5-hydroxytryptamine receptor 3C
Name | 5-hydroxytryptamine receptor 3C |
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Synonyms |
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Gene Name | HTR3C |
Organism | Human |
Amino acid sequence | >lcl|BSEQ0017548|5-hydroxytryptamine receptor 3C MEGGWPARQSALLCLTVSLLLQGRGDAFTINCSGFDQHGVDPAVFQAVFDRKAFRPFTNY SIPTRVNISFTLSAILGVDAQLQLLTSFLWMDLVWDNPFINWNPKECVGINKLTVLAENL WLPDIFIVESMDVDQTPSGLTAYISSEGRIKYDKPMRVTSICNLDIFYFPFDQQNCTFTF SSFLYTVDSMLLGMDKEVWEITDTSRKVIQTQGEWELLGINKATPKMSMGNNLYDQIMFY VAIRRRPSLYIINLLVPSSFLVAIDALSFYLPAESENRAPFKITLLLGYNVFLLMMNDLL PASGTPLISVYFALCLSLMVVSLLETVFITYLLHVATTQPPPMPRWLHSLLLHCTSPGRC CPTAPQKGNKGLGLTLTHLPGPKEPGELAGKKLGPRETEPDGGSGWTKTQLMELWVQFSH AMDTLLFRLYLLFMASSILTVIVLWNT |
Number of residues | 447 |
Molecular Weight | 50219.07 |
Theoretical pI | Not Available |
GO Classification | Functions
Processes
Components
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General Function | Serotonin-activated cation-selective channel activity |
Specific Function | This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor is a ligand-gated ion channel, which when activated causes fast, depolarizing responses. It is a cation-specific, but otherwise relatively nonselective, ion channel. |
Pfam Domain Function | |
Transmembrane Regions | 249-269 283-303 307-329 425-445 |
GenBank Protein ID | Not Available |
UniProtKB ID | Q8WXA8 |
UniProtKB Entry Name | 5HT3C_HUMAN |
Cellular Location | Cell membrane |
Gene sequence | >lcl|BSEQ0017549|5-hydroxytryptamine receptor 3C (HTR3C) ATGGAAGGAGGGTGGCCTGCAAGGCAGAGTGCCCTCCTCTGCCTCACTGTCAGTCTTCTG CTTCAAGGAAGAGGCGACGCTTTTACCATCAATTGCTCAGGCTTTGACCAGCATGGGGTT GACCCTGCTGTCTTCCAAGCAGTGTTTGACAGAAAGGCCTTCCGTCCATTCACCAACTAC AGCATCCCTACCCGTGTCAACATCTCCTTCACCCTGTCTGCCATCCTGGGAGTGGATGCA CAGCTCCAGCTGCTGACATCATTCCTGTGGATGGATTTGGTATGGGACAATCCTTTCATT AATTGGAACCCAAAAGAGTGTGTTGGCATCAATAAACTCACAGTATTAGCTGAAAACCTG TGGCTCCCAGACATCTTCATCGTGGAATCCATGGATGTGGATCAGACGCCTTCCGGTCTC ACTGCCTATATCAGCAGTGAAGGTCGAATTAAGTATGATAAGCCAATGAGGGTGACCAGC ATCTGTAACCTGGACATCTTCTACTTCCCTTTTGACCAACAGAACTGTACCTTCACCTTC AGTTCTTTCCTCTACACAGTGGACAGCATGCTGCTGGGCATGGACAAGGAGGTGTGGGAG ATCACAGACACGTCTCGCAAAGTCATCCAAACCCAGGGGGAGTGGGAGCTCTTGGGCATC AACAAGGCCACCCCAAAGATGTCCATGGGCAACAACCTATATGACCAGATCATGTTTTAT GTGGCCATCAGGCGCAGGCCAAGCCTCTACATCATAAACCTGCTGGTGCCCAGTAGCTTT CTGGTTGCCATTGATGCCCTCAGCTTCTACCTGCCAGCAGAGAGCGAGAATCGTGCCCCA TTCAAGATAACACTTCTGCTGGGCTACAACGTCTTCCTGCTCATGATGAATGACTTGCTC CCTGCCAGTGGCACCCCCCTCATCAGTGTCTACTTCGCCCTGTGCCTGTCCCTGATGGTG GTCAGCCTGCTGGAGACCGTCTTCATTACCTACCTGCTGCACGTGGCCACCACCCAGCCC CCACCCATGCCTAGGTGGCTTCACTCCCTGCTGCTCCACTGCACCAGCCCAGGGAGATGC TGTCCCACTGCGCCCCAGAAGGGAAATAAGGGCCTGGGTCTCACCCTCACCCACCTGCCT GGCCCAAAGGAGCCGGGGGAGTTAGCAGGGAAGAAGCTGGGACCCAGAGAGACCGAGCCA GATGGGGGCTCAGGATGGACAAAGACCCAGCTAATGGAGCTGTGGGTGCAGTTCAGCCAC GCGATGGACACCCTGCTCTTCCGCCTCTACCTGCTCTTCATGGCCTCCTCCATCCTTACT GTCATTGTCCTCTGGAACACCTAG |
GenBank Gene ID | Not Available |
GeneCard ID | Not Available |
GenAtlas ID | Not Available |
HGNC ID | HGNC:24003 |
Chromosome Location | 3 |
Locus | Not Available |
References |
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