NameRho-related GTP-binding protein RhoC
Synonyms
  • ARH9
  • ARHC
  • h9
  • Rho cDNA clone 9
Gene NameRHOC
OrganismHuman
Amino acid sequence
>lcl|BSEQ0013614|Rho-related GTP-binding protein RhoC
MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYIADIEVDGKQVELALWDT
AGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKD
LRQDEHTRRELAKMKQEPVRSEEGRDMANRISAFGYLECSAKTKEGVREVFEMATRAGLQ
VRKNKRRRGCPIL
Number of residues193
Molecular Weight22006.16
Theoretical pINot Available
GO Classification
Functions
  • signal transducer activity
  • GTP binding
Processes
  • small GTPase mediated signal transduction
  • cytokinesis
  • axon guidance
  • positive regulation of I-kappaB kinase/NF-kappaB signaling
  • wound healing, spreading of cells
  • regulation of small GTPase mediated signal transduction
  • apical junction assembly
  • positive regulation of lipase activity
  • skeletal muscle satellite cell migration
Components
  • plasma membrane
  • cytosol
  • extracellular exosome
  • cleavage furrow
  • nucleus
General FunctionSignal transducer activity
Specific FunctionRegulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers. Serves as a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis. Regulates apical junction formation in bronchial epithelial cells.
Pfam Domain Function
Transmembrane RegionsNot Available
GenBank Protein IDNot Available
UniProtKB IDP08134
UniProtKB Entry NameRHOC_HUMAN
Cellular LocationCell membrane
Gene sequence
>lcl|BSEQ0013615|Rho-related GTP-binding protein RhoC (RHOC)
ATGGCTGCAATCCGAAAGAAGCTGGTGATCGTTGGGGATGGTGCCTGTGGGAAGACCTGC
CTCCTCATCGTCTTCAGCAAGGATCAGTTTCCGGAGGTCTACGTCCCTACTGTCTTTGAG
AACTATATTGCGGACATTGAGGTGGACGGCAAGCAGGTGGAGCTGGCTCTGTGGGACACA
GCAGGGCAGGAAGACTATGATCGACTGCGGCCTCTCTCCTACCCGGACACTGATGTCATC
CTCATGTGCTTCTCCATCGACAGCCCTGACAGCCTGGAAAACATTCCTGAGAAGTGGACC
CCAGAGGTGAAGCACTTCTGCCCCAACGTGCCCATCATCCTGGTGGGGAATAAGAAGGAC
CTGAGGCAAGACGAGCACACCAGGAGAGAGCTGGCCAAGATGAAGCAGGAGCCCGTTCGG
TCTGAGGAAGGCCGGGACATGGCGAACCGGATCAGTGCCTTTGGCTACCTTGAGTGCTCA
GCCAAGACCAAGGAGGGAGTGCGGGAGGTGTTTGAGATGGCCACTCGGGCTGGCCTCCAG
GTCCGCAAGAACAAGCGTCGGAGGGGCTGTCCCATTCTCTGA
GenBank Gene IDNot Available
GeneCard IDNot Available
GenAtlas IDNot Available
HGNC IDHGNC:669
Chromosome Location1
LocusNot Available
References
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