGGCTGCTGGTGCAGTTCTGCACGAGTCACAAGGAGATGGACGTGGTCAGTCAGCACAAG
AGCGCCCTACTGGACTTTTACATGAAGAACATCCTGATGAGCAAAGTCAAGCCTCCGAAG
TACCTGTTGGATAGCTGTGCCCCTCTGCTCCGATACCTGTCCCACTCAGAATTTAAGGAT
CTGATACTGCCCACCATACAGAAGTCCTTACTGAGGAGTCCAGAGAATGTTATTGAAACT
ATTTCTAGTCTGCTGGCATCAGTGACGCTTGACCTCAGCCAGTATGCCATGGACATCGTG
AAAGGACTGGCTGGTCACCTGAAATCCAACAGTCCCCGCCTGATGGATGAAGCTGTGCTG
GCACTGCGGAACCTGGCACGCCAGTGCAGTGACTCTTCGGCCATGGAATCCCTGACCAAG
CACCTATTTGCTATCCTCGGAGGCTCGGAAGGAAAACTAACTGTTGTAGCCCAGAAGATG
AGCGTCCTCTCAGGGATTGGGAGCGTCAGTCATCACGTGGTGTCTGGACCTTCCAGTCAG
GTCCTGAATGGGATCGTGGCTGAGCTGTTCATCCCGTTCCTTCAGCAGGAAGTTCATGAA
GGGACCTTGGTACACGCTGTCTCAGTCCTGGCTCTCTGGTGTAACCGATTCACTATGGAA
GTGCCCAAGAAGCTCACTGAATGGTTCAAAAAAGCTTTCAGCCTTAAAACCTCCACATCT
GCGGTGAGGCATGCCTACCTGCAGTGCATGTTGGCCTCTTACCGGGGTGACACGCTGTTG
CAGGCCCTGGACTTACTGCCCTTGCTCATCCAGACAGTGGAGAAGGCAGCCTCCCAAAGC
ACTCAGGTTCCCACCATCACTGAAGGGGTTGCCGCAGCCTTGTTGCTCTTAAAGTTGTCA
GTGGCTGACTCACAGGCTGAGGCCAAACTGAGCAGTTTCTGGCAGTTGATTGTGGATGAG
AAAAAGCAGGTTTTCACTTCTGAGAAATTCCTGGTCATGGCTTCAGAGGATGCCCTGTGT
ACTGTGTTGCATCTGACAGAGAGACTTTTCCTTGACCACCCGCATAGACTCACTGGCAAC
AAAGTTCAGCAGTACCACCGGGCTCTGGTGGCGGTGCTCCTGAGCCGCACCTGGCACGTC
CGCAGGCAGGCTCAGCAGACAGTTCGGAAGCTGCTGTCCTCTCTTGGGGGCTTTAAGCTG
GCGCACGGACTCTTGGAGGAGCTGAAGACTGTCCTCAGTTCTCACAAGGTGCTGCCCTTA
GAGGCTTTGGTGACTGATGCTGGAGAGGTGACTGAGGCAGGCAAGGCCTACGTGCCTCCA
CGGGTCCTGCAGGAGGCTCTGTGTGTCATCTCCGGTGTGCCAGGGCTCAAGGGTGATGTC
ACCGACACTGAACAACTGGCCCAGGAAATGCTGATCATCTCCCACCACCCATCCTTAGTT
GCCGTGCAGTCTGGACTTTGGCCAGCACTTCTTGCCAGGATGAAGATCGATCCTGAAGCC
TTTATCACCAGGCACCTGGATCAGATCATTCCCAGGATGACCACACAGAGTCCCCTAAAC
CAGTCCTCCATGAATGCCATGGGCTCCCTTTCCGTCCTGTCGCCGGACCGGGTCCTCCCA
CAGCTCATCAGCACCATCACTGCCTCCGTGCAGAACCCTGCACTGCGCCTGGTGACGCGG
GAGGAGTTTGCCATTATGCAGACCCCTGCTGGGGAGCTGTATGACAAATCCATCATTCAG
AGTGCCCAGCAGGACAGCATAAAAAAGGCCAACATGAAGCGAGAGAACAAAGCTTATTCC
TTCAAAGAGCAGATCATCGAGCTGGAGCTGAAGGAGGAGATAAAGAAGAAGAAAGGCATC
AAAGAGGAGGTGCAGCTGACCAGCAAGCAGAAGGAGATGCTGCAGGCCCAGCTAGACAGG
GAGGCGCAGGTCCGGAGGCGGCTGCAGGAGCTGGATGGGGAGCTGGAGGCGGCGCTTGGA
CTGCTGGACATCATCCTGGCCAAGAACCCGTCCGGCCTGACCCAGTACATCCCTGTTTTG
GTCGACTCTTTTCTGCCCTTGCTGAAGTCTCCCCTGGCTGCTCCCAGGATCAAGAACCCC
TTCTTGTCCTTGGCTGCCTGTGTCATGCCCTCTAGGCTCAAGGCTTTGGGCACTTTGGTG
AGCCACGTGACCCTGCGCCTGCTGAAGCCAGAGTGTGTCCTGGATAAGTCCTGGTGCCAG
GAAGAGCTGTCGGTGGCTGTGAAGAGGGCGGTGATGCTGCTGCACACCCACACCATCACC
AGCAGGGTGGGCAAGGGGGAGCCAGGTGCTGCGCCCTTGTCCGCGCCAGCCTTCTCCTTA
GTCTTCCCGTTTCTGAAGATGGTGCTGACGGAGATGCCCCACCACAGTGAGGAGGAGGAG
GAGTGGATGGCCCAGATTCTTCAGATCCTCACTGTCCAAGCCCAGCTGAGGGCCTCCCCC
AACACCCCACCCGGGCGGGTGGACGAGAATGGCCCGGAGTTGCTGCCTCGCGTGGCCATG
CTGCGTCTTCTGACTTGGGTGATCGGGACGGGCTCGCCTCGCTTACAGGTTCTGGCTTCA
GACACCCTGACCACCCTGTGTGCCAGCAGCAGTGGTGATGATGGCTGTGCCTTTGCAGAG
CAGGAGGAGGTGGACGTGCTGCTCTGTGCCTTGCAGTCCCCGTGTGCCAGCGTGCGGGAA
ACCGTGCTCCGGGGGCTGATGGAACTCCACATGGTATTGCCAGCACCTGATACTGATGAG
AAGAATGGCCTGAACCTTCTGCGGAGACTCTGGGTGGTCAAGTTTGACAAGGAGGAGGAG
ATCCGGAAGCTGGCTGAGAGGCTCTGGTCAATGATGGGCCTAGACCTGCAGCCAGACCTC
TGCTCCTTGCTGATTGACGACGTGATCTATCATGAGGCGGCTGTAAGGCAGGCAGGGGCC
GAAGCCCTCTCCCAAGCAGTGGCACGTTACCAGCGGCAGGCGGCGGAGGTTATGGGCAGG
CTCATGGAGATTTACCAGGAAAAGCTCTACCGGCCGCCCCCAGTGCTGGATGCTTTGGGA
CGAGTTATTTCAGAATCTCCTCCAGATCAGTGGGAAGCCAGGTGTGGCTTGGCGTTGGCC
CTCAACAAGCTCTCCCAGTATTTGGACAGCTCTCAGGTGAAGCCACTCTTTCAGTTTTTT
GTCCCTGATGCCCTCAATGACCGACACCCAGATGTCCGGAAGTGCATGTTGGATGCAGCC
CTCGCAACGCTCAACACTCATGGGAAGGAGAACGTCAACTCGCTGTTGCCAGTATTCGAG
GAGTTCCTGAAGAACGCGCCCAATGATGCCAGCTATGATGCTGTGCGACAGAGTGTGGTG
GTCCTGATGGGCTCTCTGGCCAAGCACCTGGACAAGAGTGACCCCAAAGTGAAGCCCATT
GTTGCCAAGCTCATCGCTGCCCTCTCCACCCCCTCCCAGCAGGTCCAGGAGTCCGTAGCC
AGCTGCTTGCCACCCCTTGTGCCAGCCATCAAGGAGGATGCTGGAGGGATGATCCAGAGG
CTTATGCAGCAGCTGCTGGAGTCAGACAAGTACGCAGAGCGCAAAGGGGCCGCCTATGGC
CTGGCGGGCCTGGTGAAGGGCCTGGGCATCCTCTCGCTGAAGCAACAGGAGATGATGGCG
GCACTGACTGATGCCATCCAAGATAAGAAGAACTTCCGCCGGCGAGAGGGAGCCCTCTTT
GCCTTCGAGATGCTCTGCACCATGCTGGGGAAACTTTTTGAGCCGTATGTGGTTCACGTG
CTGCCCCATCTGCTCCTGTGCTTTGGGGATGGAAACCAGTATGTGCGTGAGGCTGCAGAT
GACTGTGCCAAGGCTGTGATGAGCAACTTGAGTGCTCACGGGGTGAAGCTGGTGCTCCCC
TCCTTACTGGCTGCCCTGGAGGAGGAATCGTGGCGGACCAAAGCTGGGTCAGTGGAGCTT
CTTGGGGCAATGGCGTACTGTGCTCCTAAGCAGCTGTCATCCTGTCTACCCAACATTGTG
CCCAAGCTTACGGAGGTGCTGACCGACTCCCATGTCAAAGTCCAGAAGGCTGGACAGCAG
GCGCTCAGGCAGATCGGCTCCGTTATCAGGAACCCGGAGATCCTGGCCATTGCTCCAGTC
CTCCTGGATGCCCTGACGGATCCCTCCAGGAAGACCCAGAAGTGCTTGCAGACCCTGCTG
GACACCAAGTTTGTCCACTTCATTGATGCCCCATCCCTGGCCCTCATCATGCCCATTGTC
CAGAGAGCCTTCCAGGACCGTTCCACGGACACGCGGAAGATGGCAGCCCAGATTATTGGC
AACATGTACTCCCTGACAGACCAGAAGGACTTGGCTCCGTACCTGCCCAGCGTGACGCCT
GGCCTGAAAGCATCGCTTTTGGACCCTGTGCCTGAGGTGCGGACCGTATCTGCAAAGGCC
CTTGGGGCCATGGTGAAGGGCATGGGGGAGTCGTGCTTTGAGGACTTGCTGCCGTGGCTG
ATGGAGACACTGACCTATGAGCAGAGCTCTGTGGATCGCTCAGGCGCTGCACAGGGGTTG
GCTGAGGTCATGGCCGGTTTGGGGGTGGAGAAGTTGGAGAAGTTGATGCCAGAAATCGTG
GCTACAGCCAGCAAAGTGGACATTGCACCCCATGTCCGAGATGGCTACATTATGATGTTT
AACTACCTGCCCATCACCTTTGGAGACAAGTTTACTCCTTATGTGGGGCCCATCATCCCC
TGTATCCTCAAAGCTCTTGCTGATGAGAATGAGTTTGTGCGTGACACCGCCCTGCGCGCG
GGCCAGCGGGTTATCTCCATGTACGCTGAGACAGCCATCGCCCTGCTGCTGCCCCAGCTA
GAGCAAGGCCTCTTTGATGACCTTTGGAGAATCAGGTTCAGCTCTGTTCAGCTCCTTGGG
GATCTCCTGTTTCACATCTCAGGAGTCACTGGGAAGATGACCACAGAAACTGCCTCTGAG
GATGATAACTTTGGAACTGCCCAGTCCAACAAGGCGATCATCACTGCCCTGGGGGTAGAG
CGGCGGAACCGGGTGTTGGCAGGGCTGTACATGGGCCGCTCAGACACCCAGCTGGTGGTG
CGGCAGGCGTCCCTGCATGTCTGGAAGATTGTTGTCTCCAATACCCCCCGCACCTTGCGT
GAGATCCTACCCACTCTCTTTGGGCTCCTGCTGGGTTTCCTGGCCAGCACGTGTGCAGAT
AAGAGAACGATTGCAGCGAGAACATTGGGAGATCTTGTGCGGAAGTTAGGGGAGAAAATC
CTCCCCGAGATCATCCCCATCCTTGAGGAAGGCCTGAGGTCTCAGAAGAGCGATGAGAGG
CAGGGTGTGTGCATTGGCCTAAGTGAGATCATGAAGTCCACCAGCCGGGATGCCGTGCTG
TATTTCTCTGAATCCCTCGTGCCCACGGCAAGGAAGGCTTTGTGTGACCCACTGGAGGAG
GTCAGAGAGGCGGCAGCCAAGACTTTCGAGCAGCTGCATTCCACCATCGGCCACCAGGCT
CTGGAGGACATTCTCCCATTTTTACTAAAGCAGCTGGATGACGAGGAGGTGTCAGAGTTT
GCCTTGGATGGTCTGAAGCAAGTCATGGCTATTAAGAGTCGTGTGGTGCTGCCCTACCTT
GTGCCCAAGCTGACAACGCCACCTGTCAACACCCGGGTGCTGGCTTTCCTTTCGTCAGTG
GCTGGTGATGCCCTCACCCGTCATCTTGGCGTGATCCTCCCAGCGGTCATGCTGGCCCTG
AAGGAAAAGCTTGGGACCCCAGATGAGCAGCTGGAGATGGCCAATTGTCAGGCTGTGATC
CTCTCCGTAGAGGATGACACAGGGCACCGGATCATCATCGAGGATCTGCTGGAGGCCACC
CGCAGCCCTGAGGTGGGCATGAGGCAAGCTGCTGCCATCATCCTCAACATCTACTGTTCC
CGCTCAAAGGCTGACTACACCAGCCACCTGCGGAGCCTGGTCTCGGGCCTGATCCGCCTC
TTCAATGACTCCAGCCCTGTGGTTCTGGAGGAGAGCTGGGATGCCCTAAATGCCATCACT
AAGAAGCTGGATGCTGGCAACCAGTTGGCACTCATTGAAGAGCTGCACAAGGAAATCCGG
CTCATAGGGAACGAGAGCAAAGGCGAGCATGTGCCAGGATTCTGCCTCCCGAAGAAGGGA
GTGACCTCCATCCTTCCAGTGTTGCGGGAAGGAGTCCTGACTGGCAGCCCTGAGCAGAAG
GAGGAGGCAGCCAAAGCCTTAGGCTTGGTAATCCGCCTGACCTCGGCTGACGCCCTGAGG
CCCTCCGTGGTCAGCATCACTGGCCCTCTGATCCGCATCCTGGGGGACAGGTTCAGCTGG
AATGTGAAGGCGGCTCTGCTCGAGACACTCAGCCTCTTGTTGGCTAAGGTTGGGATTGCC
CTGAAGCCCTTCCTGCCCCAGCTGCAGACCACTTTCACCAAAGCCCTGCAGGACTCCAAC
CGGGGGGTGCGCCTGAAGGCCGCAGATGCTCTGGGGAAGCTCATTTCCATCCACATTAAG
GTGGACCCCCTCTTCACAGAGCTGCTCAATGGCATCCGCGCCATGGAGGACCCAGGTGTC
AGGGACACCATGCTGCAGGCCCTGAGGTTTGTGATTCAGGGAGCAGGGGCCAAAGTGGAT
GCCGTCATCCGGAAAAACATCGTCTCACTCCTGCTGAGCATGCTGGGACACGATGAGGAC
AACACTCGCATCTCCTCAGCCGGGTGCCTAGGGGAACTGTGTGCCTTTTTGACTGAAGAG
GAGCTTAGTGCCGTTCTACAGCAGTGCTTGCTGGCGGACGTGTCCGGCATTGACTGGATG
GTTCGGCACGGGCGGAGCCTGGCACTTTCCGTGGCTGTGAATGTGGCTCCTGGCAGACTT
TGTGCCGGCAGATATAGCAGTGATGTTCAGGAAATGATCCTGAGCAGTGCCACGGCGGAC
AGGATCCCCATTGCGGTGAGCGGGGTCCGGGGCATGGGCTTTCTCATGAGACACCACATC
GAGACAGGCGGAGGGCAGTTGCCGGCCAAACTTTCCAGCCTGTTCGTTAAGTGTCTGCAG
AACCCATCCAGCGACATCAGGCTGGTGGCTGAGAAGATGATCTGGTGGGCAAATAAGGAC
CCACTGCCTCCCCTGGACCCCCAGGCCATCAAGCCCATCCTGAAGGCTCTTCTTGACAAC
ACCAAGGATAAGAACACCGTGGTCAGGGCCTACAGCGACCAGGCAATTGTCAACCTCCTC
AAGATGCGGCAGGGTGAAGAGGTGTTTCAGTCCCTCTCCAAGATCCTGGATGTGGCCAGT
TTGGAGGTGCTGAACGAGGTTAACCGAAGGTCCCTGAAGAAGCTGGCCAGCCAGGCCGAC
TCCACGGAGCAGGTGGACGACACCATCCTGACATGA
GenBank Gene IDNot Available
GeneCard IDNot Available
GenAtlas IDNot Available
HGNC IDHGNC:4199
Chromosome Location12
LocusNot Available
References
  1. Nagase T, Seki N, Ishikawa K, Ohira M, Kawarabayasi Y, Ohara O, Tanaka A, Kotani H, Miyajima N, Nomura N: Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain. DNA Res. 1996 Oct 31;3(5):321-9, 341-54. 9039502
  2. Nakajima D, Okazaki N, Yamakawa H, Kikuno R, Ohara O, Nagase T: Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones. DNA Res. 2002 Jun 30;9(3):99-106. 12168954
  3. Scherer SE, Muzny DM, Buhay CJ, Chen R, Cree A, Ding Y, Dugan-Rocha S, Gill R, Gunaratne P, Harris RA, Hawes AC, Hernandez J, Hodgson AV, Hume J, Jackson A, Khan ZM, Kovar-Smith C, Lewis LR, Lozado RJ, Metzker ML, Milosavljevic A, Miner GR, Montgomery KT, Morgan MB, Nazareth LV, Scott G, Sodergren E, Song XZ, Steffen D, Lovering RC, Wheeler DA, Worley KC, Yuan Y, Zhang Z, Adams CQ, Ansari-Lari MA, Ayele M, Brown MJ, Chen G, Chen Z, Clerc-Blankenburg KP, Davis C, Delgado O, Dinh HH, Draper H, Gonzalez-Garay ML, Havlak P, Jackson LR, Jacob LS, Kelly SH, Li L, Li Z, Liu J, Liu W, Lu J, Maheshwari M, Nguyen BV, Okwuonu GO, Pasternak S, Perez LM, Plopper FJ, Santibanez J, Shen H, Tabor PE, Verduzco D, Waldron L, Wang Q, Williams GA, Zhang J, Zhou J, Allen CC, Amin AG, Anyalebechi V, Bailey M, Barbaria JA, Bimage KE, Bryant NP, Burch PE, Burkett CE, Burrell KL, Calderon E, Cardenas V, Carter K, Casias K, Cavazos I, Cavazos SR, Ceasar H, Chacko J, Chan SN, Chavez D, Christopoulos C, Chu J, Cockrell R, Cox CD, Dang M, Dathorne SR, David R, Davis CM, Davy-Carroll L, Deshazo DR, Donlin JE, D'Souza L, Eaves KA, Egan A, Emery-Cohen AJ, Escotto M, Flagg N, Forbes LD, Gabisi AM, Garza M, Hamilton C, Henderson N, Hernandez O, Hines S, Hogues ME, Huang M, Idlebird DG, Johnson R, Jolivet A, Jones S, Kagan R, King LM, Leal B, Lebow H, Lee S, LeVan JM, Lewis LC, London P, Lorensuhewa LM, Loulseged H, Lovett DA, Lucier A, Lucier RL, Ma J, Madu RC, Mapua P, Martindale AD, Martinez E, Massey E, Mawhiney S, Meador MG, Mendez S, Mercado C, Mercado IC, Merritt CE, Miner ZL, Minja E, Mitchell T, Mohabbat F, Mohabbat K, Montgomery B, Moore N, Morris S, Munidasa M, Ngo RN, Nguyen NB, Nickerson E, Nwaokelemeh OO, Nwokenkwo S, Obregon M, Oguh M, Oragunye N, Oviedo RJ, Parish BJ, Parker DN, Parrish J, Parks KL, Paul HA, Payton BA, Perez A, Perrin W, Pickens A, Primus EL, Pu LL, Puazo M, Quiles MM, Quiroz JB, Rabata D, Reeves K, Ruiz SJ, Shao H, Sisson I, Sonaike T, Sorelle RP, Sutton AE, Svatek AF, Svetz LA, Tamerisa KS, Taylor TR, Teague B, Thomas N, Thorn RD, Trejos ZY, Trevino BK, Ukegbu ON, Urban JB, Vasquez LI, Vera VA, Villasana DM, Wang L, Ward-Moore S, Warren JT, Wei X, White F, Williamson AL, Wleczyk R, Wooden HS, Wooden SH, Yen J, Yoon L, Yoon V, Zorrilla SE, Nelson D, Kucherlapati R, Weinstock G, Gibbs RA: The finished DNA sequence of human chromosome 12. Nature. 2006 Mar 16;440(7082):346-51. 16541075
  4. Gerhard DS, Wagner L, Feingold EA, Shenmen CM, Grouse LH, Schuler G, Klein SL, Old S, Rasooly R, Good P, Guyer M, Peck AM, Derge JG, Lipman D, Collins FS, Jang W, Sherry S, Feolo M, Misquitta L, Lee E, Rotmistrovsky K, Greenhut SF, Schaefer CF, Buetow K, Bonner TI, Haussler D, Kent J, Kiekhaus M, Furey T, Brent M, Prange C, Schreiber K, Shapiro N, Bhat NK, Hopkins RF, Hsie F, Driscoll T, Soares MB, Casavant TL, Scheetz TE, Brown-stein MJ, Usdin TB, Toshiyuki S, Carninci P, Piao Y, Dudekula DB, Ko MS, Kawakami K, Suzuki Y, Sugano S, Gruber CE, Smith MR, Simmons B, Moore T, Waterman R, Johnson SL, Ruan Y, Wei CL, Mathavan S, Gunaratne PH, Wu J, Garcia AM, Hulyk SW, Fuh E, Yuan Y, Sneed A, Kowis C, Hodgson A, Muzny DM, McPherson J, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madari A, Young AC, Wetherby KD, Granite SJ, Kwong PN, Brinkley CP, Pearson RL, Bouffard GG, Blakesly RW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Griffith M, Griffith OL, Krzywinski MI, Liao N, Morin R, Palmquist D, Petrescu AS, Skalska U, Smailus DE, Stott JM, Schnerch A, Schein JE, Jones SJ, Holt RA, Baross A, Marra MA, Clifton S, Makowski KA, Bosak S, Malek J: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Genome Res. 2004 Oct;14(10B):2121-7. 15489334
  5. Marton MJ, Vazquez de Aldana CR, Qiu H, Chakraburtty K, Hinnebusch AG: Evidence that GCN1 and GCN20, translational regulators of GCN4, function on elongating ribosomes in activation of eIF2alpha kinase GCN2. Mol Cell Biol. 1997 Aug;17(8):4474-89. 9234705
  6. Daub H, Olsen JV, Bairlein M, Gnad F, Oppermann FS, Korner R, Greff Z, Keri G, Stemmann O, Mann M: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle. Mol Cell. 2008 Aug 8;31(3):438-48. doi: 10.1016/j.molcel.2008.07.007. 18691976
  7. Gauci S, Helbig AO, Slijper M, Krijgsveld J, Heck AJ, Mohammed S: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach. Anal Chem. 2009 Jun 1;81(11):4493-501. doi: 10.1021/ac9004309. 19413330
  8. Mayya V, Lundgren DH, Hwang SI, Rezaul K, Wu L, Eng JK, Rodionov V, Han DK: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. Sci Signal. 2009 Aug 18;2(84):ra46. doi: 10.1126/scisignal.2000007. 19690332
  9. Bienvenut WV, Sumpton D, Martinez A, Lilla S, Espagne C, Meinnel T, Giglione C: Comparative large scale characterization of plant versus mammal proteins reveals similar and idiosyncratic N-alpha-acetylation features. Mol Cell Proteomics. 2012 Jun;11(6):M111.015131. doi: 10.1074/mcp.M111.015131. Epub 2012 Jan 5. 22223895
  10. Van Damme P, Lasa M, Polevoda B, Gazquez C, Elosegui-Artola A, Kim DS, De Juan-Pardo E, Demeyer K, Hole K, Larrea E, Timmerman E, Prieto J, Arnesen T, Sherman F, Gevaert K, Aldabe R: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB. Proc Natl Acad Sci U S A. 2012 Jul 31;109(31):12449-54. doi: 10.1073/pnas.1210303109. Epub 2012 Jul 18. 22814378
  11. Bian Y, Song C, Cheng K, Dong M, Wang F, Huang J, Sun D, Wang L, Ye M, Zou H: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome. J Proteomics. 2014 Jan 16;96:253-62. doi: 10.1016/j.jprot.2013.11.014. Epub 2013 Nov 22. 24275569
  12. Vaca Jacome AS, Rabilloud T, Schaeffer-Reiss C, Rompais M, Ayoub D, Lane L, Bairoch A, Van Dorsselaer A, Carapito C: N-terminome analysis of the human mitochondrial proteome. Proteomics. 2015 Jul;15(14):2519-24. doi: 10.1002/pmic.201400617. Epub 2015 Jun 8. 25944712
  13. Burkard TR, Planyavsky M, Kaupe I, Breitwieser FP, Burckstummer T, Bennett KL, Superti-Furga G, Colinge J: Initial characterization of the human central proteome. BMC Syst Biol. 2011 Jan 26;5:17. doi: 10.1186/1752-0509-5-17. 21269460