Neutrophil collagenase
Name | Neutrophil collagenase |
---|---|
Synonyms |
|
Gene Name | MMP8 |
Organism | Human |
Amino acid sequence | >lcl|BSEQ0010824|Neutrophil collagenase MFSLKTLPFLLLLHVQISKAFPVSSKEKNTKTVQDYLEKFYQLPSNQYQSTRKNGTNVIV EKLKEMQRFFGLNVTGKPNEETLDMMKKPRCGVPDSGGFMLTPGNPKWERTNLTYRIRNY TPQLSEAEVERAIKDAFELWSVASPLIFTRISQGEADINIAFYQRDHGDNSPFDGPNGIL AHAFQPGQGIGGDAHFDAEETWTNTSANYNLFLVAAHEFGHSLGLAHSSDPGALMYPNYA FRETSNYSLPQDDIDGIQAIYGLSSNPIQPTGPSTPKPCDPSLTFDAITTLRGEILFFKD RYFWRRHPQLQRVEMNFISLFWPSLPTGIQAAYEDFDRDLIFLFKGNQYWALSGYDILQG YPKDISNYGFPSSVQAIDAAVFYRSKTYFFVNDQFWRYDNQRQFMEPGYPKSISGAFPGI ESKVDAVFQQEHFFHVFSGPRYYAFDLIAQRVTRVARGNKWLNCRYG |
Number of residues | 467 |
Molecular Weight | 53411.72 |
Theoretical pI | 6.86 |
GO Classification | Functions
Processes
Components
|
General Function | Zinc ion binding |
Specific Function | Can degrade fibrillar type I, II, and III collagens. |
Pfam Domain Function | |
Transmembrane Regions | Not Available |
GenBank Protein ID | 180618 |
UniProtKB ID | P22894 |
UniProtKB Entry Name | MMP8_HUMAN |
Cellular Location | Cytoplasmic granule |
Gene sequence | >lcl|BSEQ0010825|Neutrophil collagenase (MMP8) ATGCAACAAATACCTCAAGAGAAGTCAATTAATGACTACCTGGAAAAGTTCTACCAATTA CCAAGCAACCAGTATCAGTCTACAAGGAAGAATGGCACTAATGTGATCGTTGAAAAGCTT AAAGAAATGCAGCGATTTTTTGGGTTGAATGTGACGGGGAAGCCAAATGAGGAAACTCTG GACATGATGAAAAAGCCTCGCTGTGGAGTGCCTGACAGTGGTGGTTTTATGTTAACCCCA GGAAACCCCAAGTGGGAACGCACTAACTTGACCTACAGGATTCGAAACTATACCCCACAG CTGTCAGAGGCTGAGGTAGAAAGAGCTATCAAGGATGCCTTTGAACTCTGGAGTGTTGCA TCACCTCTCATCTTCACCAGGATCTCACAGGGAGAGGCAGATATCAACATTGCTTTTTAC CAAAGAGATCACGGTGACAATTCTCCATTTGATGGACCCAATGGAATCCTTGCTCATGCC TTTCAGCCAGGCCAAGGTATTGGAGGAGATGCTCATTTTGATGCCGAAGAAACATGGACC AACACCTCCGCAAATTACAACTTGTTTCTTGTTGCTGCTCATGAATTTGGCCATTCTTTG GGGCTCGCTCACTCCTCTGACCCTGGTGCCTTGATGTATCCCAACTATGCTTTCAGGGAA ACCAGCAACTACTCACTCCCTCAAGATGACATCGATGGCATTCAGGCCATCTATGGACTT TCAAGCAACCCTATCCAACCTACTGGACCAAGCACACCCAAACCCTGTGACCCCAGTTTG ACATTTGATGCTATCACCACACTCCGTGGAGAAATACTTTTCTTTAAAGACAGGTACTTC TGGAGAAGGCATCCTCAGCTACAAAGAGTCGAAATGAATTTTATTTCTCTATTCTGGCCA TCCCTTCCAACTGGTATACAGGCTGCTTATGAAGATTTTGACAGAGACCTCATTTTCCTA TTTAAAGGCAACCAATACTGGGCTCTGAGTGGCTATGATATTCTGCAAGGTTATCCCAAG GATATATCAAACTATGGCTTCCCCAGCAGCGTCCAAGCAATTGACGCAGCTGTTTTCTAC AGAAGTAAAACATACTTCTTTGTAAATGACCAATTCTGGAGATATGATAACCAAAGACAA TTCATGGAGCCAGGTTATCCCAAAAGCATATCAGGTGCCTTTCCAGGAATAGAGAGTAAA GTTGATGCAGTTTTCCAGCAAGAACATTTCTTCCATGTCTTCAGTGGACCAAGATATTAC GCATTTGATCTTATTGCTCAGAGAGTTACCAGAGTTGCAAGAGGCAATAAATGGCTTAAC TGTAGATATGGCTGA |
GenBank Gene ID | J05556 |
GeneCard ID | Not Available |
GenAtlas ID | MMP8 |
HGNC ID | HGNC:7175 |
Chromosome Location | 11 |
Locus | 11q22.3 |
References |
|