NameLethal(3)malignant brain tumor-like protein 4
Synonyms
  • H-l(3)mbt-like protein 4
Gene NameL3MBTL4
OrganismHuman
Amino acid sequence
>lcl|BSEQ0009814|Lethal(3)malignant brain tumor-like protein 4
MKQPNRKRKLNMDSKERLDQDGRLEQAEEEKKPKDSTTPLSHVPSAAAQGAWSWEWYLKE
QKAVAAPVELFSKDQSFPEHENGFQIGMRLEGIDPRHPSVFCVLSVAEVCGYRLRLHFDG
YLSCYDFWTNAGSPDIHPVGWCEKTKHELHIPKGYRKDKFVWMDYLKACKLQNAPKKLFR
NRSPNGPMSKEFQVGMKLEAVDRKNPSLVCVATIADIVEDRLLVHFDNWDDSYDYWCDVN
SPYVQPVGWCQENGRTLIAPQGYPNPENFSWTEYLEATQTNAVPAKVFKMRLPHGFLPNM
KLEVVDKRNPRLIRVATIVDVDDQRVKVHFDGWDHKYDYWVEADSPDIHPIGWCDVTGHP
LEVPQRTNDLKILPGQAVCPTPGCRGIGHIRGPRYSGHHSAFGCPYSDMNLKKEATLHDR
LREQTQANLESDSSHSKSKSLCSLNFNGKHEKVNSQPRLVQQAKCLKIKGKEDIDLDNLF
RVLVLHPRGLEYSVEQAQQVLHQSVSMSTVSAHPFRDLPLGREQHCKLLPGVADIRASQV
ARWTVDEVAEFVQSLLGCEEHAKCFKKEQIDGKAFLLLTQTDIVKVMKIKLGPALKIYNS
ILMFRHSQELPEEDIASGQEVRG
Number of residues623
Molecular Weight71121.56
Theoretical pINot Available
GO Classification
Functions
  • zinc ion binding
  • transcription factor activity, sequence-specific DNA binding
Processes
  • transcription, DNA-templated
  • chromatin modification
Components
  • nucleus
General FunctionZinc ion binding
Specific FunctionPutative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility (By similarity).
Pfam Domain Function
Transmembrane RegionsNot Available
GenBank Protein IDNot Available
UniProtKB IDQ8NA19
UniProtKB Entry NameLMBL4_HUMAN
Cellular LocationNucleus
Gene sequence
>lcl|BSEQ0013931|Lethal(3)malignant brain tumor-like protein 4 (L3MBTL4)
ATGAAACAGCCCAACAGGAAAAGGAAGCTTAATATGGATTCCAAAGAGCGTTTGGATCAG
GACGGACGCTTGGAGCAAGCTGAAGAGGAAAAGAAGCCCAAGGATAGCACAACCCCTTTG
AGTCACGTCCCTTCAGCGGCTGCACAGGGAGCATGGTCTTGGGAGTGGTACTTGAAAGAA
CAGAAGGCTGTCGCAGCACCTGTTGAGCTGTTTTCCAAGGATCAGTCCTTTCCAGAGCAT
GAAAATGGTTTTCAGATTGGAATGAGATTAGAAGGCATTGATCCCCGACATCCATCGGTA
TTCTGTGTGCTTTCTGTAGCGGAGGTTTGTGGTTACCGTCTAAGACTTCATTTTGATGGT
TATTTAAGTTGCTATGATTTTTGGACCAATGCTGGTTCCCCTGACATTCATCCAGTAGGA
TGGTGTGAAAAGACCAAACATGAACTGCACATCCCTAAGGGTTATAGAAAAGATAAATTT
GTTTGGATGGATTACTTGAAGGCCTGCAAATTGCAAAATGCTCCAAAGAAATTATTCAGA
AACAGAAGTCCTAATGGGCCAATGTCTAAAGAATTTCAGGTTGGAATGAAGCTGGAGGCC
GTGGACAGGAAGAACCCTTCCTTGGTGTGTGTGGCGACCATAGCAGATATTGTTGAAGAT
CGCTTACTAGTGCATTTTGACAACTGGGATGATAGTTACGATTACTGGTGCGATGTTAAT
AGCCCTTATGTCCAGCCAGTTGGTTGGTGTCAGGAGAATGGAAGAACTCTGATAGCACCC
CAAGGTTATCCCAATCCAGAAAATTTTTCCTGGACAGAATACCTGGAAGCTACTCAAACC
AATGCAGTTCCTGCCAAAGTTTTTAAAATGAGGTTGCCTCATGGTTTTCTGCCAAATATG
AAACTTGAAGTTGTGGATAAACGGAACCCCAGGTTAATTCGTGTTGCTACGATTGTAGAT
GTTGATGACCAAAGAGTAAAGGTTCATTTTGATGGTTGGGACCATAAGTATGACTACTGG
GTGGAGGCAGACAGCCCTGATATCCACCCGATCGGATGGTGTGATGTCACAGGGCATCCA
CTGGAAGTGCCACAGCGAACGAATGACCTGAAGATCCTTCCAGGTCAAGCTGTCTGTCCT
ACTCCCGGGTGCCGAGGAATAGGCCATATCCGTGGTCCACGTTATTCGGGACATCACAGT
GCTTTTGGCTGCCCGTATTCAGACATGAACTTGAAAAAGGAGGCAACACTTCACGATCGT
TTGAGAGAACAAACACAGGCAAATTTGGAATCAGACTCTTCACATTCAAAATCAAAAAGC
CTCTGTAGTTTGAACTTCAATGGAAAACATGAAAAGGTGAACAGTCAGCCCAGACTTGTA
CAGCAGGCAAAGTGTTTGAAAATCAAAGGAAAAGAAGATATTGACTTGGATAATCTCTTC
AGAGTGCTTGTGCTGCATCCCAGAGGTTTGGAATACTCGGTGGAGCAGGCGCAGCAGGTG
CTTCACCAGTCAGTGTCCATGTCCACGGTGTCAGCCCACCCTTTTCGGGACCTTCCCCTC
GGCAGGGAGCAACACTGCAAGTTGCTTCCAGGCGTGGCTGACATCCGGGCCAGCCAAGTG
GCACGTTGGACTGTGGATGAGGTGGCTGAGTTTGTACAGTCTCTTCTGGGCTGTGAAGAG
CATGCCAAGTGCTTTAAGAAAGAGCAGATCGATGGCAAAGCCTTCCTGCTTCTGACACAG
ACGGACATTGTCAAAGTGATGAAGATCAAACTGGGCCCAGCACTGAAGATTTACAACTCT
ATCCTGATGTTCAGGCATTCCCAGGAACTCCCTGAAGAAGATATTGCCTCAGGCCAAGAA
GTCAGGGGATGA
GenBank Gene IDNot Available
GeneCard IDNot Available
GenAtlas IDNot Available
HGNC IDHGNC:26677
Chromosome Location18
LocusNot Available
References
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