Alpha-mannosidase 2x
Name | Alpha-mannosidase 2x |
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Synonyms |
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Gene Name | MAN2A2 |
Organism | Human |
Amino acid sequence | >lcl|BSEQ0009085|Alpha-mannosidase 2x MKLKKQVTVCGAAIFCVAVFSLYLMLDRVQHDPTRHQNGGNFPRSQISVLQNRIEQLEQL LEENHEIISHIKDSVLELTANAEGPPAMLPYYTVNGSWVVPPEPRPSFFSISPQDCQFAL GGRGQKPELQMLTVSEELPFDNVDGGVWRQGFDISYDPHDWDAEDLQVFVVPHSHNDPGW IKTFDKYYTEQTQHILNSMVSKLQEDPRRRFLWAEVSFFAKWWDNINVQKRAAVRRLVGN GQLEIATGGWVMPDEANSHYFALIDQLIEGHQWLERNLGATPRSGWAVDPFGYSSTMPYL LRRANLTSMLIQRVHYAIKKHFAATHSLEFMWRQTWDSDSSTDIFCHMMPFYSYDVPHTC GPDPKICCQFDFKRLPGGRINCPWKVPPRAITEANVAERAALLLDQYRKKSQLFRSNVLL VPLGDDFRYDKPQEWDAQFFNYQRLFDFFNSRPNLHVQAQFGTLSDYFDALYKRTGVEPG ARPPGFPVLSGDFFSYADREDHYWTGYYTSRPFYKSLDRVLEAHLRGAEVLYSLAAAHAR RSGLAGRYPLSDFTLLTEARRTLGLFQHHDAITGTAKEAVVVDYGVRLLRSLVNLKQVII HAAHYLVLGDKETYHFDPEAPFLQVDDTRLSHDALPERTVIQLDSSPRFVVLFNPLEQER FSMVSLLVNSPRVRVLSEEGQPLAVQISAHWSSATEAVPDVYQVSVPVRLPALGLGVLQL QLGLDGHRTLPSSVRIYLHGRQLSVSRHEAFPLRVIDSGTSDFALSNRYMQVWFSGLTGL LKSIRRVDEEHEQQVDMQVLVYGTRTSKDKSGAYLFLPDGEAKPYVPKEPPVLRVTEGPF FSEVVAYYEHIHQAVRLYNLPGVEGLSLDISSLVDIRDYVNKELALHIHTDIDSQGIFFT DLNGFQVQPRRYLKKLPLQANFYPMPVMAYIQDAQKRLTLHTAQALGVSSLKDGQLEVIL DRRLMQDDNRGLGQGLKDNKRTCNRFRLLLERRTVGSEVQDSHSTSYPSLLSHLTSMYLN APALALPVARMQLPGPGLRSFHPLASSLPCDFHLLNLRTLQAEEDTLPSAETALILHRKG FDCGLEAKNLGFNCTTSQGKVALGSLFHGLDVVFLQPTSLTLLYPLASPSNSTDVYLEPM EIATFRLRLG |
Number of residues | 1150 |
Molecular Weight | 130537.495 |
Theoretical pI | Not Available |
GO Classification | Functions
Processes
Components
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General Function | Zinc ion binding |
Specific Function | Catalyzes the first committed step in the biosynthesis of complex N-glycans. It controls conversion of high mannose to complex N-glycans; the final hydrolytic step in the N-glycan maturation pathway. |
Pfam Domain Function | |
Transmembrane Regions | 6-26 |
GenBank Protein ID | Not Available |
UniProtKB ID | P49641 |
UniProtKB Entry Name | MA2A2_HUMAN |
Cellular Location | Golgi apparatus membrane |
Gene sequence | >lcl|BSEQ0013604|Alpha-mannosidase 2x (MAN2A2) ATGAAGCTGAAAAAGCAGGTGACAGTGTGTGGGGCTGCCATCTTCTGTGTGGCAGTCTTC TCGCTCTACCTCATGCTGGACCGAGTGCAACACGATCCCACCCGACACCAGAATGGTGGG AACTTCCCCCGGAGCCAAATTTCTGTGCTGCAGAACCGCATTGAGCAGCTGGAGCAGCTT TTGGAGGAGAACCATGAGATTATCAGCCATATCAAGGACTCCGTGCTGGAGCTGACAGCC AACGCAGAGGGCCCGCCCGCCATGCTGCCCTACTACACGGTCAATGGCTCCTGGGTGGTG CCACCGGAGCCCCGGCCCAGCTTCTTCTCCATCTCCCCGCAGGACTGCCAGTTTGCTTTG GGGGGCCGGGGTCAGAAGCCAGAGCTGCAGATGCTCACTGTGTCGGAGGAGCTGCCGTTT GACAACGTGGATGGTGGTGTGTGGAGGCAAGGCTTCGACATCTCCTACGACCCGCACGAC TGGGATGCTGAAGACCTGCAGGTGTTTGTGGTGCCCCACTCTCACAATGACCCAGGCTGG ATCAAGACCTTTGACAAGTACTACACAGAGCAGACCCAACACATCCTCAATAGCATGGTG TCTAAGCTGCAGGAGGACCCCCGGCGGCGCTTCCTCTGGGCAGAGGTCTCCTTCTTCGCC AAGTGGTGGGACAACATCAATGTCCAAAAGAGAGCGGCAGTCCGAAGGCTGGTGGGAAAC GGGCAGCTGGAGATTGCGACAGGAGGCTGGGTGATGCCAGATGAGGCCAATTCCCACTAC TTTGCATTGATTGACCAGCTCATCGAAGGACACCAGTGGCTGGAGAGAAATCTTGGTGCA ACCCCCCGCTCTGGCTGGGCAGTGGACCCCTTTGGATACAGCTCCACCATGCCTTACCTG CTGCGCCGTGCCAACCTCACCAGCATGCTGATTCAGAGAGTGCACTATGCCATCAAGAAG CACTTTGCTGCCACCCACAGCCTAGAGTTCATGTGGAGGCAGACATGGGACTCGGACTCC AGCACAGACATCTTCTGTCACATGATGCCCTTCTACAGCTATGACGTCCCCCATACCTGT GGCCCAGATCCCAAGATCTGCTGCCAATTTGATTTCAAACGCCTGCCTGGTGGGCGCATC AACTGCCCTTGGAAGGTGCCACCCCGGGCCATCACAGAGGCCAACGTGGCAGAGAGGGCA GCCCTGCTTCTGGACCAATACCGGAAGAAGTCCCAGCTGTTCCGAAGCAACGTCCTCCTG GTGCCTCTTGGAGATGACTTCCGATATGACAAGCCCCAGGAGTGGGATGCCCAGTTCTTC AACTACCAACGGCTCTTTGACTTCTTCAACAGCAGGCCTAACCTCCATGTGCAGGCCCAG TTTGGCACTCTTTCTGACTATTTTGATGCCCTGTACAAGAGGACAGGGGTGGAGCCAGGG GCCCGGCCTCCAGGGTTTCCTGTGCTGAGCGGGGATTTCTTCTCCTATGCGGACCGGGAG GATCATTACTGGACAGGCTATTACACTTCCCGGCCCTTCTACAAGAGCTTAGACCGAGTC CTGGAAGCCCACCTGCGGGGGGCAGAGGTTCTGTACAGCCTGGCTGCAGCTCACGCTCGC CGCTCTGGTCTGGCTGGCCGGTACCCACTGTCTGATTTCACCCTCCTGACGGAAGCTCGG CGCACATTGGGGCTCTTCCAGCATCACGATGCCATCACTGGCACGGCCAAGGAGGCTGTG GTGGTGGACTATGGGGTCAGGCTTCTGCGCTCCCTTGTCAACCTGAAGCAGGTCATCATT CATGCAGCCCACTATCTGGTGCTGGGGGACAAGGAGACCTACCACTTTGACCCTGAGGCG CCCTTCCTCCAAGTGGATGACACTCGCTTAAGTCACGACGCCCTCCCAGAGCGCACGGTG ATCCAGCTGGATTCCTCGCCCAGGTTTGTGGTCCTATTCAACCCACTGGAACAGGAGCGA TTCAGCATGGTGTCCCTGCTGGTCAACTCTCCCCGCGTGCGTGTCCTTTCGGAGGAGGGT CAGCCCCTGGCCGTGCAGATCAGCGCACACTGGAGCTCTGCCACCGAGGCGGTCCCTGAC GTCTACCAGGTGTCTGTGCCTGTCCGCCTGCCAGCCCTGGGCCTGGGCGTGCTGCAGCTA CAGCTGGGCCTGGATGGGCACCGCACGCTGCCCTCCTCTGTGCGCATCTACCTGCACGGC CGGCAGCTGTCCGTCAGCAGGCACGAAGCGTTTCCTCTCCGTGTCATTGACTCTGGCACC AGCGACTTCGCCCTCAGCAACCGCTACATGCAGGTCTGGTTCTCAGGCCTTACTGGGCTC CTCAAGAGCATCCGAAGGGTGGATGAGGAGCACGAGCAGCAGGTGGACATGCAGGTCCTT GTCTATGGCACCCGTACGTCCAAAGACAAGAGTGGAGCCTACCTCTTCCTGCCCGATGGC GAGGCCAAGCCCTACGTCCCCAAGGAGCCCCCCGTGCTGCGTGTCACTGAAGGCCCTTTC TTCTCAGAGGTGGTTGCGTACTATGAGCACATTCACCAGGCGGTCCGGCTTTACAATCTG CCAGGGGTGGAGGGGCTGTCTCTGGACATATCATCCCTGGTGGACATCCGGGACTACGTC AACAAGGAGCTGGCCCTGCACATCCATACAGACATCGACAGCCAGGGTATCTTCTTCACA GACCTCAATGGCTTTCAGGTGCAGCCCCGACGGTATCTGAAGAAGCTCCCCCTCCAGGCC AACTTCTACCCCATGCCAGTCATGGCCTATATCCAGGACGCACAGAAGCGCCTCACGCTG CACACTGCCCAGGCCCTGGGTGTCTCTAGCCTCAAAGATGGCCAGCTGGAGGTGATCTTG GACCGGCGGCTGATGCAGGATGACAACCGGGGCCTAGGCCAAGGGCTCAAGGACAACAAG AGAACCTGCAACCGTTTCCGCCTCCTGCTAGAGCGGCGAACCGTGGGCAGTGAGGTCCAA GATAGCCACTCTACCAGCTACCCATCCCTCCTCAGCCACCTGACCTCCATGTACCTGAAC GCCCCGGCGCTCGCTCTGCCTGTAGCCAGGATGCAGCTCCCAGGCCCTGGTCTGCGCTCA TTTCATCCTCTGGCTTCCTCACTGCCCTGTGACTTCCACCTGCTCAACCTACGTACGCTC CAGGCTGAGGAGGACACCCTACCCTCGGCGGAGACCGCACTCATCTTACACCGCAAGGGT TTTGACTGCGGCCTGGAGGCCAAGAACTTGGGCTTCAACTGCACCACAAGCCAAGGCAAG GTAGCCCTGGGCAGCCTTTTCCATGGCCTGGATGTGGTATTCCTTCAGCCAACCTCCTTG ACGTTACTGTACCCTCTGGCCTCCCCGTCCAACAGCACTGACGTCTATTTGGAGCCCATG GAGATTGCTACCTTTCGCCTCCGCTTGGGTTAG |
GenBank Gene ID | Not Available |
GeneCard ID | Not Available |
GenAtlas ID | Not Available |
HGNC ID | HGNC:6825 |
Chromosome Location | 15 |
Locus | Not Available |
References |
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