Kinesin-like protein KIF2A
Name | Kinesin-like protein KIF2A |
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Synonyms |
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Gene Name | KIF2A |
Organism | Human |
Amino acid sequence | >lcl|BSEQ0009158|Kinesin-like protein KIF2A MATANFGKIQIGIYVEIKRSDGRIHQAMVTSLNEDNESVTVEWIENGDTKGKEIDLESIF SLNPDLVPDEEIEPSPETPPPPASSAKVNKIVKNRRTVASIKNDPPSRDNRVVGSARARP SQFPEQSSSAQQNGSVSDISPVQAAKKEFGPPSRRKSNCVKEVEKLQEKREKRRLQQQEL REKRAQDVDATNPNYEIMCMIRDFRGSLDYRPLTTADPIDEHRICVCVRKRPLNKKETQM KDLDVITIPSKDVVMVHEPKQKVDLTRYLENQTFRFDYAFDDSAPNEMVYRFTARPLVET IFERGMATCFAYGQTGSGKTHTMGGDFSGKNQDCSKGIYALAARDVFLMLKKPNYKKLEL QVYATFFEIYSGKVFDLLNRKTKLRVLEDGKQQVQVVGLQEREVKCVEDVLKLIDIGNSC RTSGQTSANAHSSRSHAVFQIILRRKGKLHGKFSLIDLAGNERGADTSSADRQTRLEGAE INKSLLALKECIRALGRNKPHTPFRASKLTQVLRDSFIGENSRTCMIATISPGMASCENT LNTLRYANRVKELTVDPTAAGDVRPIMHHPPNQIDDLETQWGVGSSPQRDDLKLLCEQNE EEVSPQLFTFHEAVSQMVEMEEQVVEDHRAVFQESIRWLEDEKALLEMTEEVDYDVDSYA TQLEAILEQKIDILTELRDKVKSFRAALQEEEQASKQINPKRPRAL |
Number of residues | 706 |
Molecular Weight | 79953.875 |
Theoretical pI | Not Available |
GO Classification | Functions
Processes
Components
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General Function | Motor activity |
Specific Function | Plus end-directed microtubule-dependent motor required for normal brain development. May regulate microtubule dynamics during axonal growth. Required for normal progression through mitosis. Required for normal congress of chromosomes at the metaphase plate. Required for normal spindle dynamics during mitosis. Promotes spindle turnover. Implicated in formation of bipolar mitotic spindles. Has microtubule depolymerization activity. |
Pfam Domain Function |
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Transmembrane Regions | Not Available |
GenBank Protein ID | Not Available |
UniProtKB ID | O00139 |
UniProtKB Entry Name | KIF2A_HUMAN |
Cellular Location | Cytoplasm |
Gene sequence | >lcl|BSEQ0013645|Kinesin-like protein KIF2A (KIF2A) ATGGCAACGGCCAACTTCGGCAAGATCCAGATCGGGATTTACGTGGAGATCAAGCGCAGC GATGGCCGAATACATCAAGCAATGGTAACATCTTTAAATGAAGATAATGAAAGTGTAACT GTTGAATGGATAGAAAATGGAGATACAAAAGGCAAAGAGATTGACCTGGAGAGCATCTTT TCACTTAACCCTGACCTTGTTCCTGATGAAGAAATTGAACCCAGTCCAGAAACACCTCCA CCTCCAGCATCCTCAGCCAAAGTAAACAAAATTGTAAAGAATCGACGGACTGTAGCTTCT ATTAAGAATGACCCTCCTTCAAGAGATAATAGAGTGGTTGGTTCAGCACGTGCACGGCCC AGTCAATTTCCTGAACAGTCTTCCTCTGCACAACAGAATGGTAGTGTTTCAGATATATCT CCAGTTCAAGCTGCAAAAAAGGAATTTGGACCCCCTTCACGTAGAAAATCTAATTGTGTG AAAGAAGTAGAAAAACTGCAAGAAAAACGAGAGAAAAGGAGATTGCAACAGCAAGAACTT AGAGAAAAAAGAGCCCAGGACGTTGATGCTACAAACCCAAATTATGAAATTATGTGTATG ATCAGAGACTTTAGAGGAAGTTTGGATTATAGACCATTAACAACAGCAGATCCTATTGAT GAACATAGGATATGTGTGTGTGTAAGAAAACGACCACTCAATAAAAAAGAAACTCAAATG AAAGATCTTGATGTAATCACAATTCCTAGTAAAGATGTTGTGATGGTACATGAACCAAAA CAAAAAGTAGATTTAACAAGGTACCTAGAAAACCAAACATTTCGTTTTGATTATGCCTTT GATGACTCAGCTCCTAATGAAATGGTTTACAGGTTTACTGCTAGACCACTAGTGGAAACT ATATTTGAAAGGGGAATGGCTACATGCTTTGCTTATGGGCAGACTGGAAGTGGAAAAACT CATACTATGGGTGGTGACTTTTCAGGAAAGAACCAAGATTGTTCTAAAGGAATTTATGCA TTAGCAGCTCGAGATGTCTTTTTAATGCTAAAGAAGCCAAACTATAAGAAGCTAGAACTT CAAGTATATGCAACCTTCTTTGAAATTTATAGTGGAAAGGTGTTTGACTTGCTAAACAGG AAAACAAAATTAAGAGTTCTAGAAGATGGAAAACAGCAGGTTCAAGTGGTGGGATTACAG GAACGGGAGGTCAAATGTGTTGAAGATGTACTGAAACTCATTGACATAGGCAACAGTTGC AGAACATCCGGTCAAACATCTGCAAATGCACATTCATCTCGGAGCCATGCAGTGTTTCAG ATTATTCTTAGAAGGAAAGGAAAACTACATGGCAAATTTTCTCTCATTGATTTGGCTGGA AATGAAAGAGGAGCTGATACTTCCAGTGCGGACAGGCAAACTAGGCTTGAAGGTGCTGAA ATTAATAAAAGCCTTTTAGCACTCAAGGAGTGCATCAGAGCCTTAGGTAGAAATAAACCT CATACTCCTTTCCGTGCAAGTAAACTCACTCAGGTGTTAAGAGATTCTTTCATAGGTGAA AACTCTCGTACCTGCATGATTGCCACAATCTCTCCAGGAATGGCATCCTGTGAAAATACT CTTAATACATTAAGATATGCAAATAGAGTAAAGGAGTTTGGAATTAGTCCATCAGACATT CCCTTCTCACAGGGTAGTGGCAGTCGCCCTGATCTCTCTCCTTCTTATGAATATGACGAC TTTTCTCCTTCAGTTACCAGGGTCAAAGAATTGACTGTAGATCCAACTGCTGCTGGTGAT GTTCGTCCAATAATGCACCATCCACCAAACCAGATTGATGACTTAGAGACACAGTGGGGT GTGGGGAGTTCCCCTCAGAGAGATGATCTAAAACTTCTTTGTGAACAAAATGAAGAAGAA GTCTCTCCACAGTTGTTTACTTTCCACGAAGCTGTTTCACAAATGGTAGAAATGGAAGAA CAAGTTGTAGAAGATCACAGGGCAGTGTTCCAGGAATCTATTCGGTGGTTAGAAGATGAA AAGGCCCTCTTAGAGATGACTGAAGAAGTAGATTATGATGTCGATTCATATGCTACACAA CTTGAAGCTATTCTTGAGCAAAAAATAGACATTTTAACTGAACTGCGGGATAAAGTGAAA TCTTTCCGTGCAGCTCTACAAGAGGAGGAACAAGCCAGCAAGCAAATCAACCCGAAGAGA CCCCGTGCCCTTTAA |
GenBank Gene ID | Not Available |
GeneCard ID | Not Available |
GenAtlas ID | Not Available |
HGNC ID | HGNC:6318 |
Chromosome Location | 5 |
Locus | Not Available |
References |
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