UDP-glucuronosyltransferase 3A1
Name | UDP-glucuronosyltransferase 3A1 |
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Synonyms |
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Gene Name | UGT3A1 |
Organism | Human |
Amino acid sequence | >lcl|BSEQ0007901|UDP-glucuronosyltransferase 3A1 MVGQRVLLLVAFLLSGVLLSEAAKILTISTLGGSHYLLLDRVSQILQEHGHNVTMLHQSG KFLIPDIKEEEKSYQVIRWFSPEDHQKRIKKHFDSYIETALDGRKESEALVKLMEIFGTQ CSYLLSRKDIMDSLKNENYDLVFVEAFDFCSFLIAEKLVKPFVAILPTTFGSLDFGLPSP LSYVPVFPSLLTDHMDFWGRVKNFLMFFSFSRSQWDMQSTFDNTIKEHFPEGSRPVLSHL LLKAELWFVNSDFAFDFARPLLPNTVYIGGLMEKPIKPVPQDLDNFIANFGDAGFVLVAF GSMLNTHQSQEVLKKMHNAFAHLPQGVIWTCQSSHWPRDVHLATNVKIVDWLPQSDLLAH PSIRLFVTHGGQNSVMEAIRHGVPMVGLPVNGDQHGNMVRVVAKNYGVSIRLNQVTADTL TLTMKQVIEDKRYKSAVVAASVILHSQPLSPAQRLVGWIDHILQTGGATHLKPYAFQQPW HEQYLIDVFVFLLGLTLGTMWLCGKLLGVVARWLRGARKVKKT |
Number of residues | 523 |
Molecular Weight | 59150.34 |
Theoretical pI | 8.35 |
GO Classification | Functions
Processes
Components
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General Function | Udp-glycosyltransferase activity |
Specific Function | UDP-glucuronosyltransferases catalyze phase II biotransformation reactions in which lipophilic substrates are conjugated with glucuronic acid to increase water solubility and enhance excretion. They are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds (By similarity). |
Pfam Domain Function |
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Transmembrane Regions | 484-504 |
GenBank Protein ID | 16552644 |
UniProtKB ID | Q6NUS8 |
UniProtKB Entry Name | UD3A1_HUMAN |
Cellular Location | Membrane |
Gene sequence | >lcl|BSEQ0019527|UDP-glucuronosyltransferase 3A1 (UGT3A1) ATGCTTCATCAGAGTGGAAAGTTTTTGATCCCAGATATTAAAGAGGAGGAAAAATCATAC CAAGTTATCAGGTGGTTTTCACCTGAAGATCATCAAAAAAGAATTAAGAAGCATTTTGAT AGCTACATAGAAACAGCATTGGATGGCAGAAAAGAATCTGAAGCCCTTGTAAAGCTAATG GAAATATTTGGGACTCAATGTAGTTATTTGCTAAGCAGAAAGGATATAATGGATTCCTTA AAGAATGAGAACTATGATCTGGTATTTGTTGAAGCATTTGATTTCTGTTCTTTCCTGATT GCTGAGAAGCTTGTGAAACCATTTGTGGCCATTCTTCCCACCACATTCGGCTCTTTGGAT TTTGGGCTACCAAGCCCCTTGTCTTATGTTCCAGTATTCCCTTCCTTGCTGACTGATCAC ATGGACTTCTGGGGCCGAGTGAAGAATTTTCTGATGTTCTTTAGTTTCTCCAGGAGCCAA TGGGACATGCAGTCTACATTTGACAACACCATCAAGGAGCATTTCCCAGAAGGCTCTAGG CCAGTTTTGTCTCATCTTCTACTGAAAGCAGAGTTGTGGTTTGTTAACTCTGATTTTGCC TTTGATTTTGCCCGGCCCCTGCTTCCCAACACTGTTTATATTGGAGGCTTGATGGAAAAA CCTATTAAACCAGTACCACAAAATGGGCAACCAGCTCTCTTCACCACCCCCAGCTTATTC TCCTCTGGAGTGTATCCTGAACCACTGAGATGGCTTTGA |
GenBank Gene ID | AK057066 |
GeneCard ID | Not Available |
GenAtlas ID | Not Available |
HGNC ID | HGNC:26625 |
Chromosome Location | 5 |
Locus | 5p13.2 |
References |
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