NameLactase-like protein
Synonyms
  • Klotho/lactase-phlorizin hydrolase-related protein
  • KLPH
Gene NameLCTL
OrganismHuman
Amino acid sequence
>lcl|BSEQ0007839|Lactase-like protein
MKPVWVATLLWMLLLVPRLGAARKGSPEEASFYYGTFPLGFSWGVGSSAYQTEGAWDQDG
KGPSIWDVFTHSGKGKVLGNETADVACDGYYKVQEDIILLRELHVNHYRFSLSWPRLLPT
GIRAEQVNKKGIEFYSDLIDALLSSNITPIVTLHHWDLPQLLQVKYGGWQNVSMANYFRD
YANLCFEAFGDRVKHWITFSDPRAMAEKGYETGHHAPGLKLRGTGLYKAAHHIIKAHAKA
WHSYNTTWRSKQQGLVGISLNCDWGEPVDISNPKDLEAAERYLQFCLGWFANPIYAGDYP
QVMKDYIGRKSAEQGLEMSRLPVFSLQEKSYIKGTSDFLGLGHFTTRYITERNYPSRQGP
SYQNDRDLIELVDPNWPDLGSKWLYSVPWGFRRLLNFAQTQYGDPPIYVMENGASQKFHC
TQLCDEWRIQYLKGYINEMLKAIKDGANIKGYTSWSLLDKFEWEKGYSDRYGFYYVEFND
RNKPRYPKASVQYYKKIIIANGFPNPREVESWYLKALETCSINNQMLAAEPLLSHMQMVT
EIVVPTVCSLCVLITAVLLMLLLRRQS
Number of residues567
Molecular Weight65087.84
Theoretical pI8.12
GO Classification
Functions
  • hydrolase activity, hydrolyzing O-glycosyl compounds
Processes
  • carbohydrate metabolic process
Components
  • endoplasmic reticulum membrane
  • integral component of membrane
  • brush border
General FunctionHydrolase activity, hydrolyzing o-glycosyl compounds
Specific FunctionNot Available
Pfam Domain Function
Transmembrane Regions542-562
GenBank Protein ID37182579
UniProtKB IDQ6UWM7
UniProtKB Entry NameLCTL_HUMAN
Cellular LocationEndoplasmic reticulum membrane
Gene sequence
>lcl|BSEQ0019521|Lactase-like protein (LCTL)
ATGGCCAACTACTTCAGAGACTACGCCAACCTGTGCTTTGAGGCCTTTGGGGACCGTGTG
AAGCACTGGATCACGTTCAGTGATCCTCGGGCAATGGCAGAAAAAGGCTATGAGACGGGC
CACCATGCGCCGGGCCTGAAGCTCCGCGGCACCGGCCTGTACAAGGCAGCACACCACATC
ATTAAGGCCCACGCCAAAGCCTGGCATTCTTATAACACCACGTGGCGCAGCAAGCAGCAA
GGTCTGGTGGGAATTTCATTGAACTGTGACTGGGGGGAACCTGTGGACATTAGTAACCCC
AAGGACCTAGAGGCTGCCGAGAGATACCTACAGTTCTGTCTGGGCTGGTTTGCCAACCCC
ATTTATGCCGGTGACTACCCCCAAGTCATGAAGGACTACATTGGAAGAAAGAGTGCAGAG
CAAGGCCTGGAGATGTCGAGGTTACCGGTGTTCTCACTCCAGGAGAAGAGCTACATTAAA
GGCACATCCGATTTCTTGGGATTAGGTCATTTTACTACTCGGTACATCACGGAAAGGAAC
TACCCCTCCCGCCAGGGGCCCAGCTACCAGAACGATCGTGACTTGATAGAGCTGGTTGAC
CCAAACTGGCCAGATCTGGGGTCTAAATGGCTATATTCTGTGCCATGGGGATTTAGGAGG
CTCCTTAACTTTGCTCAGACTCAATACGGTGATCCTCCCATATATGTGATGGAAAATGGA
GCATCTCAAAAATTCCACTGTACTCAATTATGTGATGAGTGGAGAATTCAATACCTTAAA
GGATACATAAATGAAATGCTAAAAGCTATAAAAGATGGTGCTAATATAAAGGGGTATACT
TCCTGGTCTCTGTTGGATAAGTTTGAATGGGAGAAAGGATACTCAGATAGATATGGATTC
TACTATGTTGAATTTAACGACAGAAATAAGCCTCGCTATCCAAAGGCTTCAGTTCAATAT
TACAAGAAGATTATCATTGCCAATGGGTTTCCCAATCCAAGAGAGGTGGAAAGTTGGTAC
CTCAAAGCTTTGGAAACTTGCTCTATCAACAATCAGATGCTTGCTGCAGAGCCCTTGCTA
AGTCACATGCAAATGGTTACGGAGATCGTGGTACCCACTGTCTGCTCCCTCTGTGTCCTC
ATCACTGCTGTTCTACTAATGCTCCTCCTGAGGAGGCAGAGCTGA
GenBank Gene IDAY358729
GeneCard IDNot Available
GenAtlas IDNot Available
HGNC IDHGNC:15583
Chromosome Location15
Locus15q22.31
References
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