Browsing Toxins
Displaying toxin 551 - 575 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D1629 | Vanadium(II) chloride 10580-52-6 | Cl2V 121.848 g/mol |  |
| Vanadium damages alveolar macrophages by decreasing the macrophage membrane integrity, thus impairing the cells' phagocytotic ability and viability. The pentavalent fo...more Number of Targets: 47 |
| T3D1646 | Sodium metavanadate 13718-26-8 | NaO3V 121.930 g/mol |  |
| Vanadium damages alveolar macrophages by decreasing the macrophage membrane integrity, thus impairing the cells' phagocytotic ability and viability. The pentavalent fo...more Number of Targets: 47 |
| T3D1519 | Aluminium phosphate 7784-30-7 | AlO4P 121.953 g/mol |  |
| The main target organs of aluminum are the central nervous system and bone. Aluminum binds with dietary phosphorus and impairs gastrointestinal absorption of phosphoru...more Number of Targets: 3 |
| T3D3561 | Guanidine nitrate 506-93-4 | CH6N4O3 122.083 g/mol |  |
| Nitrate's toxicity is a result of it's conversion to nitrite once in the body. Nitrite causes the autocatalytic oxidation of oxyhemoglobin to hydrogen peroxide and met...more Number of Targets: 9 |
| T3D4785 | Benzoic acid 65-85-0 | C7H6O2 122.121 g/mol |  |
| Not Available Number of Targets: 5 |
| T3D4892 | 2-Hydroxybenzaldehyde 90-02-8 | C7H6O2 122.121 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D4168 | Niacinamide 98-92-0 | C6H6N2O 122.125 g/mol |  |
| Uremic toxins such as nicotinamide are actively transported into the kidneys via organic ion transporters (especially OAT3). Increased levels of uremic toxins can stim...more Number of Targets: 10 |
| T3D3201 | 4-Ethylphenol 123-07-9 | C8H10O 122.164 g/mol |  |
| Metabolized to 1- and 2- phenylethanol (A622). Number of Targets: 2 |
| T3D4826 | 3,4-Dimethylphenol 95-65-8 | C8H10O 122.164 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D4867 | 2,6-Dimethylphenol 576-26-1 | C8H10O 122.164 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D4941 | 3-Ethylphenol 620-17-7 | C8H10O 122.164 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D4669 | 2,4-Toluenediamine 95-80-7 | C7H10N2 122.168 g/mol |  |
| Not Available Number of Targets: 2 |
| T3D1578 | Palladium(II) oxide 1314-08-5 | OPd 122.420 g/mol |  |
| Due to their ability to form strong complexes with both inorganic and organic ligands, palladium ions can disturb cellular equilibria, replace other essential ions, an...more Number of Targets: 6 |
| T3D1915 | Sodium perchlorate 7601-89-0 | ClNaO4 122.440 g/mol |  |
| The primary and most sensitive target of the perchlorate anion (perchlorate) is the thyroid gland. Perchlorate inhibits the transport of iodide (I-) from the blood int...more Number of Targets: 12 |
| T3D1265 | Stannane 2406-52-2 | H4Sn 122.740 g/mol |  |
| Inorganic and organic tin compounds are weak inhibitors of alcohol dehydrogenase. (A183) Number of Targets: 7 |
| T3D1436 | Chromium(II) chloride 10049-05-5 | Cl2Cr 122.902 g/mol |  |
| Trivalent chromium may also form complexes with peptides, proteins, and DNA, resulting in DNA-protein crosslinks, DNA strand breaks, DNA-DNA interstrand crosslinks, ch...more Number of Targets: 5 |
| T3D1788 | 2-Bromopropane 75-26-3 | C3H7Br 122.992 g/mol |  |
| Organobromide compounds, especially alkylbromides are strong alkylating agents. Consequently they can randomly modify the surfaces of proteins and lipids, leading to ...more Number of Targets: 3 |
| T3D1802 | 1-Bromopropane 106-94-5 | C3H7Br 122.992 g/mol |  |
| Organobromide compounds, especially alkylbromides are strong alkylating agents. Consequently they can randomly modify the surfaces of proteins and lipids, leading to ...more Number of Targets: 4 |
| T3D2841 | Nicotinic acid 59-67-6 | C6H5NO2 123.109 g/mol |  |
| Niacin binds to Nicotinate D-ribonucleotide phyrophsopate phosphoribosyltransferase, Nicotinic acid phosphoribosyltransferase, Nicotinate N-methyltransferase and the N...more Number of Targets: 4 |
| T3D4216 | Nitrobenzene 98-95-3 | C6H5NO2 123.109 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D4986 | p-Anisidine 104-94-9 | C7H9NO 123.153 g/mol |  |
| p-Anisidine reacts with secondary oxidation products such as aldehydes and ketones in fats and oils. (Wikipedia) Number of Targets: 0 |
| T3D0748 | Diethylzinc 557-20-0 | C4H10Zn 123.531 g/mol |  |
| Anaemia results from the excessive absorption of zinc suppressing copper and iron absorption, most likely through competitive binding of intestinal mucosal cells. Unba...more Number of Targets: 1 |
| T3D1208 | Copper(II) carbonate 1184-64-1 | CCuO3 123.555 g/mol |  |
| Excess copper is sequestered within hepatocyte lysosomes, where it is complexed with metallothionein. Copper hepatotoxicity is believed to occur when the lysosomes bec...more Number of Targets: 6 |
| T3D1622 | Silver(I,III) oxide 1301-96-8 | AgO 123.868 g/mol |  |
| Metallic silver is oxidized and may deposit in the tissues, causing arygria. The silver ion is known to inhibit glutathione peroxidase and NA+,K+-ATPase activity, disr...more Number of Targets: 17 |
| T3D0019 | White Phosphorus 12185-10-3 | P4 123.895 g/mol |  |
| Exposure to white phosphorus has been shown to damage the rough endoplasmic reticulum and cause a disaggregation of polyribosomes. This damage results in impairment of...more Number of Targets: 0 |