NameMicrosomal glutathione S-transferase 3
Synonyms
  • 2.5.1.18
  • Microsomal GST-3
  • Microsomal GST-III
Gene NameMGST3
OrganismHuman
Amino acid sequence
>lcl|BSEQ0011641|Microsomal glutathione S-transferase 3
MAVLSKEYGFVLLTGAASFIMVAHLAINVSKARKKYKVEYPIMYSTDPENGHIFNCIQRA
HQNTLEVYPPFLFFLAVGGVYHPRIASGLGLAWIVGRVLYAYGYYTGEPSKRSRGALGSI
ALLGLVGTTVCSAFQHLGWVKSGLGSGPKCCH
Number of residues152
Molecular Weight16516.185
Theoretical pI9.68
GO Classification
Functions
  • glutathione transferase activity
  • glutathione peroxidase activity
  • peroxidase activity
Processes
  • small molecule metabolic process
  • lipid metabolic process
  • xenobiotic metabolic process
  • glutathione derivative biosynthetic process
  • response to organonitrogen compound
  • signal transduction
Components
  • endoplasmic reticulum membrane
  • integral component of membrane
  • extracellular exosome
  • intracellular membrane-bounded organelle
  • nuclear envelope
  • membrane
General FunctionPeroxidase activity
Specific FunctionAlso functions as a glutathione peroxidase.
Pfam Domain Function
Transmembrane Regions9-29 71-91 120-140
GenBank Protein ID2583081
UniProtKB IDO14880
UniProtKB Entry NameMGST3_HUMAN
Cellular LocationEndoplasmic reticulum membrane
Gene sequence
>lcl|BSEQ0011642|Microsomal glutathione S-transferase 3 (MGST3)
ATGGCTGTCCTCTCTAAGGAATATGGTTTTGTGCTTCTAACTGGTGCTGCCAGCTTTATA
ATGGTGGCCCACCTAGCCATCAATGTTTCCAAGGCCCGCAAGAAGTACAAAGTGGAGTAT
CCTATCATGTACAGCACGGACCCTGAAAATGGGCACATCTTCAACTGCATTCAGCGAGCC
CACCAGAACACGTTGGAAGTGTATCCTCCCTTCTTATTTTTTCTAGCTGTTGGAGGTGTT
TACCACCCGCGTATAGCTTCTGGCCTGGGCTTGGCCTGGATTGTTGGACGAGTTCTTTAT
GCTTATGGCTATTACACGGGAGAACCCAGCAAGCGTAGTCGAGGAGCCCTGGGGTCCATC
GCCCTCCTGGGCTTGGTGGGCACAACTGTGTGCTCTGCTTTCCAGCATCTTGGTTGGGTT
AAAAGTGGCTTGGGCAGTGGACCCAAATGCTGCCATTAA
GenBank Gene IDAF026977
GeneCard IDNot Available
GenAtlas IDMGST3
HGNC IDHGNC:7064
Chromosome Location1
Locus1q23
References
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