T3DB: Kinesin-like protein KIF27

Name	Kinesin-like protein KIF27
Synonyms	Not Available
Gene Name	KIF27
Organism	Human
Amino acid sequence	>lcl\|BSEQ0009157\|Kinesin-like protein KIF27 MEEIPVKVAVRIRPLLCKEALHNHQVCVRVIPNSQQVIIGRDRVFTFDFVFGKNSTQDEV YNTCIKPLVLSLIEGYNATVFAYGQTGSGKTYTIGGGHIASVVEGQKGIIPRAIQEIFQS ISEHPSIDFNVKVSYIEVYKEDLRDLLELETSMKDLHIREDEKGNTVIVGAKECHVESAG EVMSLLEMGNAARHTGTTQMNEHSSRSHAIFTISICQVHKNMEAAEDGSWYSPRHIVSKF HFVDLAGSERVTKTGNTGERFKESIQINSGLLALGNVISALGDPRRKSSHIPYRDAKITR LLKDSLGGSAKTVMITCVSPSSSNFDESLNSLKYANRARNIRNKPTVNFSPESDRIDEME FEIKLLREALQSQQAGVSQTTQINREGSPDTNRIHSLEEQVAQLQGECLGYQCCVEEAFT FLVDLKDTVRLNEKQQHKLQEWFNMIQEVRKAVLTSFRGIGGTASLEEGPQHVTVLQLKR ELKKCQCVLAADEVVFNQKELEVKELKNQVQMMVQENKGHAVSLKEAQKVNRLQNEKIIE QQLLVDQLSEELTKLNLSVTSSAKENCGDGPDARIPERRPYTVPFDTHLGHYIYIPSRQD SRKVHTSPPMYSLDRIFAGFRTRSQMLLGHIEEQDKVLHCQFSDNSDDEESEGQEKSGTR CRSRSWIQKPDSVCSLVELSDTQDETQKSDLENEDLKIDCLQESQELNLQKLKNSERILT EAKQKMRELTINIKMKEDLIKELIKTGNDAKSVSKQYSLKVTKLEHDAEQAKVELIETQK QLQELENKDLSDVAMKVKLQKEFRKKMDAAKLRVQVLQKKQQDSKKLASLSIQNEKRANE LEQSVDHMKYQKIQLQRKLREENEKRKQLDAVIKRDQQKIKEIQLKTGQEEGLKPKAEDL DACNLKRRKGSFGSIDHLQKLDEQKKWLDEEVEKVLNQRQELEELEADLKKREAIVSKKE ALLQEKSHLENKKLRSSQALNTDSLKISTRLNLLEQELSEKNVQLQTSTAEEKTKISEQV EVLQKEKDQLQKRRHNVDEKLKNGRVLSPEEEHVLFQLEEGIEALEAAIEYRNESIQNRQ KSLRASFHNLSRGEANVLEKLACLSPVEIRTILFRYFNKVVNLREAERKQQLYNEEMKMK VLERDNMVRELESALDHLKLQCDRRLTLQQKEHEQKMQLLLHHFKEQDGEGIMETFKTYE DKIQQLEKDLYFYKKTSRDHKKKLKELVGEAIRRQLAPSEYQEAGDGVLKPEGGGMLSEE LKWASRPESMKLSGREREMDSSASSLRTQPNPQKLWEDIPELPPIHSSLAPPSGHMLGNE NKTETDDNQFTKSHSRLSSQIQVVGNVGRLHGVTPVKLCRKELRQISALELSLRRSSLGV GIGSMAADSIEVSRKPRDLKT
Number of residues	1401
Molecular Weight	160282.03
Theoretical pI	Not Available
GO Classification	Functions ATPase activity microtubule motor activity ATP binding Processes microtubule-based movement smoothened signaling pathway cilium assembly ventricular system development epithelial cilium movement Components microtubule extracellular exosome cilium kinesin complex cytoplasm
General Function	Microtubule motor activity
Specific Function	Plays an essential role in motile ciliogenesis.
Pfam Domain Function	Kinesin (PF00225 )
Transmembrane Regions	Not Available
GenBank Protein ID	Not Available
UniProtKB ID	Q86VH2
UniProtKB Entry Name	KIF27_HUMAN
Cellular Location	Cytoplasm
Gene sequence	>lcl\|BSEQ0019730\|Kinesin-like protein KIF27 (KIF27) ATGGAAGAAATACCAGTAAAAGTTGCTGTAAGAATTAGACCTCTGCTTTGCAAAGAAGCT CTTCATAATCATCAAGTTTGTGTGAGAGTTATTCCAAACAGCCAGCAAGTTATCATTGGG AGAGATAGAGTCTTCACTTTTGATTTTGTTTTTGGCAAAAATTCCACTCAAGATGAAGTT TATAACACATGTATAAAGCCCCTAGTGTTGTCACTCATTGAGGGCTATAATGCAACTGTT TTTGCCTATGGACAAACTGGATCTGGGAAGACATACACCATTGGAGGGGGCCATATTGCT TCAGTTGTGGAGGGCCAAAAGGGTATCATTCCTCGAGCTATTCAAGAAATATTTCAAAGC ATCTCTGAACATCCTAGCATTGACTTTAATGTAAAAGTATCTTATATAGAAGTGTACAAG GAAGACCTAAGAGATCTTCTAGAATTGGAGACATCCATGAAGGATCTTCACATCCGAGAA GATGAAAAAGGAAACACAGTGATTGTTGGGGCCAAGGAATGCCATGTGGAGAGTGCAGGT GAAGTGATGAGTCTTTTGGAGATGGGGAATGCAGCCAGACATACAGGTACCACTCAAATG AATGAGCACTCCAGCAGATCACATGCAATTTTTACAATCAGCATTTGTCAAGTTCATAAA AATATGGAGGCAGCTGAAGATGGATCATGGTATTCCCCTCGGCATATTGTCTCAAAGTTC CACTTTGTGGATTTGGCAGGATCAGAAAGAGTAACCAAAACGGGGAATACTGGTGAACGG TTCAAAGAATCCATTCAAATCAATAGTGGATTGCTGGCTTTAGGAAATGTAATAAGCGCT CTTGGGGACCCACGCAGGAAGAGTTCACATATTCCATATAGGGATGCTAAAATTACCCGG CTTCTGAAAGATTCTCTGGGAGGCAGTGCTAAGACTGTCATGATCACATGTGTCAGCCCC TCCTCCTCGAATTTTGATGAGTCCTTAAATTCTCTCAAATATGCCAACAGAGCACGGAAC ATTAGAAACAAACCCACTGTAAACTTCAGCCCCGAGTCAGACCGTATAGATGAAATGGAA TTTGAGATTAAATTGCTTCGAGAAGCTTTGCAAAGCCAGCAGGCTGGTGTCAGCCAAACT ACCCAGATCAATCGAGAAGGGAGTCCTGATACAAATAGGATTCATTCTCTTGAGGAGCAA GTAGCTCAGCTTCAAGGAGAATGTCTGGGTTACCAGTGTTGTGTAGAAGAAGCCTTTACC TTCCTGGTTGACCTAAAAGATACTGTCAGACTAAACGAAAAGCAGCAACACAAACTGCAG GAGTGGTTTAACATGATCCAAGAGGTCAGGAAGGCTGTCCTCACCTCATTTCGAGGAATC GGAGGCACTGCAAGTCTGGAAGAAGGACCACAGCATGTTACAGTTCTCCAGCTGAAGAGA GAGCTTAAGAAATGCCAGTGTGTGCTTGCTGCTGATGAAGTAGTATTTAATCAGAAGGAA CTGGAGGTGAAGGAACTGAAGAATCAAGTGCAGATGATGGTACAGGAAAACAAAGGGCAT GCTGTATCTTTGAAAGAAGCGCAAAAAGTGAATAGACTGCAGAATGAAAAAATAATAGAA CAACAACTTCTTGTGGATCAACTGAGTGAAGAACTAACAAAACTTAACCTGTCAGTGACT TCTTCAGCTAAAGAAAATTGTGGAGATGGGCCAGATGCCAGGATCCCTGAAAGGAGACCA TATACTGTACCATTTGATACTCATTTGGGGCATTATATTTATATCCCATCAAGACAAGAT TCCAGGAAGGTCCACACAAGTCCGCCTATGTACTCTCTGGATCGAATATTTGCTGGATTT CGAACACGAAGTCAGATGCTGTTGGGTCACATAGAAGAACAAGATAAGGTCCTCCACTGC CAATTTTCTGATAACAGTGATGATGAAGAATCAGAAGGCCAAGAGAAATCTGGAACTAGA TGTAGAAGTCGTTCATGGATTCAGAAGCCAGACTCTGTTTGTTCCCTTGTTGAATTGAGT GATACTCAGGATGAAACACAAAAGTCAGATTTGGAGAATGAAGATTTAAAGATTGATTGT CTCCAGGAGAGTCAAGAATTGAATTTGCAAAAATTAAAGAATTCAGAACGCATACTTACT GAAGCTAAACAAAAAATGAGAGAACTTACAATTAACATCAAGATGAAGGAAGATCTGATT AAAGAATTAATAAAAACAGGTAATGATGCCAAGTCTGTAAGCAAGCAGTATTCTTTGAAA GTAACAAAGCTAGAGCATGATGCAGAACAGGCAAAAGTCGAACTGATTGAAACACAAAAG CAGCTACAGGAGCTGGAAAACAAAGATCTTTCTGATGTTGCAATGAAGGTAAAATTACAG AAAGAGTTTCGTAAAAAGATGGATGCTGCAAAGCTGAGAGTTCAGGAAATACAATTAAAA ACAGGACAGGAAGAAGGTCTAAAACCGAAAGCTGAGGACCTTGATGCATGTAACTTGAAA AGGAGAAAAGGTTCGTTTGGAAGTATAGACCATCTCCAGAAATTGGATGAGCAAAAGAAA TGGTTAGATGAAGAAGTAGAGAAAGTTCTGAACCAACGCCAAGAATTAGAGGAGCTGGAA GCAGACTTAAAGAAACGGGAGGCCATAGTTTCTAAGAAGGAGGCTCTGTTACAGGAGAAG AGTCACCTGGAAAATAAGAAATTGAGATCTAGTCAGGCCTTAAACACAGATAGTTTGAAA ATATCAACTCGCCTGAACTTACTGGAACAAGAGTTGTCTGAAAAGAATGTGCAGCTCCAG ACCAGTACAGCTGAGGAGAAAACAAAGATTTCAGAACAAGTTGAAGTCCTCCAGAAAGAA AAGGATCAGCTCCAGAAACGCAGACACAATGTGGATGAAAAACTTAAAAATGGTAGAGTG TTATCACCTGAAGAAGAACATGTTCTTTTCCAACTTGAAGAAGGGATTGAAGCTTTGGAA GCTGCAATTGAATACAGGAATGAAAGTATCCAGAATCGCCAGAAGTCACTTAGAGCATCA TTCCATAACCTCTCTCGTGGTGAAGCAAATGTCTTGGAAAAGCTAGCTTGCCTGAGTCCT GTTGAGATTAGAACTATTCTTTTCAGATATTTCAATAAGGTGGTGAATTTGCGAGAAGCT GAACGGAAACAACAGTTATATAATGAAGAAATGAAAATGAAAGTTCTGGAACGGGATAAT ATGGTTCGTGAATTAGAATCTGCACTGGACCATCTAAAATTGCAGTGTGACCGGAGACTG ACCCTCCAGCAAAAGGAACACGAACAAAAGATGCAGTTGCTATTACATCATTTCAAAGAA CAAGATGGAGAAGGCATTATGGAAACTTTCAAAACATATGAAGATAAAATCCAGCAGTTG GAAAAAGATCTTTATTTCTATAAGAAAACCAGCCGGGATCATAAGAAGAAACTTAAGGAA CTGGTAGGGGAAGCAATTCGGCGGCAACTAGCACCATCAGAGTATCAAGAGGCTGGAGAT GGAGTCCTGAAGCCAGAAGGAGGAGGCATGCTTTCAGAAGAATTAAAATGGGCATCCAGA CCTGAAAGTATGAAATTAAGTGGAAGAGAAAGAGAAATGGACAGTTCAGCAAGCAGCTTA AGAACACAGCCAAATCCTCAAAAGCTCTGGGAAGATATCCCAGAATTACCTCCAATTCAT AGTTCTTTAGCACCCCCCAGTGGGCATATGTTAGGTAATGAGAATAAAACAGAAACAGAT GATAATCAGTTTACAAAATCTCACAGTCGACTGTCATCCCAAATTCAGGTTGTGGGAAAT GTGGGACGACTTCATGGTGTCACACCTGTAAAACTGTGTCGAAAAGAATTACGTCAAATT TCCGCCTTGGAACTATCATTGCGACGTTCCAGTCTTGGAGTTGGCATTGGATCAATGGCT GCTGATTCCATCGAAGTATCTAGGAAACCAAGGGACTTAAAAACTTAG
GenBank Gene ID	Not Available
GeneCard ID	Not Available
GenAtlas ID	Not Available
HGNC ID	HGNC:18632
Chromosome Location	9
Locus	Not Available
References	Oduru S, Campbell JL, Karri S, Hendry WJ, Khan SA, Williams SC: Gene discovery in the hamster: a comparative genomics approach for gene annotation by sequencing of hamster testis cDNAs. BMC Genomics. 2003 Jun 3;4(1):22. 12783626 Humphray SJ, Oliver K, Hunt AR, Plumb RW, Loveland JE, Howe KL, Andrews TD, Searle S, Hunt SE, Scott CE, Jones MC, Ainscough R, Almeida JP, Ambrose KD, Ashwell RI, Babbage AK, Babbage S, Bagguley CL, Bailey J, Banerjee R, Barker DJ, Barlow KF, Bates K, Beasley H, Beasley O, Bird CP, Bray-Allen S, Brown AJ, Brown JY, Burford D, Burrill W, Burton J, Carder C, Carter NP, Chapman JC, Chen Y, Clarke G, Clark SY, Clee CM, Clegg S, Collier RE, Corby N, Crosier M, Cummings AT, Davies J, Dhami P, Dunn M, Dutta I, Dyer LW, Earthrowl ME, Faulkner L, Fleming CJ, Frankish A, Frankland JA, French L, Fricker DG, Garner P, Garnett J, Ghori J, Gilbert JG, Glison C, Grafham DV, Gribble S, Griffiths C, Griffiths-Jones S, Grocock R, Guy J, Hall RE, Hammond S, Harley JL, Harrison ES, Hart EA, Heath PD, Henderson CD, Hopkins BL, Howard PJ, Howden PJ, Huckle E, Johnson C, Johnson D, Joy AA, Kay M, Keenan S, Kershaw JK, Kimberley AM, King A, Knights A, Laird GK, Langford C, Lawlor S, Leongamornlert DA, Leversha M, Lloyd C, Lloyd DM, Lovell J, Martin S, Mashreghi-Mohammadi M, Matthews L, McLaren S, McLay KE, McMurray A, Milne S, Nickerson T, Nisbett J, Nordsiek G, Pearce AV, Peck AI, Porter KM, Pandian R, Pelan S, Phillimore B, Povey S, Ramsey Y, Rand V, Scharfe M, Sehra HK, Shownkeen R, Sims SK, Skuce CD, Smith M, Steward CA, Swarbreck D, Sycamore N, Tester J, Thorpe A, Tracey A, Tromans A, Thomas DW, Wall M, Wallis JM, West AP, Whitehead SL, Willey DL, Williams SA, Wilming L, Wray PW, Young L, Ashurst JL, Coulson A, Blocker H, Durbin R, Sulston JE, Hubbard T, Jackson MJ, Bentley DR, Beck S, Rogers J, Dunham I: DNA sequence and analysis of human chromosome 9. Nature. 2004 May 27;429(6990):369-74. 15164053 Gerhard DS, Wagner L, Feingold EA, Shenmen CM, Grouse LH, Schuler G, Klein SL, Old S, Rasooly R, Good P, Guyer M, Peck AM, Derge JG, Lipman D, Collins FS, Jang W, Sherry S, Feolo M, Misquitta L, Lee E, Rotmistrovsky K, Greenhut SF, Schaefer CF, Buetow K, Bonner TI, Haussler D, Kent J, Kiekhaus M, Furey T, Brent M, Prange C, Schreiber K, Shapiro N, Bhat NK, Hopkins RF, Hsie F, Driscoll T, Soares MB, Casavant TL, Scheetz TE, Brown-stein MJ, Usdin TB, Toshiyuki S, Carninci P, Piao Y, Dudekula DB, Ko MS, Kawakami K, Suzuki Y, Sugano S, Gruber CE, Smith MR, Simmons B, Moore T, Waterman R, Johnson SL, Ruan Y, Wei CL, Mathavan S, Gunaratne PH, Wu J, Garcia AM, Hulyk SW, Fuh E, Yuan Y, Sneed A, Kowis C, Hodgson A, Muzny DM, McPherson J, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madari A, Young AC, Wetherby KD, Granite SJ, Kwong PN, Brinkley CP, Pearson RL, Bouffard GG, Blakesly RW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Griffith M, Griffith OL, Krzywinski MI, Liao N, Morin R, Palmquist D, Petrescu AS, Skalska U, Smailus DE, Stott JM, Schnerch A, Schein JE, Jones SJ, Holt RA, Baross A, Marra MA, Clifton S, Makowski KA, Bosak S, Malek J: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Genome Res. 2004 Oct;14(10B):2121-7. 15489334 Bechtel S, Rosenfelder H, Duda A, Schmidt CP, Ernst U, Wellenreuther R, Mehrle A, Schuster C, Bahr A, Blocker H, Heubner D, Hoerlein A, Michel G, Wedler H, Kohrer K, Ottenwalder B, Poustka A, Wiemann S, Schupp I: The full-ORF clone resource of the German cDNA Consortium. BMC Genomics. 2007 Oct 31;8:399. 17974005