Browsing Toxins
Displaying toxin 301 - 325 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D1539 | Sodium aluminate 1302-42-7 | AlNaO2 81.970 g/mol |  |
| The main target organs of aluminum are the central nervous system and bone. Aluminum binds with dietary phosphorus and impairs gastrointestinal absorption of phosphoru...more Number of Targets: 3 |
| T3D1190 | Copper(I) fluoride 13478-41-6 | CuF 82.544 g/mol |  |
| Excess copper is sequestered within hepatocyte lysosomes, where it is complexed with metallothionein. Copper hepatotoxicity is believed to occur when the lysosomes bec...more Number of Targets: 6 |
| T3D1638 | Vanadium(IV) oxide 12036-21-4 | O2V 82.940 g/mol |  |
| Vanadium damages alveolar macrophages by decreasing the macrophage membrane integrity, thus impairing the cells' phagocytotic ability and viability. The pentavalent fo...more Number of Targets: 47 |
| T3D1650 | tert-Butyl isocyanide 7188-38-7 | C5H9N 83.132 g/mol |  |
| Cyanide is an inhibitor of cytochrome c oxidase in the fourth complex of the electron transport chain (found in the membrane of the mitochondria of eukaryotic cells). ...more Number of Targets: 39 |
| T3D1449 | Chromium(IV) oxide 12018-01-8 | CrO2 83.995 g/mol |  |
| Trivalent chromium may also form complexes with peptides, proteins, and DNA, resulting in DNA-protein crosslinks, DNA strand breaks, DNA-DNA interstrand crosslinks, ch...more Number of Targets: 5 |
| T3D1679 | Cyanoacetamide 107-91-5 | C3H4N2O 84.077 g/mol |  |
| Organic nitriles decompose into cyanide ions both in vivo and in vitro. Consequently the primary mechanism of toxicity for organic nitriles is their production of toxi...more Number of Targets: 40 |
| T3D3463 | 3-Methyl-2-pentene 922-62-3 | C6H12 84.160 g/mol |  |
| Petroleum distillates are central nervous system depressants and cause pulmonary damage. (A600) Number of Targets: 0 |
| T3D3466 | Methylcyclopentane 96-37-7 | C6H12 84.160 g/mol |  |
| Petroleum distillates are central nervous system depressants and cause pulmonary damage. (A600) Number of Targets: 0 |
| T3D3467 | Cyclohexane 110-82-7 | C6H12 84.160 g/mol |  |
| Petroleum distillates are central nervous system depressants and cause pulmonary damage. (A600) Number of Targets: 1 |
| T3D0080 | Dichloromethane 1975-09-02 | CH2Cl2 84.933 g/mol |  |
| Methylene chloride targets the lungs, blood system, and nervous system. In the lungs its metabolites damage Clara cells. It is also metabolized into carbon monoxide, w...more Number of Targets: 11 |
| T3D3574 | Sodium nitrate 7631-99-4 | NNaO3 84.995 g/mol |  |
| Nitrate's toxicity is a result of it's conversion to nitrite once in the body. Nitrite causes the autocatalytic oxidation of oxyhemoglobin to hydrogen peroxide and met...more Number of Targets: 11 |
| T3D1683 | Cyanoacetic acid 372-09-8 | C3H3NO2 85.061 g/mol |  |
| Organic nitriles decompose into cyanide ions both in vivo and in vitro. Consequently the primary mechanism of toxicity for organic nitriles is their production of toxi...more Number of Targets: 39 |
| T3D3550 | Potassium nitrite 7758-09-0 | KNO2 85.104 g/mol |  |
| Nitrite causes the autocatalytic oxidation of oxyhemoglobin to hydrogen peroxide and methemoglobin. This elevation of methemoglobin levels is a condition known as meth...more Number of Targets: 9 |
| T3D1678 | Acetone cyanohydrin 75-86-5 | C4H7NO 85.105 g/mol |  |
| Organic nitriles decompose into cyanide ions both in vivo and in vitro. Consequently the primary mechanism of toxicity for organic nitriles is their production of toxi...more Number of Targets: 39 |
| T3D1414 | Nickel aluminide 12003-78-0 | AlNi 85.675 g/mol |  |
| Nickel is known to substitute for other essential elements in certain enzmes, such as calcineurin. It is genotoxic, and some nickel compounds have been shown to promot...more Number of Targets: 71 |
| T3D1290 | Boron arsenide 12005-69-5 | AsB 85.733 g/mol |  |
| Arsenic and its metabolites disrupt ATP production through several mechanisms. At the level of the citric acid cycle, arsenic inhibits pyruvate dehydrogenase and by co...more Number of Targets: 44 |
| T3D2562 | Gamma-Butyrolactone 96-48-0 | C4H6O2 86.089 g/mol |  |
| Gamma-butyrolactone is rapidly converted to gamma-hydroxybutyrate. This may account for the subsequent central nervous system depressant. Gamma-butyrolactone is an ane...more Number of Targets: 1 |
| T3D3241 | Diacetyl 431-03-8 | C4H6O2 86.089 g/mol |  |
| Diacetyl is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholinestera...more Number of Targets: 4 |
| T3D3470 | Ethenyl acetate 108-05-4 | C4H6O2 86.089 g/mol |  |
| One of the metabolites of vinyl acetate, acetaldehyde, is a known animal carcinogen. Acetaldehyde can form adducts with DNA, causing damage such as cross-links. (L1304...more Number of Targets: 1 |
| T3D2403 | Hexane 110-54-3 | C6H14 86.175 g/mol |  |
| Hexane's toxicity is caused by it neurotoxic metabolite, 2,5-hexanedione. It damages the central and peripheral nervous system by causing axonal swelling and degenerat...more Number of Targets: 6 |
| T3D2404 | 2-Methylpentane 107-83-5 | C6H14 86.175 g/mol |  |
| Hexane's toxicity is caused by it neurotoxic metabolite, 2,5-hexanedione. It damages the central and peripheral nervous system by causing axonal swelling and degenerat...more Number of Targets: 4 |
| T3D2405 | 3-Methylpentane 96-14-0 | C6H14 86.175 g/mol |  |
| Hexane's toxicity is caused by it neurotoxic metabolite, 2,5-hexanedione. It damages the central and peripheral nervous system by causing axonal swelling and degenerat...more Number of Targets: 4 |
| T3D2406 | 2,3-Dimethylbutane 79-29-8 | C6H14 86.175 g/mol |  |
| Hexane's toxicity is caused by it neurotoxic metabolite, 2,5-hexanedione. It damages the central and peripheral nervous system by causing axonal swelling and degenerat...more Number of Targets: 4 |
| T3D2407 | 2,2-Dimethylbutane 75-83-2 | C6H14 86.175 g/mol |  |
| Hexane's toxicity is caused by it neurotoxic metabolite, 2,5-hexanedione. It damages the central and peripheral nervous system by causing axonal swelling and degenerat...more Number of Targets: 4 |
| T3D2412 | Iron phosphide 12023-53-9 | FeP 86.819 g/mol |  |
| Phosphine inhibits cytochrome c oxidase, preventing mitochondrial oxidative phosphorylation. This non-competitive inhibition prevents cellular respiration and leads to...more Number of Targets: 20 |