NameHistone H2B type F-M
Synonyms
  • H2B/s
  • Histone H2B.s
Gene NameH2BFM
OrganismHuman
Amino acid sequence
>lcl|BSEQ0013518|Histone H2B type F-M
MAAASAMAEASSETTSEEGQSIQEPKEANSTKAQKQKRRGCRGSRRRHANRRGDSFGDSF
TPYFPRVLKQVHQGLSLSQEAVSVMDSMIHDILDRIATEAGQLAHYTKRVTITSRDIQMA
VRLLLPGKMGKLAEAQGTNAALRTSLCAIWQQRK
Number of residues154
Molecular Weight17001.165
Theoretical pINot Available
GO Classification
Functions
  • DNA binding
Processes
  • nucleosome assembly
Components
  • nuclear nucleosome
General FunctionDna binding
Specific FunctionCore component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Pfam Domain Function
Transmembrane RegionsNot Available
GenBank Protein IDNot Available
UniProtKB IDP0C1H6
UniProtKB Entry NameH2BFM_HUMAN
Cellular LocationNucleus
Gene sequence
>lcl|BSEQ0013519|Histone H2B type F-M (H2BFM)
ATGGCCGCTGCTTCCGCCATGGCTGAGGCTTCCTCTGAGACAACCTCGGAGGAAGGCCAG
AGCATCCAGGAGCCCAAAGAGGCCAACTCCACGAAGGCCCAGAAGCAGAAGAGGCGAGGG
TGCCGAGGCTCCCGCAGGCGCCACGCCAACCGCCGTGGGGACAGCTTCGGGGACAGCTTC
ACCCCCTATTTCCCCCGGGTGCTGAAGCAGGTTCACCAGGGCCTCAGCCTTTCCCAGGAG
GCCGTGAGTGTCATGGATTCTATGATCCATGACATATTGGACCGCATCGCCACCGAGGCT
GGTCAGCTGGCCCATTACACCAAGCGCGTGACCATCACCTCCCGGGACATCCAGATGGCC
GTGCGACTGCTGCTGCCGGGGAAGATGGGCAAGCTCGCCGAGGCCCAGGGCACGAATGCC
GCCCTCAGAACTTCATTATGTGCGATATGGCAACAGAGAAAGTGA
GenBank Gene IDNot Available
GeneCard IDNot Available
GenAtlas IDNot Available
HGNC IDHGNC:27867
Chromosome LocationX
LocusNot Available
References
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