Glycine receptor subunit alpha-4
Name | Glycine receptor subunit alpha-4 |
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Synonyms | Not Available |
Gene Name | GLRA4 |
Organism | Human |
Amino acid sequence | >lcl|BSEQ0019716|Glycine receptor subunit alpha-4 MTTLVPATLSFLLLWTLPGQVLLRVALAKEEVKSGTKGSQPMSPSDFLDKLMGRTSGYDA RIRPNFKGPPVNVTCNIFINSFSSITKTTMDYRVNVFLRQQWNDPRLSYREYPDDSLDLD PSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLILSCLMDLKNFP MDIQTCTMQLESFGYTMKDLVFEWLEDAPAVQVAEGLTLPQFILRDEKDLGCCTKHYNTG KFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTT QSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAINFVSRQHKEFIRLRRRQRRQR LEEDIIQESRFYFRGYGLGHCLQARDGGPMEGSGIYSPQPPAPLLREGETTRKLYVD |
Number of residues | 417 |
Molecular Weight | 47727.92 |
Theoretical pI | Not Available |
GO Classification | Functions
Processes
Components
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General Function | Transmitter-gated ion channel activity |
Specific Function | The glycine receptor is a neurotransmitter-gated ion channel. Binding of glycine to its receptor increases the chloride conductance and thus produces hyperpolarization (inhibition of neuronal firing). |
Pfam Domain Function | |
Transmembrane Regions | 259-279 322-342 |
GenBank Protein ID | Not Available |
UniProtKB ID | Q5JXX5 |
UniProtKB Entry Name | GLRA4_HUMAN |
Cellular Location | Cell junction |
Gene sequence | >lcl|BSEQ0019717|Glycine receptor subunit alpha-4 (GLRA4) ATGACAACTCTTGTTCCTGCAACCCTCTCCTTCCTTCTTCTCTGGACCCTGCCAGGGCAG GTCCTCCTCAGGGTGGCCTTGGCAAAAGAGGAAGTCAAATCTGGAACCAAGGGGTCCCAG CCCATGTCCCCCTCTGATTTCCTAGACAAACTTATGGGGCGAACATCTGGATATGATGCC AGGATTCGGCCCAATTTTAAAGGCCCACCCGTGAACGTGACCTGCAACATCTTCATCAAC AGTTTCAGCTCCATCACCAAGACCACAATGGACTACCGGGTGAATGTCTTCTTGCGGCAA CAGTGGAATGACCCACGCCTGTCCTACCGAGAATATCCTGATGACTCTCTGGACCTCGAT CCCTCCATGCTGGACTCTATCTGGAAGCCAGACCTCTTCTTTGCTAATGAGAAAGGGGCC AACTTCCATGAGGTGACCACGGACAACAAGTTACTGCGCATCTTCAAGAATGGGAATGTG CTGTACAGCATCAGGCTGACCCTCATTTTGTCCTGCCTGATGGACCTCAAGAACTTCCCC ATGGACATCCAGACCTGCACGATGCAGCTTGAGAGCTTTGGCTACACCATGAAAGACCTC GTGTTTGAGTGGCTGGAAGATGCTCCTGCTGTCCAAGTGGCTGAGGGGCTGACTCTGCCC CAGTTTATCTTGCGGGATGAGAAGGATCTAGGCTGTTGTACCAAGCACTACAACACAGGG AAATTCACCTGCATCGAGGTAAAGTTTCACCTGGAACGGCAGATGGGCTACTATCTGATT CAGATGTACATCCCCAGCCTACTCATCGTCATCCTGTCCTGGGTCTCCTTCTGGATCAAC ATGGATGCTGCCCCTGCCCGTGTGGGCCTGGGCATCACCACCGTGCTCACCATGACCACC CAGAGCTCTGGCTCCCGGGCCTCTTTGCCTAAGGTGTCCTACGTGAAGGCAATCGACATC TGGATGGCTGTGTGTCTGCTCTTTGTGTTCGCTGCCTTGCTGGAGTATGCTGCCATAAAT TTTGTTTCTCGTCAGCATAAAGAATTCATACGACTTCGAAGAAGGCAGAGGCGCCAACGC TTGGAGGAAGATATCATCCAAGAAAGTCGTTTCTATTTCCGTGGCTATGGCTTGGGCCAC TGCCTGCAGGCAAGAGATGGAGGTCCAATGGAAGGTTCTGGCATTTATAGTCCCCAACCT CCAGCCCCTCTTCTAAGGGAAGGAGAAACCACGCGGAAACTCTACGTGGACTGA |
GenBank Gene ID | Not Available |
GeneCard ID | Not Available |
GenAtlas ID | Not Available |
HGNC ID | HGNC:31715 |
Chromosome Location | X |
Locus | Not Available |
References |
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