NameSolute carrier family 2, facilitated glucose transporter member 7
Synonyms
  • Glucose transporter type 7
  • GLUT-7
  • GLUT7
Gene NameSLC2A7
OrganismHuman
Amino acid sequence
>lcl|BSEQ0019707|Solute carrier family 2, facilitated glucose transporter member 7
MENKEAGTPPPIPSREGRLQPTLLLATLSAAFGSAFQYGYNLSVVNTPHKVFKSFYNETY
FERHATFMDGKLMLLLWSCTVSMFPLGGLLGSLLVGLLVDSCGRKGTLLINNIFAIIPAI
LMGVSKVAKAFELIVFSRVVLGVCAGISYSALPMYLGELAPKNLRGMVGTMTEVFVIVGV
FLAQIFSLQAILGNPAGWPVLLALTGVPALLQLLTLPFFPESPRYSLIQKGDEATARQAL
RRLRGHTDMEAELEDMRAEARAERAEGHLSVLHLCALRSLRWQLLSIIVLMAGQQLSGIN
AINYYADTIYTSAGVEAAHSQYVTVGSGVVNIVMTITSAVLVERLGRRHLLLAGYGICGS
ACLVLTVVLLFQNRVPELSYLGIICVFAYIAGHSIGPSPVPSVVRTEIFLQSSRRAAFMV
DGAVHWLTNFIIGFLFPSIQEAIGAYSFIIFAGICLLTAIYIYVVIPETKGKTFVEINRI
FAKRNRVKLPEEKEETIDAGPPTASPAKETSF
Number of residues512
Molecular Weight55726.915
Theoretical pINot Available
GO Classification
Functions
  • substrate-specific transmembrane transporter activity
Processes
  • transmembrane transport
  • carbohydrate transport
Components
  • integral component of membrane
  • plasma membrane
General FunctionSubstrate-specific transmembrane transporter activity
Specific FunctionHigh-affinity transporter for glucose and fructose Does not transport galactose, 2-deoxy-d-glucose and xylose.
Pfam Domain Function
Transmembrane Regions22-42 79-99 108-128 139-159 173-193 199-219 282-302 322-342 351-371 380-400 416-436 446-466
GenBank Protein IDNot Available
UniProtKB IDQ6PXP3
UniProtKB Entry NameGTR7_HUMAN
Cellular LocationMembrane
Gene sequence
>lcl|BSEQ0019708|Solute carrier family 2, facilitated glucose transporter member 7 (SLC2A7)
ATGGAGAACAAAGAGGCGGGAACCCCTCCACCCATTCCATCCAGGGAGGGGCGGCTCCAG
CCGACGCTGTTGCTGGCGACACTGAGCGCGGCCTTTGGCTCAGCCTTCCAGTACGGCTAC
AACCTCTCTGTGGTCAACACGCCGCACAAGGTCTTCAAGTCATTTTACAACGAAACCTAC
TTTGAGCGACACGCAACATTCATGGACGGGAAGCTCATGCTGCTTCTATGGTCTTGCACC
GTCTCCATGTTTCCTCTGGGCGGCCTGTTGGGGTCATTGCTCGTGGGCCTGCTGGTTGAT
AGCTGCGGCAGAAAGGGGACCCTGCTGATCAACAACATCTTTGCCATCATCCCCGCCATC
CTGATGGGAGTCAGCAAAGTGGCCAAGGCTTTTGAGCTGATCGTCTTTTCCCGAGTGGTG
CTGGGAGTCTGTGCAGGCATCTCCTACAGCGCCCTTCCCATGTACCTGGGAGAACTGGCC
CCCAAGAACCTGAGAGGCATGGTGGGAACAATGACCGAGGTTTTCGTCATCGTTGGAGTC
TTCCTAGCACAGATCTTCAGCCTCCAGGCCATCTTGGGCAACCCGGCAGGCTGGCCGGTG
CTTCTGGCGCTCACAGGGGTGCCCGCCCTGCTGCAGCTGCTGACCCTGCCCTTCTTCCCC
GAAAGCCCCCGCTACTCCCTGATTCAGAAAGGAGATGAAGCCACAGCGCGACAAGCTCTG
AGGAGGCTGAGAGGCCACACGGACATGGAGGCCGAGCTGGAGGACATGCGTGCGGAGGCC
CGGGCCGAGCGCGCCGAGGGCCACCTGTCTGTGCTGCACCTCTGTGCCCTGCGGTCCCTG
CGCTGGCAGCTCCTCTCCATCATCGTGCTCATGGCCGGCCAGCAGCTGTCGGGCATCAAT
GCGATCAACTACTATGCGGACACCATCTACACATCTGCGGGCGTGGAGGCCGCTCACTCC
CAATATGTAACGGTGGGCTCTGGCGTCGTCAACATAGTGATGACCATCACCTCGGCTGTC
CTTGTGGAGCGGCTGGGACGGCGGCACCTCCTGCTGGCCGGCTACGGCATCTGCGGCTCT
GCCTGCCTGGTGCTGACGGTGGTGCTCCTATTCCAGAACAGGGTCCCCGAGCTGTCCTAC
CTCGGCATCATCTGTGTCTTTGCCTACATCGCGGGACATTCCATTGGGCCCAGTCCTGTC
CCCTCGGTGGTGAGGACCGAGATCTTCCTGCAGTCCTCCCGGCGGGCAGCTTTCATGGTG
GACGGGGCAGTGCACTGGCTCACCAACTTCATCATAGGCTTCCTGTTCCCATCCATCCAG
GAGGCCATCGGTGCCTACAGTTTCATCATCTTTGCCGGAATCTGCCTCCTCACTGCGATT
TACATCTACGTGGTTATTCCGGAGACCAAGGGCAAAACATTTGTGGAGATAAACCGCATT
TTTGCCAAGAGAAACAGGGTGAAGCTTCCAGAGGAGAAAGAAGAAACCATTGATGCTGGG
CCTCCCACAGCCTCTCCTGCCAAGGAAACTTCCTTTTAG
GenBank Gene IDNot Available
GeneCard IDNot Available
GenAtlas IDNot Available
HGNC IDHGNC:13445
Chromosome Location1
LocusNot Available
References
  1. Li Q, Manolescu A, Ritzel M, Yao S, Slugoski M, Young JD, Chen XZ, Cheeseman CI: Cloning and functional characterization of the human GLUT7 isoform SLC2A7 from the small intestine. Am J Physiol Gastrointest Liver Physiol. 2004 Jul;287(1):G236-42. Epub 2004 Mar 19. 15033637
  2. Gregory SG, Barlow KF, McLay KE, Kaul R, Swarbreck D, Dunham A, Scott CE, Howe KL, Woodfine K, Spencer CC, Jones MC, Gillson C, Searle S, Zhou Y, Kokocinski F, McDonald L, Evans R, Phillips K, Atkinson A, Cooper R, Jones C, Hall RE, Andrews TD, Lloyd C, Ainscough R, Almeida JP, Ambrose KD, Anderson F, Andrew RW, Ashwell RI, Aubin K, Babbage AK, Bagguley CL, Bailey J, Beasley H, Bethel G, Bird CP, Bray-Allen S, Brown JY, Brown AJ, Buckley D, Burton J, Bye J, Carder C, Chapman JC, Clark SY, Clarke G, Clee C, Cobley V, Collier RE, Corby N, Coville GJ, Davies J, Deadman R, Dunn M, Earthrowl M, Ellington AG, Errington H, Frankish A, Frankland J, French L, Garner P, Garnett J, Gay L, Ghori MR, Gibson R, Gilby LM, Gillett W, Glithero RJ, Grafham DV, Griffiths C, Griffiths-Jones S, Grocock R, Hammond S, Harrison ES, Hart E, Haugen E, Heath PD, Holmes S, Holt K, Howden PJ, Hunt AR, Hunt SE, Hunter G, Isherwood J, James R, Johnson C, Johnson D, Joy A, Kay M, Kershaw JK, Kibukawa M, Kimberley AM, King A, Knights AJ, Lad H, Laird G, Lawlor S, Leongamornlert DA, Lloyd DM, Loveland J, Lovell J, Lush MJ, Lyne R, Martin S, Mashreghi-Mohammadi M, Matthews L, Matthews NS, McLaren S, Milne S, Mistry S, Moore MJ, Nickerson T, O'Dell CN, Oliver K, Palmeiri A, Palmer SA, Parker A, Patel D, Pearce AV, Peck AI, Pelan S, Phelps K, Phillimore BJ, Plumb R, Rajan J, Raymond C, Rouse G, Saenphimmachak C, Sehra HK, Sheridan E, Shownkeen R, Sims S, Skuce CD, Smith M, Steward C, Subramanian S, Sycamore N, Tracey A, Tromans A, Van Helmond Z, Wall M, Wallis JM, White S, Whitehead SL, Wilkinson JE, Willey DL, Williams H, Wilming L, Wray PW, Wu Z, Coulson A, Vaudin M, Sulston JE, Durbin R, Hubbard T, Wooster R, Dunham I, Carter NP, McVean G, Ross MT, Harrow J, Olson MV, Beck S, Rogers J, Bentley DR, Banerjee R, Bryant SP, Burford DC, Burrill WD, Clegg SM, Dhami P, Dovey O, Faulkner LM, Gribble SM, Langford CF, Pandian RD, Porter KM, Prigmore E: The DNA sequence and biological annotation of human chromosome 1. Nature. 2006 May 18;441(7091):315-21. 16710414