NameProtein arginine N-methyltransferase 3
Synonyms
  • 2.1.1.-
  • Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 3
  • HRMT1L3
Gene NamePRMT3
OrganismHuman
Amino acid sequence
>lcl|BSEQ0009367|Protein arginine N-methyltransferase 3
MCSLASGATGGRGAVENEEDLPELSDSGDEAAWEDEDDADLPHGKQQTPCLFCNRLFTSA
EETFSHCKSEHQFNIDSMVHKHGLEFYGYIKLINFIRLKNPTVEYMNSIYNPVPWEKEEY
LKPVLEDDLLLQFDVEDLYEPVSVPFSYPNGLSENTSVVEKLKHMEARALSAEAALARAR
EDLQKMKQFAQDFVMHTDVRTCSSSTSVIADLQEDEDGVYFSSYGHYGIHEEMLKDKIRT
ESYRDFIYQNPHIFKDKVVLDVGCGTGILSMFAAKAGAKKVLGVDQSEILYQAMDIIRLN
KLEDTITLIKGKIEEVHLPVEKVDVIISEWMGYFLLFESMLDSVLYAKNKYLAKGGSVYP
DICTISLVAVSDVNKHADRIAFWDDVYGFKMSCMKKAVIPEAVVEVLDPKTLISEPCGIK
HIDCHTTSISDLEFSSDFTLKITRTSMCTAIAGYFDIYFEKNCHNRVVFSTGPQSTKTHW
KQTVFLLEKPFSVKAGEALKGKVTVHKSKKDPRSLTVTLTLNNSTQTYGLQ
Number of residues531
Molecular Weight59875.63
Theoretical pINot Available
GO Classification
Functions
  • methyltransferase activity
  • metal ion binding
  • histone-arginine N-methyltransferase activity
  • protein-arginine N-methyltransferase activity
  • protein-arginine omega-N asymmetric methyltransferase activity
Processes
  • regulation of transcription, DNA-templated
  • negative regulation of protein ubiquitination
  • histone arginine methylation
  • peptidyl-arginine methylation, to asymmetrical-dimethyl arginine
Components
  • cytoplasm
  • ribosome
  • cytosol
General FunctionProtein-arginine omega-n asymmetric methyltransferase activity
Specific FunctionMethylates (mono and asymmetric dimethylation) the guanidino nitrogens of arginyl residues in some proteins.
Pfam Domain FunctionNot Available
Transmembrane RegionsNot Available
GenBank Protein IDNot Available
UniProtKB IDO60678
UniProtKB Entry NameANM3_HUMAN
Cellular LocationCytoplasm
Gene sequenceNot Available
GenBank Gene IDNot Available
GeneCard IDNot Available
GenAtlas IDNot Available
HGNC IDHGNC:30163
Chromosome LocationNot Available
LocusNot Available
References
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