Adhesion G protein-coupled receptor L1
Name | Adhesion G protein-coupled receptor L1 |
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Synonyms |
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Gene Name | ADGRL1 |
Organism | Human |
Amino acid sequence | >lcl|BSEQ0009042|Adhesion G protein-coupled receptor L1 MARLAAVLWNLCVTAVLVTSATQGLSRAGLPFGLMRRELACEGYPIELRCPGSDVIMVEN ANYGRTDDKICDADPFQMENVQCYLPDAFKIMSQRCNNRTQCVVVAGSDAFPDPCPGTYK YLEVQYDCVPYKVEQKVFVCPGTLQKVLEPTSTHESEHQSGAWCKDPLQAGDRIYVMPWI PYRTDTLTEYASWEDYVAARHTTTYRLPNRVDGTGFVVYDGAVFYNKERTRNIVKYDLRT RIKSGETVINTANYHDTSPYRWGGKTDIDLAVDENGLWVIYATEGNNGRLVVSQLNPYTL RFEGTWETGYDKRSASNAFMVCGVLYVLRSVYVDDDSEAAGNRVDYAFNTNANREEPVSL TFPNPYQFISSVDYNPRDNQLYVWNNYFVVRYSLEFGPPDPSAGPATSPPLSTTTTARPT PLTSTASPAATTPLRRAPLTTHPVGAINQLGPDLPPATAPVPSTRRPPAPNLHVSPELFC EPREVRRVQWPATQQGMLVERPCPKGTRGIASFQCLPALGLWNPRGPDLSNCTSPWVNQV AQKIKSGENAANIASELARHTRGSIYAGDVSSSVKLMEQLLDILDAQLQALRPIERESAG KNYNKMHKRERTCKDYIKAVVETVDNLLRPEALESWKDMNATEQVHTATMLLDVLEEGAF LLADNVREPARFLAAKENVVLEVTVLNTEGQVQELVFPQEEYPRKNSIQLSAKTIKQNSR NGVVKVVFILYNNLGLFLSTENATVKLAGEAGPGGPGGASLVVNSQVIAASINKESSRVF LMDPVIFTVAHLEDKNHFNANCSFWNYSERSMLGYWSTQGCRLVESNKTHTTCACSHLTN FAVLMAHREIYQGRINELLLSVITWVGIVISLVCLAICISTFCFLRGLQTDRNTIHKNLC INLFLAELLFLVGIDKTQYEIACPIFAGLLHYFFLAAFSWLCLEGVHLYLLLVEVFESEY SRTKYYYLGGYCFPALVVGIAAAIDYRSYGTEKACWLRVDNYFIWSFIGPVSFVIVVNLV FLMVTLHKMIRSSSVLKPDSSRLDNIKSWALGAIALLFLLGLTWAFGLLFINKESVVMAY LFTTFNAFQGVFIFVFHCALQKKVHKEYSKCLRHSYCCIRSPPGGTHGSLKTSAMRSNTR YYTGTQSRIRRMWNDTVRKQTESSFMAGDINSTPTLNRGTMGNHLLTNPVLQPRGGTSPY NTLIAESVGFNPSSPPVFNSPGSYREPKHPLGGREACGMDTLPLNGNFNNSYSLRSGDFP PGDGGPEPPRGRNLADAAAFEKMIISELVHNNLRGSSSAAKGPPPPEPPVPPVPGGGGEE EAGGPGGADRAEIELLYKALEEPLLLPRAQSVLYQSDLDESESCTAEDGATSRPLSSPPG RDSLYASGANLRDSPSYPDSSPEGPSEALPPPPPAPPGPPEIYYTSRPPALVARNPLQGY YQVRRPSHEGYLAAPGLEGPGPDGDGQMQLVTSL |
Number of residues | 1474 |
Molecular Weight | 162715.375 |
Theoretical pI | Not Available |
GO Classification | Functions
Processes
Components
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General Function | Latrotoxin receptor activity |
Specific Function | Calcium-independent receptor of high affinity for alpha-latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor for TENM2 that mediates heterophilic synaptic cell-cell contact and postsynaptic specialization. Receptor propably implicated in the regulation of exocytosis (By similarity). |
Pfam Domain Function | |
Transmembrane Regions | 859-879 894-914 921-941 965-985 1003-1023 1051-1071 1076-1096 |
GenBank Protein ID | Not Available |
UniProtKB ID | O94910 |
UniProtKB Entry Name | AGRL1_HUMAN |
Cellular Location | Cell membrane |
Gene sequence | >lcl|BSEQ0021426|Adhesion G protein-coupled receptor L1 (ADGRL1) ATGGCCCGCCTAGCCGCAGTGCTCTGGAATCTGTGTGTCACCGCCGTCCTGGTCACCTCG GCCACCCAAGGCCTGAGCCGGGCCGGGCTCCCGTTCGGGCTGATGCGCCGGGAGCTGGCG TGTGAAGGCTACCCCATCGAGCTGCGGTGCCCCGGCAGCGACGTCATCATGGTGGAGAAT GCCAACTACGGGCGCACGGACGACAAGATTTGCGATGCTGACCCTTTCCAGATGGAGAAT GTGCAGTGCTACCTGCCGGACGCCTTCAAGATCATGTCACAGAGGTGTAACAACCGCACC CAGTGCGTGGTGGTCGCCGGCTCGGATGCCTTTCCTGACCCCTGTCCTGGGACCTACAAG TACCTGGAGGTGCAGTACGACTGTGTCCCCTACAAAGTGGAGCAGAAAGTCTTCGTGTGC CCAGGGACCCTGCAGAAGGTGCTGGAGCCCACCTCGACACACGAGTCAGAGCACCAGTCT GGCGCATGGTGCAAGGACCCGCTGCAGGCGGGTGACCGCATCTACGTGATGCCCTGGATC CCCTACCGCACGGACACACTGACTGAGTATGCCTCGTGGGAGGACTACGTGGCCGCCCGC CACACCACCACCTACCGCCTGCCCAACCGCGTGGATGGCACAGGCTTTGTGGTCTACGAT GGTGCCGTCTTCTACAACAAGGAGCGCACGCGCAACATCGTCAAGTATGACCTACGGACG CGCATCAAGAGCGGGGAGACGGTCATCAATACCGCCAACTACCATGACACCTCGCCCTAC CGCTGGGGCGGAAAGACCGACATTGACCTGGCGGTGGACGAGAACGGGCTGTGGGTCATC TACGCCACTGAGGGCAACAACGGGCGGCTGGTGGTGAGCCAGCTGAACCCCTACACACTG CGCTTTGAGGGCACGTGGGAGACGGGTTACGACAAGCGCTCGGCATCCAACGCCTTCATG GTGTGTGGGGTCCTGTACGTCCTGCGTTCCGTGTACGTGGATGATGACAGCGAGGCGGCT GGCAACCGCGTGGACTATGCCTTCAACACCAATGCCAACCGCGAGGAGCCTGTCAGCCTC ACCTTCCCCAACCCCTACCAGTTCATCTCCTCCGTTGACTACAACCCTCGCGACAACCAG CTGTACGTCTGGAACAACTATTTCGTGGTGCGCTACAGCCTGGAGTTCGGGCCGCCCGAC CCCAGTGCTGGCCCAGCCACTTCCCCACCCCTCAGCACGACCACCACAGCCAGGCCCACG CCCCTCACCAGCACAGCCTCGCCCGCAGCCACCACCCCGCTCCGCCGGGCACCCCTCACC ACGCACCCAGTGGGTGCCATCAACCAGCTGGGACCTGATCTGCCTCCAGCCACAGCCCCA GTCCCCAGCACCCGGCGGCCCCCAGCCCCGAATCTACACGTGTCCCCTGAGCTCTTCTGC GAGCCCCGAGAGGTACGGCGGGTCCAGTGGCCGGCCACCCAGCAGGGCATGCTGGTGGAG AGGCCCTGCCCCAAGGGGACTCGAGGAATTGCCTCCTTCCAGTGTCTACCAGCCTTGGGG CTCTGGAACCCCCGGGGCCCTGACCTCAGCAACTGCACCTCCCCCTGGGTCAACCAGGTG GCCCAGAAGATCAAGAGTGGGGAGAACGCGGCCAACATCGCCAGCGAGCTGGCCCGACAC ACCCGGGGCTCCATCTACGCGGGGGACGTCTCCTCCTCTGTGAAGCTGATGGAGCAGCTG CTGGACATCCTGGATGCCCAGCTGCAGGCCCTGCGGCCCATCGAGCGCGAGTCAGCCGGC AAGAACTACAACAAGATGCACAAGCGAGAGAGAACTTGTAAGGATTATATCAAGGCCGTG GTGGAGACAGTGGACAATCTGCTCCGGCCAGAAGCTCTGGAGTCCTGGAAGGACATGAAT GCCACGGAGCAGGTGCACACGGCCACCATGCTCCTCGACGTCCTGGAGGAGGGCGCCTTC CTGCTGGCCGACAATGTCAGGGAGCCTGCCCGCTTCCTGGCTGCCAAGGAGAACGTGGTC CTGGAGGTCACAGTCCTGAACACAGAGGGCCAGGTGCAGGAGCTGGTGTTCCCCCAGGAG GAGTACCCGAGAAAGAACTCCATCCAGCTGTCTGCCAAAACCATCAAGCAGAACAGCCGC AATGGGGTGGTCAAAGTTGTCTTCATCCTCTACAACAACCTGGGCCTCTTCCTGTCCACG GAGAATGCCACAGTGAAGCTGGCCGGCGAAGCAGGCCCGGGTGGCCCTGGGGGCGCCTCT CTAGTGGTGAACTCACAGGTCATCGCAGCATCCATCAACAAGGAGTCCAGCCGCGTCTTC CTCATGGACCCTGTCATCTTCACCGTGGCCCACCTGGAGGACAAGAACCACTTCAATGCT AACTGCTCCTTCTGGAACTACTCGGAGCGTTCCATGCTGGGCTACTGGTCGACCCAAGGC TGCCGCCTGGTGGAGTCCAACAAGACCCATACCACGTGTGCCTGCAGCCACCTCACCAAC TTCGCTGTGCTCATGGCTCACCGTGAGATCTACCAGGGCCGCATCAACGAGCTGCTGCTG TCGGTCATCACCTGGGTGGGCATTGTGATCTCCCTGGTCTGCTTGGCCATCTGCATCTCC ACCTTCTGCTTCCTGCGGGGGCTGCAGACCGACCGCAACACCATCCACAAGAACCTGTGC ATCAACCTCTTCCTGGCTGAGCTGCTCTTCCTGGTCGGGATCGACAAGACTCAGTATGAG ATTGCCTGCCCCATCTTCGCCGGCCTGCTGCACTATTTCTTCCTGGCTGCCTTCTCCTGG CTGTGCCTGGAGGGCGTGCACCTCTACCTGCTACTAGTGGAGGTGTTTGAGAGCGAGTAT TCCCGCACCAAGTACTACTACCTGGGTGGCTACTGCTTCCCGGCCCTGGTGGTGGGCATC GCGGCTGCCATTGACTACCGCAGCTACGGCACCGAGAAGGCCTGCTGGCTCCGAGTGGAC AATTACTTCATCTGGAGTTTCATCGGGCCAGTCTCCTTCGTTATCGTGGTCAACCTGGTG TTCCTCATGGTGACCCTGCACAAGATGATCCGAAGCTCATCTGTGCTCAAGCCCGACTCC AGCCGCCTGGACAACATTAAATCCTGGGCGCTGGGGGCCATCGCGCTGCTGTTCCTGCTG GGCCTCACCTGGGCTTTCGGCCTCCTCTTCATCAACAAGGAGTCGGTGGTCATGGCCTAT CTCTTCACCACCTTCAACGCCTTCCAGGGGGTCTTCATCTTCGTCTTTCACTGCGCCTTA CAGAAGAAGGTGCACAAGGAGTACAGCAAGTGCCTGCGTCACTCCTACTGCTGCATCCGC TCCCCACCCGGGGGCACTCACGGATCCCTCAAGACCTCAGCCATGCGAAGCAACACCCGC TACTACACAGGGACCCAGAGCCGAATTCGGAGGATGTGGAATGACACTGTGAGGAAACAG ACGGAGTCCTCCTTCATGGCGGGTGACATCAACAGCACCCCCACCCTGAACCGAGGTACC ATGGGGAACCACCTGCTGACCAACCCCGTGCTGCAGCCCCGTGGGGGCACCAGTCCCTAC AACACCCTCATCGCCGAGTCAGTGGGCTTCAATCCCTCCTCGCCCCCTGTCTTCAACTCC CCAGGGAGCTACCGGGAACCCAAGCACCCCTTGGGAGGCCGGGAAGCCTGTGGCATGGAC ACCCTGCCCCTGAACGGCAACTTCAATAACAGTTACTCCTTGCGAAGTGGGGATTTCCCT CCCGGGGATGGGGGCCCTGAGCCGCCCCGAGGCCGGAACCTAGCCGATGCGGCGGCCTTT GAGAAGATGATCATCTCAGAGCTGGTGCACAACAACCTGCGGGGGAGCAGCAGCGCGGCC AAGGGCCCTCCACCGCCTGAGCCCCCTGTGCCACCTGTGCCAGGGGGCGGGGGCGAGGAA GAGGCGGGCGGGCCCGGGGGTGCTGACCGGGCCGAGATTGAACTTCTCTATAAGGCCCTG GAGGAGCCTCTGCTGCTGCCCCGGGCCCAGTCGGTGCTGTACCAGAGCGATCTGGACGAG TCGGAGAGCTGCACGGCCGAGGACGGCGCCACCAGCCGGCCCCTCTCCTCCCCTCCTGGC CGGGACTCCCTCTATGCCAGCGGGGCCAACCTGCGGGACTCACCCTCCTACCCGGACAGC AGCCCTGAGGGGCCCAGTGAGGCCCTGCCCCCACCCCCTCCCGCACCCCCCGGCCCCCCC GAAATCTACTACACCTCGCGCCCGCCAGCCCTGGTGGCCCGGAATCCCCTGCAGGGCTAC TACCAGGTGCGGCGTCCTAGCCACGAGGGCTACCTGGCAGCCCCAGGCCTTGAGGGGCCA GGGCCCGATGGGGACGGGCAGATGCAGCTGGTCACCAGTCTCTGA |
GenBank Gene ID | Not Available |
GeneCard ID | Not Available |
GenAtlas ID | Not Available |
HGNC ID | HGNC:20973 |
Chromosome Location | 19 |
Locus | Not Available |
References |
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