Browsing Toxins
Displaying toxin 651 - 675 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D1271 | Tin(II) oxide 21651-19-4 | OSn 134.710 g/mol |  |
| Inorganic and organic tin compounds are weak inhibitors of alcohol dehydrogenase. (A183) Number of Targets: 7 |
| T3D4279 | Adenine 73-24-5 | C5H5N5 135.127 g/mol |  |
| Adenine forms adenosine, a nucleoside, when attached to ribose, and deoxyadenosine when attached to deoxyribose, and it forms adenosine triphosphate (ATP), a nucleotid...more Number of Targets: 10 |
| T3D4161 | Homocysteine 454-29-5 | C4H9NO2S 135.185 g/mol |  |
| Nitrosylation converts homocysteine (Hcy) into a methionine analogue, S-nitroso-Homocysteine, which can substitute for methionine in protein synthesis in biological sy...more Number of Targets: 5 |
| T3D0781 | Phenyl isothiocyanate 103-72-0 | C7H5NS 135.186 g/mol |  |
| Cyanide is an inhibitor of cytochrome c oxidase in the fourth complex of the electron transport chain (found in the membrane of the mitochondria of eukaryotic cells). ...more Number of Targets: 39 |
| T3D2706 | Amphetamine 300-62-9 | C9H13N 135.206 g/mol |  |
| Amphetamines stimulate the release of norepinephrine from central adrenergic receptors. At higher dosages, they cause release of dopamine from the mesocorticolimbic sy...more Number of Targets: 14 |
| T3D3051 | Dextroamphetamine 51-64-9 | C9H13N 135.206 g/mol |  |
| The exact mechanism of action is not known. Dextroamphetamine stimulates the release of norepinephrine from central adrenergic receptors. At higher dosages, it causes ...more Number of Targets: 6 |
| T3D1390 | Cobalt(II) carbonate hydroxide (2:3) 12602-23-2 | CHCoO4 135.949 g/mol |  |
| Cobalt is believed to exhibit its toxicity through a oxidant-based and free radical-based processes. It produces oxygen radicals and may be oxidized to ionic cobalt, c...more Number of Targets: 35 |
| T3D0318 | Trimethylarsine oxide 4964-14-1 | C3H9AsO 136.025 g/mol |  |
| Arsenic and its metabolites disrupt ATP production through several mechanisms. At the level of the citric acid cycle, arsenic inhibits pyruvate dehydrogenase and by co...more Number of Targets: 44 |
| T3D3477 | Allopurinol 315-30-0 | C5H4N4O 136.112 g/mol |  |
| Allopurinol inhibits the enzyme xanthine oxidase, blocking the conversion of the oxypurines hypoxanthine and xanthine to uric acid. Elevated concentrations of oxypurin...more Number of Targets: 1 |
| T3D4150 | Hypoxanthine 68-94-0 | C5H4N4O 136.112 g/mol |  |
| Hypoxanthine is a poorly soluble compound. As a result high concentrations of serum hypoxanthine can lead to the formation of kidney stones which can, over the long t...more Number of Targets: 4 |
| T3D4153 | Phenylacetic acid 103-82-2 | C8H8O2 136.148 g/mol |  |
| Uremic toxins such as phenylacetic acid are actively transported into the kidneys via organic ion transporters (especially OAT3). Increased levels of uremic toxins can...more Number of Targets: 5 |
| T3D3945 | 2-Isopropylphenol 88-69-7 | C9H12O 136.191 g/mol |  |
| Not Available Number of Targets: 2 |
| T3D1713 | Tetramethylsuccinonitrile 3333-52-6 | C8H12N2 136.194 g/mol |  |
| Organic nitriles decompose into cyanide ions both in vivo and in vitro. Consequently the primary mechanism of toxicity for organic nitriles is their production of toxi...more Number of Targets: 39 |
| T3D2889 | Phenelzine 51-71-8 | C8H12N2 136.194 g/mol |  |
| Although the exact mechanism of action has not been determined, it appears that the irreversible, nonselective inhibition of MAO by phenelzine relieves depressive symp...more Number of Targets: 11 |
| T3D3204 | 7-Methyl-3-methylene-1,6-octadiene 123-35-3 | C10H16 136.234 g/mol |  |
| Myrcene exhibits tyrosinase inhibitory activities, which plays an important role in neuromelanin formation (A2448). Number of Targets: 1 |
| T3D4890 | Gamma-terpinene 99-85-4 | C10H16 136.234 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D4927 | Terpinolene 586-62-9 | C10H16 136.234 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D4930 | (-)-alpha-Pinene 7785-26-4 | C10H16 136.234 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D0726 | Zinc chloride 7646-85-7 | Cl2Zn 136.315 g/mol |  |
| Anaemia results from the excessive absorption of zinc suppressing copper and iron absorption, most likely through competitive binding of intestinal mucosal cells. Unba...more Number of Targets: 2 |
| T3D0649 | Beryllium telluride 12232-27-8 | BeTe 136.600 g/mol |  |
| Once in the body, beryllium acts as a hapten and interacts with human leucocyte antigen (HLA) DP presenting cells in the lungs, becoming physically associated with a m...more Number of Targets: 3 |
| T3D1813 | Bromine trifluoride 7787-71-5 | BrF3 136.899 g/mol |  |
| Bromine is a powerful oxidizing agent and is able to release oxygen free radicals from the water in mucous membranes. These free radicals are also potent oxidizers and...more Number of Targets: 6 |
| T3D0213 | Cesium-137 10045-97-3 | Cs 136.907 g/mol |  |
| Highly penetrating gamma rays are the major cause of damage to tissues and internal organs following external overexposure to radioactive cesium. Once radioactive cesi...more Number of Targets: 1 |
| T3D1153 | Ammonium permanganate 13446-10-1 | H4MnNO4 136.974 g/mol |  |
| Manganese is a cellular toxicant that can impair transport systems, enzyme activities, and receptor functions. It primarily targets the central nervous system, particu...more Number of Targets: 5 |
| T3D1778 | Bromoacetone 598-31-2 | C3H5BrO 136.975 g/mol |  |
| Organobromide compounds such as bromoacetone are strong alkylating agents. Consequently they can readily modify free thiols (cysteines) and methionine residues of the...more Number of Targets: 1 |
| T3D1772 | 2-Bromobutane 78-76-2 | C4H9Br 137.018 g/mol |  |
| Bromine is a powerful oxidizing agent and is able to release oxygen free radicals from the water in mucous membranes. These free radicals are also potent oxidizers and...more Number of Targets: 0 |