Potassium voltage-gated channel subfamily C member 4
Name | Potassium voltage-gated channel subfamily C member 4 |
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Synonyms |
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Gene Name | KCNC4 |
Organism | Human |
Amino acid sequence | >lcl|BSEQ0006475|Potassium voltage-gated channel subfamily C member 4 MISSVCVSSYRGRKSGNKPPSKTCLKEEMAKGEASEKIIINVGGTRHETYRSTLRTLPGT RLAWLADPDGGGRPETDGGGVGSSGSSGGGGCEFFFDRHPGVFAYVLNYYRTGKLHCPAD VCGPLFEEELTFWGIDETDVEPCCWMTYRQHRDAEEALDIFESPDGGGSGAGPSDEAGDD ERELALQRLGPHEGGAGHGAGSGGCRGWQPRMWALFEDPYSSRAARVVAFASLFFILVSI TTFCLETHEAFNIDRNVTEILRVGNITSVHFRREVETEPILTYIEGVCVLWFTLEFLVRI VCCPDTLDFVKNLLNIIDFVAILPFYLEVGLSGLSSKAARDVLGFLRVVRFVRILRIFKL TRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGARPSDPRGNDHTDF KNIPIGFWWAVVTMTTLGYGDMYPKTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYS LAMAKQKLPKKRKKHVPRPAQLESPMYCKSEETSPRDSTCSDTSPPAREEGMIERKRADS KQNGDANAVLSDEEGAGLTQPLASSPTPEERRALRRSTTRDRNKKAAACFLLSTGDYACA DGSVRKGTFVLRDLPLQHSPEAACPPTAGTLFLPH |
Number of residues | 635 |
Molecular Weight | 69766.06 |
Theoretical pI | 6.98 |
GO Classification | Functions
Processes
Components
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General Function | Voltage-gated potassium channel activity |
Specific Function | This protein mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient. |
Pfam Domain Function | |
Transmembrane Regions | 227-247 278-298 313-333 345-364 381-401 452-472 |
GenBank Protein ID | Not Available |
UniProtKB ID | Q03721 |
UniProtKB Entry Name | KCNC4_HUMAN |
Cellular Location | Membrane |
Gene sequence | >lcl|BSEQ0012322|Potassium voltage-gated channel subfamily C member 4 (KCNC4) ATGATCAGCTCGGTGTGTGTCTCCTCCTACCGCGGGCGCAAGTCGGGGAACAAGCCTCCG TCCAAAACATGTCTGAAGGAGGAGATGGCCAAGGGCGAGGCGTCGGAGAAGATCATCATC AACGTGGGCGGCACGCGACATGAGACCTACCGCAGCACCCTGCGCACCCTACCGGGAACC CGCCTCGCCTGGCTGGCCGACCCCGACGGCGGGGGCCGGCCCGAGACCGATGGCGGCGGT GTGGGTAGCAGCGGCAGCAGCGGCGGCGGGGGCTGCGAGTTCTTCTTCGACAGGCACCCG GGCGTCTTCGCCTACGTGCTCAACTACTACCGCACCGGCAAGCTGCACTGCCCCGCGGAC GTGTGCGGGCCGCTCTTCGAAGAGGAGCTCACCTTCTGGGGCATCGACGAGACCGACGTG GAACCCTGCTGCTGGATGACCTACCGGCAGCACCGCGACGCCGAGGAGGCGCTCGACATC TTCGAGAGCCCGGACGGAGGCGGCAGCGGCGCGGGGCCCAGCGACGAGGCCGGCGACGAT GAGCGGGAGCTGGCCCTGCAGCGACTGGGCCCCCACGAGGGAGGCGCGGGCCATGGCGCC GGGTCTGGGGGCTGCCGCGGCTGGCAGCCCCGCATGTGGGCGCTCTTCGAGGATCCCTAC TCCTCCCGGGCCGCTAGGGTAGTGGCCTTTGCCTCTCTCTTCTTCATCCTGGTCTCCATC ACCACTTTCTGCCTGGAGACCCATGAGGCCTTTAATATCGACCGCAACGTGACAGAGATC CTCCGCGTAGGGAACATCACCAGCGTGCACTTCCGGCGGGAGGTAGAGACAGAGCCCATC CTGACCTACATCGAGGGCGTATGTGTGCTGTGGTTCACACTGGAGTTCCTGGTGCGCATC GTGTGCTGCCCCGACACGCTGGACTTCGTCAAGAACCTGCTCAACATCATCGACTTTGTG GCCATCCTGCCCTTCTACCTGGAGGTGGGGCTGAGCGGCCTGTCATCCAAGGCGGCCCGC GACGTGCTGGGCTTCCTGCGCGTGGTGCGCTTCGTGCGCATCCTGCGTATCTTCAAGCTC ACACGCCACTTCGTGGGGCTACGCGTGCTGGGCCACACCCTGAGGGCCAGCACCAATGAG TTCCTGCTGCTTATCATCTTCCTGGCCCTGGGTGTGCTCATCTTTGCCACCATGATCTAC TACGCTGAGCGCATTGGGGCCAGGCCCTCCGACCCTCGGGGTAATGACCACACCGACTTC AAGAACATCCCCATTGGCTTCTGGTGGGCTGTGGTCACCATGACGACACTGGGCTACGGA GACATGTACCCCAAGACGTGGTCAGGCATGCTGGTAGGGGCACTGTGTGCACTGGCTGGC GTGCTCACCATCGCCATGCCGGTGCCTGTCATCGTCAACAACTTCGGCATGTACTACTCC CTGGCCATGGCCAAGCAGAAGCTGCCCAAGAAACGGAAGAAGCACGTGCCACGGCCGGCG CAGCTGGAGTCACCCATGTACTGCAAGTCTGAGGAGACTTCCCCCCGGGACAGCACCTGC AGTGATACCAGCCCCCCTGCCCGGGAAGAGGGTATGATCGAGAGGAAACGGGCAGACTCT AAGCAGAATGGCGATGCCAACGCAGTGCTGTCTGATGAGGAGGGAGCTGGCCTCACCCAA CCCCTGGCCTCCTCCCCGACCCCCGAGGAGCGCCGGGCCCTGCGACGCTCCACCACTCGA GACAGAAACAAGAAGGCAGCTGCCTGCTTCCTGCTCAGCACTGGGGACTATGCCTGCGCC GATGGTAGTGTCCGGAAAGAGACCTGCCAAGACGCCCTCTCGTCCAACTATGCCCAGGCT GAAGTCCTCACCCTCTCTTAA |
GenBank Gene ID | AL137790 |
GeneCard ID | Not Available |
GenAtlas ID | KCNC4 |
HGNC ID | HGNC:6236 |
Chromosome Location | 1 |
Locus | 1p21 |
References |
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