Folate receptor gamma
Name | Folate receptor gamma |
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Synonyms |
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Gene Name | FOLR3 |
Organism | Human |
Amino acid sequence | >lcl|BSEQ0001300|Folate receptor gamma MAWQMMQLLLLALVTAAGSAQPRSARARTDLLNVCMNAKHHKTQPSPEDELYGQCSPWKK NACCTASTSQELHKDTSRLYNFNWDHCGKMEPTCKRHFIQDSCLYECSPNLGPWIRQVNQ SWRKERILNVPLCKEDCERWWEDCRTSYTCKSNWHKGWNWTSGINECPAGALCSTFESYF PTPAALCEGLWSHSFKVSNYSRGSGRCIQMWFDSAQGNPNEEVAKFYAAAMNAGAPSRGI IDS |
Number of residues | 243 |
Molecular Weight | 27638.0 |
Theoretical pI | 7.88 |
GO Classification | Functions
Processes
Components
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General Function | Folic acid binding |
Specific Function | Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate to the interior of cells. Isoform Short does not bind folate. |
Pfam Domain Function |
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Transmembrane Regions | Not Available |
GenBank Protein ID | 473236 |
UniProtKB ID | P41439 |
UniProtKB Entry Name | FOLR3_HUMAN |
Cellular Location | Secreted |
Gene sequence | >lcl|BSEQ0020471|Folate receptor gamma (FOLR3) ATGGACATGGCCTGGCAGATGATGCAGCTGCTGCTTCTGGCTTTGGTGACTGCTGCGGGG AGTGCCCAGCCCAGGAGTGCGCGGGCCAGGACGGACCTGCTCAATGTCTGCATGAACGCC AAGCACCACAAGACACAGCCCAGCCCCGAGGACGAGCTGTATGGCCAGTGCAGTCCCTGG AAGAAGAATGCCTGCTGCACGGCCAGCACCAGCCAGGAGCTGCACAAGGACACCTCCCGC CTGTACAACTTTAACTGGGATCACTGTGGTAAGATGGAACCCACCTGCAAGCGCCACTTT ATCCAGGACAGCTGTCTCTATGAGTGCTCACCCAACCTGGGGCCCTGGATCCGGCAGGTC AACCAGAGCTGGCGCAAAGAGCGCATTCTGAACGTGCCCCTGTGCAAAGAGGACTGTGAG CGCTGGTGGGAGGACTGTCGCACCTCCTACACCTGCAAAAGCAACTGGCACAAAGGCTGG AATTGGACCTCAGGGATTAATGAGTGTCCGGCCGGGGCCCTCTGCAGCACCTTTGAGTCC TACTTCCCCACTCCAGCCGCCCTTTGTGAAGGCCTCTGGAGCCACTCCTTCAAGGTCAGC AACTATAGTCGAGGGAGCGGCCGCTGCATCCAGATGTGGTTTGACTCAGCCCAGGGCAAC CCCAATGAGGAGGTGGCCAAGTTCTATGCTGCGGCCATGAATGCTGGGGCCCCGTCTCGT GGGATTATTGATTCCTGA |
GenBank Gene ID | Z32564 |
GeneCard ID | Not Available |
GenAtlas ID | FOLR3 |
HGNC ID | HGNC:3795 |
Chromosome Location | 11 |
Locus | 11q13 |
References |
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