Browsing Toxins
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D2508 | Chlorotoxin 163515-35-3 | Not Available 4004.725 g/mol |  |
| Chlorotoxin blocks small conductance chloride channels. (L1043) Number of Targets: 15 |
| T3D2509 | Cobatoxin 211688-17-4 | Not Available 7131.365 g/mol |  |
| Cobatoxin blocks calcium-activated and voltage-gated potassium channels. (L1045) Number of Targets: 7 |
| T3D2510 | alpha-Cobratoxin 769933-79-1 | Not Available 7830.960 g/mol |  |
| alpha-Cobratoxin is a muscle-type nicotinic acetylcholine receptor (nAChR) antagonist. It causes paralysis by preventing the binding of acetylcholine to the nAChR, as ...more Number of Targets: 6 |
| T3D2511 | kappa-Hefutoxin 478621-50-0 | Not Available 2659.865 g/mol |  |
| kappa-Hefutoxin blocks voltage-gated potassium channels and also slows down their activation kinetics. (L1048) Number of Targets: 2 |
| T3D2513 | Imperatoxin-A 172451-37-5 | Not Available 3764.370 g/mol |  |
| Imperatoxin-A is an activator which enhances the influx of Ca2+ from the sarcoplasmatic reticulum into the cell. Imperatoxin-A acts on the Ryanodine receptors (RyR), w...more Number of Targets: 3 |
| T3D2514 | Imperatoxin-1 Not Available | Not Available 18663.670 g/mol |  |
| Imperatoxin-I is an inhibitor which decreases the influx of Ca2+ from the sarcoplasmatic reticulum into the cell. Imperatoxin-I acts on the Ryanodine receptors (RyR), ...more Number of Targets: 3 |
| T3D2515 | Kaliotoxin 145199-73-1 | Not Available 6461.905 g/mol |  |
| Kaliotoxin is a neurotoxin that binds to voltage-gated and calcium-activated potassium channels. It binds to the extracellular surface and blocks the channel, affectin...more Number of Targets: 6 |
| T3D2516 | Kaliotoxin-1 150769-72-5 | Not Available 4155.975 g/mol |  |
| Kaliotoxin is a neurotoxin that binds to voltage-gated and calcium-activated potassium channels. It binds to the extracellular surface and blocks the channel, affectin...more Number of Targets: 6 |
| T3D2517 | Kaliotoxin-2 159605-22-8 | Not Available 6392.840 g/mol | |
| Kaliotoxin is a neurotoxin that binds to voltage-gated and calcium-activated potassium channels. It binds to the extracellular surface and blocks the channel, affectin...more Number of Targets: 6 |
| T3D2518 | Kaliotoxin-3 223246-26-2 | Not Available 4027.840 g/mol | |
| Kaliotoxin is a neurotoxin that binds to voltage-gated and calcium-activated potassium channels. It binds to the extracellular surface and blocks the channel, affectin...more Number of Targets: 6 |
| T3D2519 | Kurtoxin 820959-57-7 | Not Available 7394.400 g/mol |  |
| Kurtoxin affects the gating of voltage-gated sodium channels and calcium channels. In calcium channels Kurtoxin binds close to the channel voltage sensor and thereby p...more Number of Targets: 14 |
| T3D2520 | Margatoxin 145808-47-5 | Not Available 4184.990 g/mol |  |
| Margatoxin blocks potassium channels, resulting in a loss of outward current and affecting neurotransmitter release. (L1057) Number of Targets: 1 |
| T3D2521 | Maurotoxin 188240-41-7 | Not Available 3621.205 g/mol |  |
| Maurotoxin acts by blocking several types of voltage-gated potassium channel. (L1059) Number of Targets: 7 |
| T3D2522 | Noxiustoxin 85205-49-8 | Not Available 4201.920 g/mol |  |
| Noxiustoxin blocks voltage-gated non-inactivating potassium channels and unblocks inactivating potassium channels blocked by alpha-dendrotoxin in synaptosomes. It also...more Number of Targets: 23 |
| T3D2523 | Scyllatoxin 142948-19-4 | Not Available 3430.130 g/mol |  |
| Scyllatoxin blocks small conductance calcium-activated potassium channels. This inhibits the slow after-hyperpolarisation that follows an action potential in some nerv...more Number of Targets: 3 |
| T3D2525 | Tamapin 508220-81-3 | Not Available 3465.100 g/mol |  |
| Tamapin is a selective, potent, and reversible blocker of small conductance calcium-dependent potassium channels. It inhibits SK2 with the highest affinity, SK3 with a...more Number of Targets: 3 |
| T3D2526 | Tityustoxin (Tityus serrulatus ) 39465-37-7 | Not Available 6997.935 g/mol |  |
| Tityustoxin binds to voltage-dependent sodium and potassium channels. alpha-Type tityustoxin inhibits the inactivation of the activated sodium channels by binding to s...more Number of Targets: 14 |
| T3D2539 | Calciseptine 134710-25-1 | Not Available 7044.155 g/mol |  |
| Calciseptine is a specific blocker of the L-type calcium channel, and as a result also a smooth muscle relaxant and an inhibitor of cardiac contractions. (T170) Number of Targets: 8 |
| T3D2540 | Calcicludine 178037-96-2 | Not Available 6986.205 g/mol |  |
| Calcicludine inhibits high-voltage-activated calcium channels, especially of the L-type. (L1092) Number of Targets: 10 |
| T3D2541 | Cardiotoxin (Naja atra) 155808-00-7 | Not Available 8991.970 g/mol |  |
| Cardiotoxin binds to the cell membrane and depolarizes cardiomyocytes. It also shows lytic activities on many other cells, including red blood cells. It also targets t...more Number of Targets: 11 |
| T3D2542 | Crotamine 58740-15-1 | Not Available 7518.980 g/mol |  |
| Crotamine specifically modifies voltage-sensitive sodium channels, it exhibits analgesic activity and causes severe muscle necrosis by a non-enzymatic mechanism. It al...more Number of Targets: 14 |
| T3D2543 | Crotoxin 9007-40-3 | Not Available 15272.965 g/mol |  |
| Crotoxin inhibits neuromuscular transmission by presynaptically blocking acetylcholine release from the nerve termini. (T170) Number of Targets: 0 |
| T3D2544 | Convulxin 37206-04-5 | Not Available 18140.725 g/mol |  |
| Convulxin binds to the platelet and collagen receptor, glycoprotein VI (GPVI). This causes platelet activation in the blood forming clots and a build up of pressure, w...more Number of Targets: 1 |
| T3D2545 | Dendrotoxin (Dendroaspis polylepis polylepis) 119128-61-9 | Not Available 7155.305 g/mol |  |
| Dendrotoxins block particular subtypes of voltage-gated potassium channels in neurons, thereby prolonging the duration of action potentials and enhancing the release o...more Number of Targets: 23 |
| T3D2546 | Dendrotoxin (Dendroaspis angusticeps) 74504-53-3 | Not Available 3417.825 g/mol |  |
| Dendrotoxins block particular subtypes of voltage-gated potassium channels in neurons, thereby prolonging the duration of action potentials and enhancing the release o...more Number of Targets: 23 |