Kinesin light chain 1

NameKinesin light chain 1
Synonyms
  • KLC
  • KLC 1
  • KNS2
Gene NameKLC1
OrganismHuman
Amino acid sequence
>lcl|BSEQ0009171|Kinesin light chain 1
MYDNMSTMVYIKEDKLEKLTQDEIISKTKQVIQGLEALKNEHNSILQSLLETLKCLKKDD
ESNLVEEKSNMIRKSLEMLELGLSEAQVMMALSNHLNAVESEKQKLRAQVRRLCQENQWL
RDELANTQQKLQKSEQSVAQLEEEKKHLEFMNQLKKYDDDISPSEDKDTDSTKEPLDDLF
PNDEDDPGQGIQQQHSSAAAAAQQGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQAL
EDLEKTSGHDHPDVATMLNILALVYRDQNKYKDAANLLNDALAIREKTLGKDHPAVAATL
NNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQGKYEEVEY
YYQRALEIYQTKLGPDDPNVAKTKNNLASCYLKQGKFKQAETLYKEILTRAHEREFGSVD
DENKPIWMHAEEREECKGKQKDGTSFGEYGGWYKACKVDSPTVTTTLKNLGALYRRQGKF
EAAETLEEAAMRSRKQGLDNVHKQRVAEVLNDPENMEKRRSRESLNVDVVKYESGPDGGE
EVSMSVEWNGGVSGRASFCGKRQQQQWPGRRHR
Number of residues573
Molecular Weight65309.09
Theoretical pINot Available
GO Classification
Functions
  • motor activity
  • microtubule motor activity
Processes
  • stress granule disassembly
  • axon cargo transport
  • microtubule-based movement
  • blood coagulation
  • small GTPase mediated signal transduction
  • antigen processing and presentation of exogenous peptide antigen via MHC class II
  • viral process
Components
  • ciliary rootlet
  • kinesin complex
  • membrane
  • microtubule
  • cytosol
  • cytoplasmic membrane-bounded vesicle
  • growth cone
  • axon
General FunctionMotor activity
Specific FunctionKinesin is a microtubule-associated force-producing protein that may play a role in organelle transport. The light chain may function in coupling of cargo to the heavy chain or in the modulation of its ATPase activity.
Pfam Domain Function
Transmembrane RegionsNot Available
GenBank Protein IDNot Available
UniProtKB IDQ07866
UniProtKB Entry NameKLC1_HUMAN
Cellular LocationCell projection
Gene sequence
>lcl|BSEQ0013650|Kinesin light chain 1 (KLC1)
ATGTATGACAACATGTCCACAATGGTGTACATAAAGGAAGACAAGTTGGAGAAGCTTACA
CAGGATGAAATTATTTCTAAGACAAAGCAAGTAATTCAGGGGCTGGAAGCTTTGAAGAAT
GAGCACAATTCCATTTTACAAAGTTTGCTGGAGACACTGAAGTGTTTGAAGAAAGATGAT
GAAAGTAATTTGGTGGAGGAGAAATCAAACATGATCCGGAAGTCACTGGAGATGTTGGAG
CTCGGCCTGAGTGAGGCACAGGTTATGATGGCTTTGTCAAATCACCTGAATGCTGTGGAG
TCCGAGAAGCAGAAACTGCGTGCGCAGGTTCGTCGTCTGTGCCAGGAGAATCAGTGGCTA
CGGGATGAACTGGCCAACACGCAGCAGAAACTGCAGAAGAGTGAGCAGTCTGTGGCTCAA
CTGGAGGAGGAGAAGAAGCATCTGGAGTTTATGAATCAGCTAAAAAAATATGATGACGAC
ATTTCCCCATCCGAGGACAAAGACACTGATTCTACCAAAGAGCCTCTGGATGACCTTTTC
CCCAATGATGAAGACGACCCAGGGCAAGGAATCCAGCAGCAGCACAGCAGTGCAGCCGCG
GCTGCCCAGCAGGGCGGCTACGAGATCCCCGCGCGGCTGCGGACGCTCCACAACCTGGTG
ATCCAGTACGCCTCGCAGGGGCGCTACGAGGTAGCTGTGCCCCTCTGCAAGCAGGCCCTG
GAGGACCTGGAGAAGACTTCAGGACACGACCACCCGGACGTGGCCACCATGCTCAACATC
CTGGCCTTGGTGTACAGGGATCAGAATAAATACAAAGATGCAGCTAACCTACTGAATGAT
GCCTTGGCTATTCGTGAGAAAACTTTGGGCAAAGATCATCCTGCGGTGGCGGCGACTTTG
AATAACCTTGCAGTCCTTTATGGTAAAAGAGGGAAGTACAAAGAAGCAGAGCCGTTGTGT
AAAAGAGCTCTGGAAATCCGAGAAAAGGTTTTGGGGAAGGATCACCCCGATGTTGCCAAG
CAGTTAAATAACTTGGCCTTACTGTGCCAGAACCAGGGCAAGTATGAAGAAGTAGAATAT
TATTATCAAAGAGCCCTCGAGATCTACCAGACAAAACTGGGACCTGATGACCCCAACGTG
GCTAAGACGAAAAATAACCTGGCATCCTGCTATTTGAAACAAGGAAAGTTCAAGCAAGCA
GAAACACTGTACAAAGAGATTCTCACTCGTGCACATGAAAGGGAGTTTGGTTCTGTAGAT
GATGAAAATAAACCCATCTGGATGCATGCTGAAGAAAGAGAAGAATGCAAAGGAAAGCAA
AAGGATGGGACATCTTTTGGAGAGTATGGCGGCTGGTACAAAGCCTGCAAAGTTGATAGT
CCAACTGTTACAACCACTCTAAAAAACCTTGGGGCACTTTACAGACGTCAAGGCAAATTT
GAAGCTGCAGAAACGTTAGAAGAAGCTGCTATGAGGTCTCGTAAACAGGGTCTTGACAAT
GTTCACAAACAGAGGGTGGCAGAAGTGCTCAATGACCCTGAGAACATGGAGAAGCGCAGG
AGCCGTGAGAGCCTCAACGTGGACGTGGTCAAGTACGAGAGTGGCCCTGACGGAGGGGAG
GAAGTGAGTATGAGCGTAGAGTGGAACGGGGATGGCACTGGATCTTTAAAACGCAGTGGT
TCCTTTAGCAAACTCCGGGCTTCCATTAGACGCAGCAGTGAGAAGCTGGTTAGGAAGCTG
AAGGGAGGAAGTTCACGAGAGAGTGAGCCAAAGAACCCCGGGGCGTCTCTGGCCGAGCCT
CTTTTTGTGGAAAACGACAGCAGCAGCAGTGGCCTGGAAGACGCCACCGCTAACTGA
GenBank Gene IDNot Available
GeneCard IDNot Available
GenAtlas IDNot Available
HGNC IDHGNC:6387
Chromosome Location14
LocusNot Available
References
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