NameHistone H2B type 3-B
Synonyms
  • H2B type 12
Gene NameHIST3H2BB
OrganismHuman
Amino acid sequence
>lcl|BSEQ0013515|Histone H2B type 3-B
MPDPSKSAPAPKKGSKKAVTKAQKKDGKKRKRGRKESYSIYVYKVLKQVHPDTGISSKAM
GIMNSFVNDIFERIASEASRLAHYNKRSTITSREVQTAVRLLLPGELAKHAVSEGTKAVT
KYTSSK
Number of residues126
Molecular Weight13908.005
Theoretical pINot Available
GO Classification
Functions
  • DNA binding
Processes
  • chromatin organization
  • nucleosome assembly
Components
  • cytoplasm
  • nucleus
  • nucleoplasm
  • nuclear nucleosome
General FunctionDna binding
Specific FunctionCore component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Pfam Domain Function
Transmembrane RegionsNot Available
GenBank Protein IDNot Available
UniProtKB IDQ8N257
UniProtKB Entry NameH2B3B_HUMAN
Cellular LocationNucleus
Gene sequence
>lcl|BSEQ0013516|Histone H2B type 3-B (HIST3H2BB)
ATGCCAGACCCGTCCAAATCGGCTCCTGCGCCCAAGAAGGGTTCTAAAAAGGCTGTCACC
AAGGCACAGAAGAAGGACGGCAAGAAGCGCAAGCGCGGCCGCAAGGAGAGCTATTCTATC
TACGTGTACAAGGTGCTGAAGCAGGTGCACCCCGACACCGGCATCTCGTCCAAGGCCATG
GGCATCATGAACTCCTTCGTCAATGACATCTTCGAGCGCATCGCCAGCGAGGCCTCCCGC
CTGGCACACTACAACAAGCGCTCCACCATCACGTCCCGCGAAGTGCAGACGGCCGTTCGC
CTGCTGCTGCCCGGCGAGCTGGCCAAGCACGCCGTGTCCGAGGGCACCAAGGCTGTCACC
AAGTACACCAGCTCCAAGTGA
GenBank Gene IDNot Available
GeneCard IDNot Available
GenAtlas IDNot Available
HGNC IDHGNC:20514
Chromosome Location1
LocusNot Available
References
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