ATP synthase subunit delta, mitochondrial
| Name | ATP synthase subunit delta, mitochondrial |
|---|---|
| Synonyms |
|
| Gene Name | ATP5D |
| Organism | Human |
| Amino acid sequence | >lcl|BSEQ0018957|ATP synthase subunit delta, mitochondrial MLPAALLRRPGLGRLVRHARAYAEAAAAPAAASGPNQMSFTFASPTQVFFNGANVRQVDV PTLTGAFGILAAHVPTLQVLRPGLVVVHAEDGTTSKYFVSSGSIAVNADSSVQLLAEEAV TLDMLDLGAAKANLEKAQAELVGTADEATRAEIQIRIEANEALVKALE |
| Number of residues | 168 |
| Molecular Weight | 17489.755 |
| Theoretical pI | 5.19 |
| GO Classification | Functions
Processes
Components
|
| General Function | Transporter activity |
| Specific Function | Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP turnover in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(1) domain and of the central stalk which is part of the complex rotary element. Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits. |
| Pfam Domain Function |
|
| Transmembrane Regions | Not Available |
| GenBank Protein ID | 12586 |
| UniProtKB ID | P30049 |
| UniProtKB Entry Name | ATPD_HUMAN |
| Cellular Location | Mitochondrion |
| Gene sequence | >lcl|BSEQ0018958|ATP synthase subunit delta, mitochondrial (ATP5D) ATGCTGCCCGCCGCGCTGCTCCGCCGCCCGGGACTTGGCCGCCTCGTCCGCCACGCCCGT GCCTATGCCGAGGCCGCCGCCGCCCCGGCTGCCGCCTCTGGCCCCAACCAGATGTCCTTC ACCTTCGCCTCTCCCACGCAGGTGTTCTTCAACGGTGCCAACGTCCGGCAGGTGGACGTG CCCACGCTGACCGGAGCCTTCGGCATCCTGGCGGCCCACGTGCCCACGCTGCAGGTCCTG CGGCCGGGGCTGGTCGTGGTGCATGCAGAGGACGGCACCACCTCCAAATACTTTGTGAGC AGCGGTTCCATCGCAGTGAACGCCGACTCTTCGGTGCAGTTGTTGGCCGAAGAGGCCGTG ACGCTGGACATGTTGGACCTGGGGGCAGCCAAGGCAAACTTGGAGAAGGCCCAGGCGGAG CTGGTGGGGACAGCTGACGAGGCCACGCGGGCAGAGATCCAGATCCGAATCGAGGCCAAC GAGGCCCTGGTGAAGGCCCTGGAGTAG |
| GenBank Gene ID | X63422 |
| GeneCard ID | Not Available |
| GenAtlas ID | ATP5D |
| HGNC ID | HGNC:837 |
| Chromosome Location | 19 |
| Locus | 19p13.3 |
| References |
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