Browsing Toxins
Displaying toxin 2976 - 3000 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D0836 | Methoxsalen 298-81-7 | C12H8O4 216.190 g/mol |  |
| Methoxsalen is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholinest...more Number of Targets: 5 |
| T3D0834 | Bergamottin 7380-40-7 | C21H22O4 338.397 g/mol |  |
| Bergamottin is a potent chemopreventive agent against aflatoxin B1-inducible cyotoxicity in H4IIE cells with a bifunctional effects on glutathione S-transferase and CY...more Number of Targets: 3 |
| T3D0831 | Isoimperatorin 482-45-1 | C16H14O4 270.280 g/mol |  |
| Isoimperatorin is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholin...more Number of Targets: 4 |
| T3D0825 | Psoralen 66-97-7 | C11H6O3 186.164 g/mol |  |
| The mechanism of action many furocoumarins is based on their ability to form photoadducts with DNA and other cellular components such as RNA, proteins, and several pro...more Number of Targets: 4 |
| T3D0822 | Pimpinellin 131-12-4 | C13H10O5 246.216 g/mol |  |
| Pimpinellin acts as antagonist of proteins with GABA receptor activity (L579). The mechanism of action many furocoumarins is based on their ability to form photoadduct...more Number of Targets: 3 |
| T3D0821 | Heratomin 61265-06-3 | C16H14O4 270.280 g/mol |  |
| The mechanism of action many furocoumarins is based on their ability to form photoadducts with DNA and other cellular components such as RNA, proteins, and several pro...more Number of Targets: 3 |
| T3D0819 | Sphondin 483-66-9 | C12H8O4 216.190 g/mol |  |
| Sphondin possesses an inhibitory effect on IL-1b-induced COX-2 protein expression and PGE2 release in human pulmonary epithelial cell line (A549). The mechanism of act...more Number of Targets: 3 |
| T3D0816 | Isobergapten 482-48-4 | C12H8O4 216.190 g/mol |  |
| Inhibits insect cytochrome P450 (L579). The mechanism of action many furocoumarins is based on their ability to form photoadducts with DNA and other cellular component...more Number of Targets: 3 |
| T3D0815 | Angelicin 523-50-2 | C11H6O3 186.164 g/mol |  |
| The mechanism of action many furocoumarins is based on their ability to form photoadducts with DNA and other cellular components such as RNA, proteins, and several pro...more Number of Targets: 4 |
| T3D0813 | Amygdalin 29883-15-6 | C20H27NO11 457.429 g/mol |  |
| Amygdalin can be metabolized into hydrogen cyanide in the stomach causing discomfort or illness. (L402) Organic nitriles decompose into cyanide ions both in vivo and i...more Number of Targets: 0 |
| T3D0812 | Glufosinate 51276-47-2 | C5H12NO4P 181.127 g/mol |  |
| Glufosinate irreversibly inhibits the enzyme glutamine synthetase, which decreases ammonia detoxification. Increased ammonia levels lead to impairment of photorespirat...more Number of Targets: 1 |
| T3D0811 | Acetochlor 34256-82-1 | C14H20ClNO2 269.767 g/mol |  |
| Its mode of action is elongase inhibition, and inhibition of geranylgeranyl pyrophosphate (GGPP) cyclisation enzymes (L920). Number of Targets: 23 |
| T3D0810 | Alachlor 15972-60-8 | C14H20ClNO2 269.767 g/mol |  |
| Its mode of action is elongase inhibition, and inhibition of geranylgeranyl pyrophosphate (GGPP) cyclisation enzymes. It is also know to inhibit biosynthesis of fatty...more Number of Targets: 26 |
| T3D0808 | Paraquat dichloride 1910-42-5 | C12H14Cl2N2 257.159 g/mol |  |
| The mechanisms of the toxic effects of paraquat are largely the result of a metabolically catalyzed single electron oxidation reduction reaction, resulting in depletio...more Number of Targets: 4 |
| T3D0807 | Dicamba 1918-00-9 | C8H6Cl2O3 221.037 g/mol |  |
| Not Available Number of Targets: 5 |
| T3D0806 | Methylchlorophenoxypropionic acid 93-65-2 | C10H11ClO3 214.646 g/mol |  |
| CDDs cause their toxic effects by binding to the aryl hydrocarbon receptor and subsequently altering the trascription of certain genes. The affinity for the Ah recepto...more Number of Targets: 3 |
| T3D0805 | 4-(4-Chloro-2-methylphenoxy)butanoic acid 94-81-5 | C11H13ClO3 228.672 g/mol |  |
| Not Available Number of Targets: 3 |
| T3D0804 | 2-Methyl-4-chlorophenoxyacetic acid 94-74-6 | C9H9ClO3 200.619 g/mol |  |
| CDDs cause their toxic effects by binding to the aryl hydrocarbon receptor and subsequently altering the trascription of certain genes. The affinity for the Ah recepto...more Number of Targets: 6 |
| T3D0803 | 2,4,5-Trichlorophenoxyacetic acid 93-76-5 | C8H5Cl3O3 255.483 g/mol |  |
| CDDs cause their toxic effects by binding to the aryl hydrocarbon receptor and subsequently altering the trascription of certain genes. The affinity for the Ah recepto...more Number of Targets: 3 |
| T3D0802 | 2,4-Dichlorophenoxybutyric acid 94-82-6 | C10H10Cl2O3 249.091 g/mol |  |
| Some of the endocrine effects of 2,4-DB may be mediated by the 2,4-D mediated displacement of sex hormones from the sex hormone binding globulin or the 2,4-D mediated ...more Number of Targets: 9 |
| T3D0801 | Dichlorprop 120-36-5 | C9H8Cl2O3 235.064 g/mol |  |
| CDDs cause their toxic effects by binding to the aryl hydrocarbon receptor and subsequently altering the trascription of certain genes. The affinity for the Ah recepto...more Number of Targets: 6 |
| T3D0800 | Rotenone 83-79-4 | C20H18O6 354.353 g/mol |  |
| Rotenone works by interfering with the electron transport chain in mitochondria. Specifically, it inhibits the transfer of electrons from iron-sulfur centers in comple...more Number of Targets: 47 |
| T3D0799 | Nicotine 54-11-5 | C10H14N2 162.232 g/mol |  |
| Nicotine is a stimulant drug that acts as an agonist at nicotinic acetylcholine receptors. These are ionotropic receptors composed up of five homomeric or heteromeric ...more Number of Targets: 22 |
| T3D0798 | Fipronil 120068-37-3 | C12H4Cl2F6N4OS 437.148 g/mol |  |
| Fipronil blocks the passage of chloride ions through the GABA-regulated chloride channel, disrupting CNS activity. (T10) Organic nitriles decompose into cyanide ions b...more Number of Targets: 29 |
| T3D0797 | Imidacloprid 105827-78-9 | C9H10ClN5O2 255.661 g/mol |  |
| Imidacloprid acts on the nicotinic acetylcholine receptor; the chlorination inhibits degradation by acetylcholine-esterase (L1130). Number of Targets: 12 |