Monocarboxylate transporter 5
Name | Monocarboxylate transporter 5 |
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Synonyms |
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Gene Name | SLC16A4 |
Organism | Human |
Amino acid sequence | >lcl|BSEQ0000389|Monocarboxylate transporter 5 MLKREGKVQPYTKTLDGGWGWMIVIHFFLVNVFVMGMTKTFAIFFVVFQEEFEGTSEQIG WIGSIMSSLRFCAGPLVAIICDILGEKTTSILGAFVVTGGYLISSWATSIPFLCVTMGLL PGLGSAFLYQVAAVVTTKYFKKRLALSTAIARSGMGLTFLLAPFTKFLIDLYDWTGALIL FGAIALNLVPSSMLLRPIHIKSENNSGIKDKGSSLSAHGPEAHATETHCHETEESTIKDS TTQKAGLPSKNLTVSQNQSEEFYNGPNRNRLLLKSDEESDKVISWSCKQLFDISLFRNPF FYIFTWSFLLSQLAYFIPTFHLVARAKTLGIDIMDASYLVSVAGILETVSQIISGWVADQ NWIKKYHYHKSYLILCGITNLLAPLATTFPLLMTYTICFAIFAGGYLALILPVLVDLCRN STVNRFLGLASFFAGMAVLSGPPIAGWLYDYTQTYNGSFYFSGICYLLSSVSFFFVPLAE RWKNSLT |
Number of residues | 487 |
Molecular Weight | 54021.43 |
Theoretical pI | 8.13 |
GO Classification | Functions
Processes
Components
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General Function | Symporter activity |
Specific Function | Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate (By similarity). |
Pfam Domain Function |
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Transmembrane Regions | 17-37 60-80 88-108 110-129 144-164 175-195 300-320 338-358 373-393 395-415 426-446 459-479 |
GenBank Protein ID | 2463628 |
UniProtKB ID | O15374 |
UniProtKB Entry Name | MOT5_HUMAN |
Cellular Location | Cell membrane |
Gene sequence | >lcl|BSEQ0016030|Monocarboxylate transporter 5 (SLC16A4) ATGCTGAAGAGGGAGGGGAAGGTCCAACCTTACACTAAAACCCTGGATGGAGGATGGGGA TGGATGATTGTGATTCATTTTTTCCTGGTGAATGTGTTTGTGATGGGGATGACCAAGACT TTTGCAATTTTCTTTGTGGTCTTTCAAGAAGAGTTTGAAGGCACCTCAGAGCAAATTGGT TGGATTGGATCCATCATGTCATCTCTTCGTTTTTGTGCAGGTTTGGGTTCTGCTTTCTTA TACCAAGTGGCTGCTGTGGTAACTACCAAATACTTCAAAAAACGATTGGCTCTTTCTACA GCTATTGCCCGTTCTGGGATGGGACTGACTTTTCTTTTGGCACCCTTTACAAAATTCCTG ATAGATCTGTATGACTGGACAGGAGCCCTTATATTATTTGGAGCTATCGCATTGAATTTG GTGCCTTCTAGTATGCTCTTAAGACCCATCCATATCAAAAGTGAGAACAATTCTGGTATT AAAGATAAAGGCAGCAGTTTGTCTGCACATGGTCCAGAGGCACATGCAACAGAAACACAC TGCCATGAGACAGAAGAGTCTACCATCAAGGACAGTACTACGCAGAAGGCTGGACTACCT AGCAAAAATTTAACAGTCTCACAAAATCAAAGTGAAGAGTTCTACAATGGGCCTAACAGG AACAGACTGTTATTAAAGAGTGATGAAGAAAGTGATAAGGTTATTTCGTGGAGCTGCAAA CAACTGTTTGACATTTCTCTCTTTAGAAATCCTTTCTTCTACATATTTACTTGGTCTTTT CTCCTCAGTCAGTTAGCATACTTCATCCCTACCTTTCACCTGGTAGCCAGAGCCAAAACA CTGGGGATTGACATCATGGATGCCTCTTACCTTGTTTCTGTAGCAGGTATCCTTGAGACG GTCAGTCAGATTATTTCTGGATGGGTTGCTGATCAAAACTGGATTAAGAAGTATCATTAC CACAAGTCTTACCTCATCCTCTGCGGCATCACTAACCTGCTTGCTCCTTTAGCCACCACA TTTCCACTACTTATGACCTACACCATCTGCTTTGCCATCTTTGCTGGTGGTTACCTGGCA TTGATACTGCCTGTACTGGTTGATCTGTGTAGGAATTCTACAGTAAACAGGTTTTTGGGA CTTGCCAGTTTCTTTGCTGGGATGGCTGTCCTTTCTGGACCACCTATAGCAGGCTGGTTA TATGATTATACCCAGACATACAATGGCTCTTTCTACTTCTCTGGCATATGCTATCTCCTC TCTTCAGTTTCCTTTTTTTTTGTACCATTGGCCGAAAGATGGAAAAACAGTCTGACCTGA |
GenBank Gene ID | U59185 |
GeneCard ID | Not Available |
GenAtlas ID | SLC16A4 |
HGNC ID | HGNC:10925 |
Chromosome Location | 1 |
Locus | 1p13.3 |
References |
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