NameRetinol-binding protein 5
Synonyms
  • Cellular retinol-binding protein III
  • CRBP-III
  • HRBPiso
Gene NameRBP5
OrganismHuman
Amino acid sequence
>lcl|BSEQ0010475|Retinol-binding protein 5
MPPNLTGYYRFVSQKNMEDYLQALNISLAVRKIALLLKPDKEIEHQGNHMTVRTLSTFRN
YTVQFDVGVEFEEDLRSVDGRKCQTIVTWEEEHLVCVQKGEVPNRGWRHWLEGEMLYLEL
TARDAVCEQVFRKVR
Number of residues135
Molecular Weight15931.17
Theoretical pI6.51
GO Classification
Functions
  • transporter activity
  • retinoid binding
  • retinal binding
  • retinol binding
Components
  • cytoplasm
  • extracellular exosome
General FunctionTransporter activity
Specific FunctionIntracellular transport of retinol.
Pfam Domain Function
Transmembrane RegionsNot Available
GenBank Protein ID13447447
UniProtKB IDP82980
UniProtKB Entry NameRET5_HUMAN
Cellular LocationCytoplasm
Gene sequence
>lcl|BSEQ0010476|Retinol-binding protein 5 (RBP5)
ATGCCTCCCAACCTCACTGGCTACTACCGCTTTGTCTCGCAGAAGAACATGGAGGACTAC
CTGCAAGCCCTAAACATCAGCTTGGCTGTGCGGAAGATCGCGCTGCTGCTGAAGCCGGAC
AAGGAGATCGAACACCAGGGCAACCACATGACGGTGAGGACGCTCAGCACCTTCCGAAAC
TACACTGTGCAGTTTGATGTGGGAGTGGAGTTTGAGGAGGACCTCAGGAGCGTGGACGGA
CGAAAATGCCAGACCATAGTAACCTGGGAGGAGGAGCACCTGGTGTGTGTGCAGAAAGGG
GAGGTCCCCAACCGGGGCTGGAGACACTGGCTGGAGGGAGAGATGCTGTATCTGGAACTG
ACTGCAAGGGATGCAGTGTGCGAGCAGGTCTTCAGGAAGGTCAGATAG
GenBank Gene IDAY007436
GeneCard IDNot Available
GenAtlas IDRBP5
HGNC IDHGNC:15847
Chromosome Location12
Locus12p13.31
References
  1. Folli C, Calderone V, Ottonello S, Bolchi A, Zanotti G, Stoppini M, Berni R: Identification, retinoid binding, and x-ray analysis of a human retinol-binding protein. Proc Natl Acad Sci U S A. 2001 Mar 27;98(7):3710-5. 11274389
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  4. Ho JC, Cheung ST, Poon WS, Lee YT, Ng IO, Fan ST: Down-regulation of retinol binding protein 5 is associated with aggressive tumor features in hepatocellular carcinoma. J Cancer Res Clin Oncol. 2007 Dec;133(12):929-36. Epub 2007 May 12. 17497168
  5. Bian Y, Song C, Cheng K, Dong M, Wang F, Huang J, Sun D, Wang L, Ye M, Zou H: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome. J Proteomics. 2014 Jan 16;96:253-62. doi: 10.1016/j.jprot.2013.11.014. Epub 2013 Nov 22. 24275569