Transthyretin

NameTransthyretin
Synonyms
  • ATTR
  • PALB
  • Prealbumin
  • TBPA
Gene NameTTR
OrganismHuman
Amino acid sequence
>lcl|BSEQ0010252|Transthyretin
MASHRLLLLCLAGLVFVSEAGPTGTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDT
WEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDS
GPRRYTIAALLSPYSYSTTAVVTNPKE
Number of residues147
Molecular Weight15886.88
Theoretical pI5.58
GO Classification
Functions
  • identical protein binding
  • hormone binding
Processes
  • extracellular matrix organization
  • cellular protein metabolic process
  • phototransduction, visible light
  • retinoid metabolic process
  • retinol metabolic process
  • transport
Components
  • extracellular exosome
  • cytoplasm
  • protein complex
  • extracellular region
  • extracellular space
General FunctionIdentical protein binding
Specific FunctionThyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain.
Pfam Domain Function
Transmembrane RegionsNot Available
GenBank Protein ID189582
UniProtKB IDP02766
UniProtKB Entry NameTTHY_HUMAN
Cellular LocationSecreted
Gene sequence
>lcl|BSEQ0010253|Transthyretin (TTR)
ATGGCTTCTCATCGTCTGCTCCTCCTCTGCCTTGCTGGACTGGTATTTGTGTCTGAGGCT
GGCCCTACGGGCACCGGTGAATCCAAGTGTCCTCTGATGGTCAAAGTTCTAGATGCTGTC
CGAGGCAGTCCTGCCATCAATGTGGCCGTGCATGTGTTCAGAAAGGCTGCTGATGACACC
TGGGAGCCATTTGCCTCTGGGAAAACCAGTGAGTCTGGAGAGCTGCATGGGCTCACAACT
GAGGAGGAATTTGTAGAAGGGATATACAAAGTGGAAATAGACACCAAATCTTACTGGAAG
GCACTTGGCATCTCCCCATTCCATGAGCATGCAGAGGTGGTATTCACAGCCAACGACTCC
GGCCCCCGCCGCTACACCATTGCCGCCCTGCTGAGCCCCTACTCCTATTCCACCACGGCT
GTCGTCACCAATCCCAAGGAATGA
GenBank Gene IDK02091
GeneCard IDNot Available
GenAtlas IDTTR
HGNC IDHGNC:12405
Chromosome Location18
Locus18q12.1
References
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