NameProtein S100-A4
Synonyms
  • Calvasculin
  • CAPL
  • Metastasin
  • MTS1
  • Placental calcium-binding protein
  • Protein Mts1
  • S100 calcium-binding protein A4
Gene NameS100A4
OrganismHuman
Amino acid sequence
>lcl|BSEQ0013033|Protein S100-A4
MACPLEKALDVMVSTFHKYSGKEGDKFKLNKSELKELLTRELPSFLGKRTDEAAFQKLMS
NLDSNRDNEVDFQEYCVFLSCIAMMCNEFFEGFPDKQPRKK
Number of residues101
Molecular Weight11728.41
Theoretical pI5.92
GO Classification
Functions
  • calcium ion binding
  • poly(A) RNA binding
  • RAGE receptor binding
Processes
  • positive regulation of I-kappaB kinase/NF-kappaB signaling
  • epithelial to mesenchymal transition
Components
  • nucleus
  • extracellular space
  • extracellular exosome
  • perinuclear region of cytoplasm
  • neuron projection
General FunctionRage receptor binding
Specific FunctionNot Available
Pfam Domain Function
Transmembrane RegionsNot Available
GenBank Protein ID179917
UniProtKB IDP26447
UniProtKB Entry NameS10A4_HUMAN
Cellular LocationNot Available
Gene sequence
>lcl|BSEQ0013034|Protein S100-A4 (S100A4)
ATGGCGTGCCCTCTGGAGAAGGCCCTGGATGTGATGGTGTCCACCTTCCACAAGTACTCG
GGCAAAGAGGGTGACAAGTTCAAGCTCAACAAGTCAGAACTAAAGGAGCTGCTGACCCGG
GAGCTGCCCAGCTTCTTGGGGAAAAGGACAGATGAAGCTGCTTTCCAGAAGCTGATGAGC
AACTTGGACAGCAACAGGGACAACGAGGTGGACTTCCAAGAGTACTGTGTCTTCCTGTCC
TGCATCGCCATGATGTGTAACGAATTCTTTGAAGGCTTCCCAGATAAGCAGCCCAGGAAG
AAATGA
GenBank Gene IDM80563
GeneCard IDNot Available
GenAtlas IDNot Available
HGNC IDHGNC:10494
Chromosome Location1
Locus1q21
References
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  2. Engelkamp D, Schafer BW, Mattei MG, Erne P, Heizmann CW: Six S100 genes are clustered on human chromosome 1q21: identification of two genes coding for the two previously unreported calcium-binding proteins S100D and S100E. Proc Natl Acad Sci U S A. 1993 Jul 15;90(14):6547-51. 8341667
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