Proprotein convertase subtilisin/kexin type 7
Name | Proprotein convertase subtilisin/kexin type 7 |
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Synonyms |
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Gene Name | PCSK7 |
Organism | Human |
Amino acid sequence | >lcl|BSEQ0017837|Proprotein convertase subtilisin/kexin type 7 MPKGRQKVPHLDAPLGLPTCLWLELAGLFLLVPWVMGLAGTGGPDGQGTGGPSWAVHLES LEGDGEEETLEQQADALAQAAGLVNAGRIGELQGHYLFVQPAGHRPALEVEAIRQQVEAV LAGHEAVRWHSEQRLLRRAKRSVHFNDPKYPQQWHLNNRRSPGRDINVTGVWERNVTGRG VTVVVVDDGVEHTIQDIAPNYSPEGSYDLNSNDPDPMPHPDVENGNHHGTRCAGEIAAVP NNSFCAVGVAYGSRIAGIRVLDGPLTDSMEAVAFNKHYQINDIYSCSWGPDDDGKTVDGP HQLGKAALQHGVIAGRQGFGSIFVVASGNGGQHNDNCNYDGYANSIYTVTIGAVDEEGRM PFYAEECASMLAVTFSGGDKMLRSIVTTDWDLQKGTGCTEGHTGTSAAAPLAAGMIALML QVRPCLTWRDVQHIIVFTATRYEDRRAEWVTNEAGFSHSHQHGFGLLNAWRLVNAAKIWT SVPYLASYVSPVLKENKAIPQSPRSLEVLWNVSRMDLEMSGLKTLEHVAVTVSITHPRRG SLELKLFCPSGMMSLIGAPRSMDSDPNGFNDWTFSTVRCWGERARGTYRLVIRDVGDESF QVGILRQWQLTLYGSVWSAVDIRDRQRLLESAMSGKYLHDDFALPCPPGLKIPEEDGYTI TPNTLKTLVLVGCFTVFWTVYYMLEVYLSQRNVASNQVCRSGPCHWPHRSRKAKEEGTEL ESVPLCSSKDPDEVETESRGPPTTSDLLAPDLLEQGDWSLSQNKSALDCPHQHLDVPHGK EEQIC |
Number of residues | 785 |
Molecular Weight | 86246.44 |
Theoretical pI | Not Available |
GO Classification | Functions
Processes
Components
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General Function | Serine-type endopeptidase activity |
Specific Function | Likely to represent a ubiquitous endoprotease activity within constitutive secretory pathways and capable of cleavage at the RXXX[KR]R consensus motif. |
Pfam Domain Function | |
Transmembrane Regions | 668-688 |
GenBank Protein ID | Not Available |
UniProtKB ID | Q16549 |
UniProtKB Entry Name | PCSK7_HUMAN |
Cellular Location | Golgi apparatus |
Gene sequence | >lcl|BSEQ0017838|Proprotein convertase subtilisin/kexin type 7 (PCSK7) ATGCCGAAGGGGAGGCAGAAAGTGCCACACTTGGATGCCCCCCTGGGCCTGCCCACCTGC CTCTGGCTGGAATTAGCCGGGCTCTTCTTACTGGTTCCCTGGGTCATGGGCCTGGCAGGG ACAGGTGGGCCTGATGGCCAGGGCACAGGGGGGCCGAGCTGGGCTGTGCACCTGGAAAGC CTGGAAGGTGACGGGGAGGAAGAGACTCTGGAGCAGCAGGCGGATGCCTTGGCCCAGGCA GCAGGGCTGGTGAATGCTGGACGCATCGGAGAGCTTCAGGGGCACTACCTCTTTGTCCAG CCTGCTGGGCACAGGCCGGCCCTGGAGGTGGAGGCCATCCGGCAGCAGGTGGAGGCTGTG TTGGCTGGGCATGAAGCTGTGCGCTGGCACTCAGAGCAGAGGCTGCTAAGGCGGGCCAAG CGCAGCGTCCACTTCAACGACCCCAAGTACCCGCAGCAATGGCACCTGAATAACCGACGG AGCCCGGGCAGGGACATCAACGTGACGGGTGTGTGGGAACGCAATGTGACTGGGCGAGGG GTGACGGTGGTGGTAGTGGATGACGGAGTGGAACACACCATCCAGGACATTGCACCCAAC TATAGCCCTGAGGGTAGCTATGACCTCAACTCTAATGACCCTGACCCCATGCCCCACCCG GATGTGGAGAATGGCAACCACCATGGCACGCGATGTGCAGGAGAGATCGCGGCTGTGCCC AACAACAGCTTCTGTGCCGTGGGCGTGGCCTACGGGAGCCGCATCGCAGGTATCCGGGTA CTGGATGGACCTCTCACAGACAGCATGGAGGCAGTGGCGTTCAACAAGCACTATCAGATC AATGACATCTACAGCTGCAGCTGGGGACCAGATGACGATGGGAAGACAGTGGATGGCCCC CATCAGCTTGGAAAGGCTGCCTTACAACATGGGGTGATTGCTGGTCGCCAGGGCTTTGGG AGCATCTTTGTGGTAGCCAGTGGCAACGGAGGCCAACACAACGACAACTGCAACTACGAT GGCTACGCCAACTCCATCTACACCGTCACCATAGGAGCTGTGGATGAGGAGGGACGCATG CCTTTCTATGCAGAAGAATGTGCCTCCATGCTGGCAGTCACCTTCAGTGGTGGGGACAAG ATGCTTCGGAGCATTGTGACCACTGACTGGGACCTTCAGAAGGGCACTGGCTGCACTGAG GGCCACACAGGGACCTCAGCTGCAGCGCCTCTGGCAGCTGGCATGATAGCCTTAATGCTG CAGGTGCGGCCCTGCCTCACGTGGCGTGACGTCCAGCACATCATTGTCTTCACAGCCACC CGGTATGAGGATCGCCGTGCAGAGTGGGTCACCAACGAGGCAGGCTTCAGCCATAGCCAC CAGCACGGTTTCGGCCTCCTCAACGCCTGGAGGCTCGTGAATGCAGCCAAGATCTGGACA TCTGTCCCTTACTTAGCATCCTACGTCAGTCCCGTGTTAAAAGAAAACAAGGCGATTCCG CAGTCCCCCCGTTCCCTGGAGGTCCTGTGGAATGTCAGCAGGATGGACCTGGAGATGTCA GGGCTGAAGACCCTGGAGCATGTGGCAGTGACAGTCTCCATCACTCACCCACGGCGCGGC AGCTTGGAGCTGAAGCTGTTCTGCCCCAGTGGCATGATGTCCCTCATCGGCGCCCCCCGC AGCATGGACTCGGATCCCAACGGCTTCAATGACTGGACCTTCTCCACTGTGCGATGCTGG GGGGAGAGAGCCCGAGGGACCTACAGGCTTGTCATCAGGGATGTCGGGGATGAGTCATTC CAGGTCGGCATCCTCCGGCAATGGCAGCTGACCCTATATGGCTCTGTGTGGAGTGCAGTA GACATCAGGGACAGACAAAGGCTGTTAGAGAGTGCCATGAGTGGAAAATACCTGCACGAT GACTTCGCCCTGCCCTGCCCACCGGGGCTGAAAATTCCTGAGGAAGATGGTTACACCATC ACCCCCAACACCCTCAAGACCCTGGTGCTGGTAGGCTGTTTCACCGTCTTCTGGACTGTT TACTACATGCTGGAAGTATATTTGAGCCAGAGGAATGTGGCTTCCAATCAAGTTTGTAGG AGTGGACCCTGCCACTGGCCCCATCGGAGCCGGAAAGCCAAGGAGGAAGGGACAGAGCTA GAATCAGTGCCACTTTGCAGCAGCAAGGATCCAGACGAAGTGGAAACAGAGAGCAGGGGC CCTCCCACCACCTCTGACCTCCTTGCCCCAGACCTGCTGGAGCAAGGGGACTGGAGCCTG TCCCAGAACAAGAGCGCCCTGGACTGCCCTCATCAGCACCTAGACGTACCGCACGGGAAG GAGGAGCAGATCTGCTGA |
GenBank Gene ID | Not Available |
GeneCard ID | Not Available |
GenAtlas ID | Not Available |
HGNC ID | HGNC:8748 |
Chromosome Location | 11 |
Locus | Not Available |
References |
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