Chromosome-associated kinesin KIF4A
Name | Chromosome-associated kinesin KIF4A |
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Synonyms |
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Gene Name | KIF4A |
Organism | Human |
Amino acid sequence | >lcl|BSEQ0009162|Chromosome-associated kinesin KIF4A MKEEVKGIPVRVALRCRPLVPKEISEGCQMCLSFVPGEPQVVVGTDKSFTYDFVFDPSTE QEEVFNTAVAPLIKGVFKGYNATVLAYGQTGSGKTYSMGGAYTAEQENEPTVGVIPRVIQ LLFKEIDKKSDFEFTLKVSYLEIYNEEILDLLCPSREKAQINIREDPKEGIKIVGLTEKT VLVALDTVSCLEQGNNSRTVASTAMNSQSSRSHAIFTISLEQRKKSDKNSSFRSKLHLVD LAGSERQKKTKAEGDRLKEGININRGLLCLGNVISALGDDKKGGFVPYRDSKLTRLLQDS LGGNSHTLMIACVSPADSNLEETLNTLRYADRARKIKNKPIVNIDPQTAELNHLKQQVQQ LQVLLLQAHGGTLPGSITVEPSENLQSLMEKNQSLVEENEKLSRGLSEAAGQTAQMLERI ILTEQANEKMNAKLEELRQHAACKLDLQKLVETLEDQELKENVEIICNLQQLITQLSDET VACMAAAIDTAVEQEAQVETSPETSRSSDAFTTQHALRQAQMSKELVELNKALALKEALA RKMTQNDSQLQPIQYQYQDNIKELELEVINLQKEKEELVLELQTAKKDANQAKLSERRRK RLQELEGQIADLKKKLNEQSKLLKLKESTERTVSKLNQEIRMMKNQRVQLMRQMKEDAEK FRQWKQKKDKEVIQLKERDRKRQYELLKLERNFQKQSNVLRRKTEEAAAANKRLKDALQK QREVADKRKETQSRGMEGTAARVKNWLGNEIEVMVSTEEAKRHLNDLLEDRKILAQDVAQ LKEKKESGENPPPKLRRRTFSLTEVRGQVSESEDSITKQIESLETEMEFRSAQIADLQQK LLDAESEDRPKQRWENIATILEAKCALKYLIGELVSSKIQVSKLESSLKQSKTSCADMQK MLFEERNHFAEIETELQAELVRMEQQHQEKVLYLLSQLQQSQMAEKQLEESVSEKEQQLL STLKCQDEELEKMREVCEQNQQLLRENEIIKQKLTLLQVASRQKHLPKDTLLSPDSSFEY VPPKPKPSRVKEKFLEQSMDIEDLKYCSEHSVNEHEDGDGDDDEGDDEEWKPTKLVKVSR KNIQGCSCKGWCGNKQCGCRKQKSDCGVDCCCDPTKCRNRQQGKDSLGTVERTQDSEGSF KLEDPTEVTPGLSFFNPVCATPNSKILKEMCDVEQVLSKKTPPAPSPFDLPELKHVATEY QENKAPGKKKKRALASNTSFFSGCSPIEEEAH |
Number of residues | 1232 |
Molecular Weight | 139880.015 |
Theoretical pI | Not Available |
GO Classification | Functions
Processes
Components
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General Function | Microtubule motor activity |
Specific Function | Motor protein that translocates PRC1 to the plus ends of interdigitating spindle microtubules during the metaphase to anaphase transition, an essential step for the formation of an organized central spindle midzone and midbody and for successful cytokinesis. May play a role in mitotic chromosomal positioning and bipolar spindle stabilization. |
Pfam Domain Function |
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Transmembrane Regions | Not Available |
GenBank Protein ID | Not Available |
UniProtKB ID | O95239 |
UniProtKB Entry Name | KIF4A_HUMAN |
Cellular Location | Nucleus matrix |
Gene sequence | >lcl|BSEQ0013646|Chromosome-associated kinesin KIF4A (KIF4A) ATGAAGGAAGAGGTGAAGGGAATTCCTGTAAGAGTGGCGCTGCGTTGTCGCCCTCTGGTC CCCAAAGAGATTAGCGAGGGCTGCCAGATGTGCCTTTCCTTCGTGCCCGGAGAGCCTCAG GTGGTGGTTGGTACAGATAAATCCTTCACCTACGATTTTGTATTTGATCCCTCTACTGAA CAGGAAGAAGTCTTCAATACAGCAGTAGCGCCACTCATAAAAGGTGTATTTAAAGGATAT AATGCAACGGTCCTGGCCTATGGGCAGACTGGCTCTGGAAAAACCTATTCAATGGGAGGT GCATATACTGCAGAGCAAGAGAATGAACCAACAGTTGGGGTTATTCCTAGGGTAATACAA CTGCTCTTCAAAGAAATTGATAAAAAGAGTGACTTTGAATTTACTCTGAAAGTGTCTTAC TTAGAGATTTACAATGAAGAAATTTTGGATCTTCTATGCCCATCTCGTGAGAAAGCTCAA ATAAATATACGAGAGGATCCTAAGGAAGGCATAAAGATTGTGGGACTCACTGAGAAGACT GTTTTGGTTGCCTTGGATACTGTTTCCTGTTTGGAACAGGGCAACAACTCTAGGACTGTG GCCTCCACGGCTATGAACTCCCAGTCGTCCCGATCTCATGCCATCTTTACAATCTCCTTA GAGCAAAGAAAGAAAAGTGACAAGAATAGCAGCTTTCGCTCCAAGCTGCATCTTGTAGAC CTCGCTGGATCAGAAAGACAGAAGAAAACCAAGGCTGAAGGGGATCGTCTAAAAGAGGGT ATTAATATTAACCGAGGCCTCCTATGCTTGGGAAATGTAATCAGTGCTCTTGGAGATGAC AAAAAGGGTGGCTTTGTGCCCTACAGAGATTCCAAGTTGACTCGACTGCTTCAAGATTCT CTAGGAGGTAATAGCCATACTCTTATGATAGCCTGTGTGAGTCCTGCTGACTCCAATCTA GAGGAAACATTAAATACCCTTCGCTATGCTGACAGAGCAAGAAAAATCAAGAACAAACCT ATTGTTAATATTGATCCCCAGACAGCTGAACTTAATCATCTAAAGCAACAGGTACAACAG CTACAAGTCTTGTTGCTACAGGCCCATGGAGGTACCCTGCCTGGATCTATAACTGTGGAA CCATCAGAGAATCTACAATCCCTGATGGAGAAGAATCAGTCCCTGGTAGAGGAGAATGAA AAATTAAGTCGTGGTCTGAGCGAGGCAGCTGGTCAGACAGCCCAGATGTTGGAGAGGATC ATTTTGACAGAGCAAGCGAATGAAAAAATGAACGCCAAGCTAGAAGAGCTCAGGCAGCAT GCGGCCTGCAAACTGGATCTTCAAAAGCTAGTGGAGACTTTGGAAGACCAGGAATTGAAA GAAAATGTAGAGATAATTTGTAACCTGCAGCAATTGATTACCCAGTTATCGGATGAAACT GTTGCTTGCATGGCTGCAGCCATTGATACTGCGGTGGAGCAAGAAGCCCAAGTAGAAACC AGTCCAGAGACGAGCAGGTCTTCTGACGCTTTTACCACTCAGCATGCTCTCCGTCAAGCG CAGATGTCTAAGGAGCTGGTTGAGTTGAATAAAGCGCTTGCACTGAAAGAGGCCCTGGCT AGGAAGATGACTCAGAATGACAGCCAACTGCAGCCCATTCAGTACCAATACCAGGATAAC ATAAAAGAGCTAGAATTAGAAGTCATCAATCTGCAAAAGGAAAAGGAAGAATTGGTTCTT GAACTTCAGACAGCAAAGAAGGATGCCAACCAAGCCAAGTTGAGTGAGCGCCGCCGCAAA CGTCTCCAGGAGCTGGAGGGTCAAATTGCTGATCTGAAGAAGAAACTGAATGAGCAGTCC AAACTTCTGAAACTAAAGGAATCCACAGAGCGTACTGTCTCCAAACTGAACCAGGAGATA CGGATGATGAAAAACCAGCGGGTACAGTTAATGCGTCAAATGAAAGAAGATGCTGAGAAG TTTAGACAGTGGAAGCAGAAAAAAGACAAAGAAGTAATACAGTTAAAAGAACGAGACCGT AAGAGGCAATATGAGCTGCTGAAACTTGAAAGAAACTTCCAGAAACAATCCAATGTGCTC AGACGTAAAACGGAGGAGGCAGCAGCTGCCAACAAGCGTCTCAAGGATGCTCTCCAGAAA CAACGGGAGGTTGCAGATAAGCGGAAAGAGACTCAGAGCCGTGGAATGGAAGGCACTGCA GCTCGAGTGAAGAATTGGCTTGGAAACGAAATTGAGGTTATGGTCAGTACTGAGGAAGCC AAACGCCATCTGAATGACCTCCTTGAAGATAGAAAGATCCTGGCTCAAGATGTGGCTCAA CTCAAAGAAAAAAAGGAATCTGGGGAGAATCCACCTCCTAAACTCCGGAGGCGTACATTC TCCCTTACTGAAGTGCGTGGTCAAGTTTCGGAGTCAGAAGATTCTATTACAAAGCAGATT GAAAGCCTAGAGACTGAAATGGAATTCAGGAGTGCTCAGATTGCTGACCTACAGCAGAAG CTGCTGGATGCAGAAAGTGAAGACAGACCAAAACAACGCTGGGAGAATATTGCCACCATT CTGGAAGCCAAGTGTGCCCTGAAATATTTGATTGGAGAGCTGGTCTCCTCCAAAATACAG GTCAGCAAACTTGAAAGCAGCCTGAAACAGAGCAAGACCAGCTGTGCTGACATGCAGAAG ATGCTGTTTGAGGAACGAAATCATTTTGCCGAGATAGAGACAGAGTTACAAGCTGAGCTG GTCAGAATGGAGCAACAGCACCAAGAGAAGGTGCTGTACCTTCTCAGCCAGCTGCAGCAA AGCCAAATGGCAGAGAAGCAGTTAGAGGAATCAGTCAGTGAAAAGGAACAGCAGCTGCTG AGCACACTGAAGTGTCAGGATGAAGAACTTGAGAAAATGCGAGAAGTGTGTGAGCAAAAT CAGCAGCTTCTCCGAGAGAATGAAATCATCAAGCAGAAACTGACCCTCCTCCAGGTAGCC AGCAGACAGAAACATCTTCCTAAGGATACCCTTCTATCTCCAGACTCTTCTTTTGAATAT GTCCCACCTAAGCCAAAACCTTCTCGTGTTAAAGAAAAGTTCCTGGAGCAAAGCATGGAC ATCGAGGATCTAAAATATTGTTCAGAGCATTCTGTGAATGAGCATGAGGATGGTGATGGT GATGATGATGAGGGGGATGACGAGGAATGGAAGCCAACAAAATTAGTTAAGGTGTCCAGG AAGAACATCCAAGGGTGTTCCTGCAAGGGCTGGTGTGGAAACAAGCAGTGTGGGTGCAGG AAGCAAAAGTCAGACTGTGGTGTGGACTGTTGCTGTGACCCCACAAAGTGTCGGAACCGC CAGCAAGGCAAGGATAGCTTGGGCACTGTTGAACGGACCCAGGATTCCGAAGGCTCCTTC AAACTGGAGGATCCTACCGAGGTGACCCCAGGATTGAGCTTCTTTAATCCCGTCTGTGCC ACCCCCAATAGCAAGATCCTGAAAGAGATGTGCGATGTGGAGCAGGTGCTGTCAAAGAAG ACTCCCCCAGCTCCCTCCCCTTTTGACCTCCCAGAGTTGAAACATGTAGCAACAGAATAC CAAGAAAACAAGGCTCCAGGGAAGAAAAAGAAACGGGCTCTGGCCAGCAACACCAGCTTC TTCTCTGGCTGCTCCCCTATCGAAGAAGAGGCCCACTGA |
GenBank Gene ID | Not Available |
GeneCard ID | Not Available |
GenAtlas ID | Not Available |
HGNC ID | HGNC:13339 |
Chromosome Location | X |
Locus | Not Available |
References |
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