Browsing Toxins
Displaying toxin 776 - 800 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D3944 | 2-Tert-butylphenol 88-18-6 | C10H14O 150.218 g/mol |  |
| Not Available Number of Targets: 5 |
| T3D4881 | 4-tert-Butylphenol 98-54-4 | C10H14O 150.218 g/mol |  |
| 4-Tert-butylphenol is structurally similar to the melanin precursor tyrosine, and acts as a substrate for tyrosinase. Tyrosinase oxidizes 4-tert-butylphenol to a quino...more Number of Targets: 3 |
| T3D0373 | Cadmium fluoride 7790-79-6 | CdF2 150.408 g/mol |  |
| Cadmium initially binds to metallothionein and is transported to the kidney. Toxic effects are observed once the concentration of cadmium exceeds that of available met...more Number of Targets: 19 |
| T3D1234 | Tin(IV) oxide 18282-10-5 | O2Sn 150.710 g/mol |  |
| Inorganic and organic tin compounds are weak inhibitors of alcohol dehydrogenase. (A183) Number of Targets: 7 |
| T3D1273 | Tin(II) sulfide 1314-95-0 | SSn 150.770 g/mol |  |
| Inorganic and organic tin compounds are weak inhibitors of alcohol dehydrogenase. (A183) Number of Targets: 7 |
| T3D1718 | Sodium bromate 7789-38-0 | BrNaO3 150.892 g/mol |  |
| Bromine is a powerful oxidizing agent and is able to release oxygen free radicals from the water in mucous membranes. These free radicals are also potent oxidizers and...more Number of Targets: 6 |
| T3D1131 | Manganese sulfate 7785-87-7 | MnO4S 151.001 g/mol |  |
| Manganese is a cellular toxicant that can impair transport systems, enzyme activities, and receptor functions. It primarily targets the central nervous system, particu...more Number of Targets: 5 |
| T3D4652 | Bromomethyl ethyl ketone 816-40-0 | C4H7BrO 151.002 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D1199 | Copper(I) acetylide 1117-94-8 | C2Cu2 151.113 g/mol |  |
| Excess copper is sequestered within hepatocyte lysosomes, where it is complexed with metallothionein. Copper hepatotoxicity is believed to occur when the lysosomes bec...more Number of Targets: 6 |
| T3D2571 | Acetaminophen 103-90-2 | C8H9NO2 151.163 g/mol |  |
| Paracetamol toxicity is one of the most common causes of poisoning worldwide. The toxic effects of acetaminophen are due to a minor alkylating metabolite (N-acetyl-p-b...more Number of Targets: 31 |
| T3D4861 | 1,2-Benzisothiazol-3(2H)-one 2634-33-5 | C7H5NOS 151.186 g/mol |  |
| Not Available Number of Targets: 6 |
| T3D2560 | Amantadine 768-94-5 | C10H17N 151.249 g/mol |  |
| The mechanism of its antiparkinsonic effect is not fully understood, but it appears to be releasing dopamine from the nerve endings of the brain cells, together with s...more Number of Targets: 5 |
| T3D1467 | Diisopropylzinc 625-81-0 | C6H14Zn 151.584 g/mol |  |
| Anaemia results from the excessive absorption of zinc suppressing copper and iron absorption, most likely through competitive binding of intestinal mucosal cells. Unba...more Number of Targets: 1 |
| T3D1833 | Germanium selenide 12065-10-0 | GeSe 151.600 g/mol |  |
| Selenium readily substitutes for sulfur in biomolecules and in many biochemical reactions, especially when the concentration of selenium is high and the concentration ...more Number of Targets: 0 |
| T3D1444 | Chromium(III) oxide 1308-38-9 | Cr2O3 151.990 g/mol |  |
| Trivalent chromium may also form complexes with peptides, proteins, and DNA, resulting in DNA-protein crosslinks, DNA strand breaks, DNA-DNA interstrand crosslinks, ch...more Number of Targets: 5 |
| T3D0714 | Ammonium chromate 7788-98-9 | CrH8N2O4 152.071 g/mol |  |
| Hexavalent chromium's carcinogenic effects are caused by its metabolites, pentavalent and trivalent chromium. The DNA damage may be caused by hydroxyl radicals produce...more Number of Targets: 5 |
| T3D4409 | Xanthine 69-89-6 | C5H4N4O2 152.111 g/mol |  |
| Xanthine is a poorly soluble compound. As a result high concentrations of serum xanthine can lead to the formation of kidney stones (xanthine kidney stones) which can...more Number of Targets: 0 |
| T3D3977 | Methylparaben 99-76-3 | C8H8O3 152.147 g/mol |  |
| Not Available Number of Targets: 8 |
| T3D4848 | Methyl 2-hydroxybenzoate 119-36-8 | C8H8O3 152.147 g/mol |  |
| Not Available Number of Targets: 3 |
| T3D4849 | Vanillin 121-33-5 | C8H8O3 152.147 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D4178 | N1-Methyl-2-pyridone-5-carboxamide 701-44-0 | C7H8N2O2 152.151 g/mol |  |
| Uremic toxins such as N-methyl-2-pyridone-5-carboxamide are actively transported into the kidneys via organic ion transporters (especially OAT3). Increased levels of u...more Number of Targets: 3 |
| T3D4179 | N1-Methyl-4-pyridone-3-carboxamide 769-49-3 | C7H8N2O2 152.151 g/mol |  |
| Uremic toxins such as N-methyl-4-pyridone-3-carboxamide are actively transported into the kidneys via organic ion transporters (especially OAT3). Increased levels of u...more Number of Targets: 3 |
| T3D0618 | Acenaphthylene 208-96-8 | C12H8 152.192 g/mol |  |
| The ability of PAH's to bind to blood proteins such as albumin allows them to be transported throughout the body. Many PAH's induce the expression of cytochrome P450 e...more Number of Targets: 4 |
| T3D4866 | cis-Citral 5392-40-5 | C10H16O 152.233 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D1269 | Tin(II) hydroxide 12026-24-3 | H2O2Sn 152.720 g/mol |  |
| Inorganic and organic tin compounds are weak inhibitors of alcohol dehydrogenase. (A183) Number of Targets: 7 |