NameHistone H2B type 1-B
Synonyms
  • H2B/f
  • H2BFF
  • Histone H2B.1
  • Histone H2B.f
Gene NameHIST1H2BB
OrganismHuman
Amino acid sequence
>lcl|BSEQ0020836|Histone H2B type 1-B
MPEPSKSAPAPKKGSKKAITKAQKKDGKKRKRSRKESYSIYVYKVLKQVHPDTGISSKAM
GIMNSFVNDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVT
KYTSSK
Number of residues126
Molecular Weight13950.075
Theoretical pINot Available
GO Classification
Functions
  • DNA binding
Processes
  • chromatin organization
  • nucleosome assembly
Components
  • nucleus
  • nucleoplasm
  • nuclear chromosome, telomeric region
  • nucleosome
  • cytoplasm
General FunctionDna binding
Specific FunctionCore component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Pfam Domain Function
Transmembrane RegionsNot Available
GenBank Protein IDNot Available
UniProtKB IDP33778
UniProtKB Entry NameH2B1B_HUMAN
Cellular LocationNucleus
Gene sequence
>lcl|BSEQ0020837|Histone H2B type 1-B (HIST1H2BB)
ATGCCTGAACCCTCTAAGTCTGCTCCAGCCCCTAAAAAGGGTTCTAAGAAGGCTATCACT
AAGGCGCAGAAGAAGGATGGTAAGAAGCGTAAGCGCAGCCGCAAGGAGAGCTATTCTATC
TATGTGTACAAGGTTCTGAAGCAGGTCCACCCCGACACCGGCATCTCATCCAAGGCCATG
GGGATCATGAATTCCTTCGTCAACGACATCTTCGAGCGCATCGCGGGCGAGGCTTCTCGC
CTGGCTCACTACAATAAGCGCTCGACCATCACCTCCAGGGAGATTCAGACGGCTGTGCGC
CTGCTGCTGCCTGGGGAGCTGGCTAAGCATGCTGTGTCCGAGGGCACTAAGGCAGTTACC
AAGTACACTAGCTCTAAATAA
GenBank Gene IDNot Available
GeneCard IDNot Available
GenAtlas IDNot Available
HGNC IDHGNC:4751
Chromosome Location6
LocusNot Available
References
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