Glutathione S-transferase theta-1
Name | Glutathione S-transferase theta-1 |
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Synonyms |
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Gene Name | GSTT1 |
Organism | Human |
Amino acid sequence | >lcl|BSEQ0037084|Glutathione S-transferase theta-1 MGLELYLDLLSQPCRAVYIFAKKNDIPFELRIVDLIKGQHLSDAFAQVNPLKKVPALKDG DFTLTESVAILLYLTRKYKVPDYWYPQDLQARARVDEYLAWQHTTLRRSCLRALWHKVMF PVFLGEPVSPQTLAATLAELDVTLQLLEDKFLQNKAFLTGPHISLADLVAITELMHPVGA GCQVFEGRPKLATWRQRVEAAVGEDLFQEAHEVILKAKDFPPADPTIKQKLMPWVLAMIR |
Number of residues | 240 |
Molecular Weight | 27334.755 |
Theoretical pI | 7.6 |
GO Classification | Functions
Processes
Components
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General Function | Glutathione transferase activity |
Specific Function | Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Acts on 1,2-epoxy-3-(4-nitrophenoxy)propane, phenethylisothiocyanate 4-nitrobenzyl chloride and 4-nitrophenethyl bromide. Displays glutathione peroxidase activity with cumene hydroperoxide. |
Pfam Domain Function | |
Transmembrane Regions | Not Available |
GenBank Protein ID | 510905 |
UniProtKB ID | P30711 |
UniProtKB Entry Name | GSTT1_HUMAN |
Cellular Location | Cytoplasm |
Gene sequence | >lcl|BSEQ0010578|Glutathione S-transferase theta-1 (GSTT1) ATGGGCCTGGAGCTGTACCTGGACCTGCTGTCCCAGCCCTGCCGCGCTGTTTACATCTTT GCCAAGAAGAACGACATTCCCTTCGAGCTGCGCATCGTGGATCTGATTAAAGGTCAGCAC TTAAGCGATGCCTTTGCCCAGGTGAACCCCCTCAAGAAGGTGCCAGCCTTGAAGGACGGG GACTTCACCTTGACGGAGAGTGTGGCCATCCTGCTCTACCTGACGCGCAAATATAAGGTC CCTGACTACTGGTACCCTCAGGACCTGCAGGCCCGTGCCCGTGTGGATGAGTACCTGGCA TGGCAGCACACGACTCTGCGGAGAAGCTGCCTCCGGGCCTTGTGGCATAAGGTGATGTTC CCTGTTTTCCTGGGTGAGCCAGTATCTCCCCAGACACTGGCAGCCACCCTGGCAGAGTTG GATGTGACCCTGCAGTTGCTCGAGGACAAGTTCCTCCAGAACAAGGCCTTCCTTACTGGT CCTCACATCTCCTTAGCTGACCTCGTAGCCATCACGGAGCTGATGCATCCCGTGGGTGCT GGCTGCCAAGTCTTCGAAGGCCGACCCAAGCTGGCCACATGGCGGCAGCGCGTGGAGGCA GCAGTGGGGGAGGACCTCTTCCAGGAGGCCCATGAGGTCATTCTGAAGGCCAAGGACTTC CCACCTGCAGACCCCACCATAAAGCAGAAGCTGATGCCCTGGGTGCTGGCCATGATCCGG TGA |
GenBank Gene ID | X79389 |
GeneCard ID | Not Available |
GenAtlas ID | GSTT1 |
HGNC ID | HGNC:4641 |
Chromosome Location | 22 |
Locus | 22q11.23 |
References |
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