Browsing Toxins
Displaying toxin 2826 - 2850 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D4566 | Camazepam 36104-80-0 | C19H18ClN3O3 371.818 g/mol |  |
| Camazepam has been shown to bind competitively to benzodiazepine receptors in the brain with a relatively low affinity in animal models. This binding of benzodiazepine...more Number of Targets: 18 |
| T3D2852 | Trazodone 19794-93-5 | C19H22ClN5O 371.864 g/mol |  |
| Trazodone binds at 5-HT2 receptor, it acts as a serotonin agonist at high doses and a serotonin antagonist at low doses. Like fluoxetine, trazodone's antidepressant ac...more Number of Targets: 15 |
| T3D3930 | Tetraconazole 112281-77-3 | C13H11Cl2F4N3O 372.146 g/mol |  |
| Not Available Number of Targets: 15 |
| T3D1858 | Pyrethrin II 121-29-9 | C22H28O5 372.455 g/mol |  |
| Pyrethrins exert their effect by prolonging the open phase of the sodium channel gates when a nerve cell is excited. They appear to bind to the membrane lipid phase in...more Number of Targets: 21 |
| T3D0233 | Pyrethrum 8003-34-7 | C22H28O5 372.455 g/mol |  |
| Both type I and type II pyrethroids exert their effect by prolonging the open phase of the sodium channel gates when a nerve cell is excited. They appear to bind to th...more Number of Targets: 20 |
| T3D1270 | Tin(II) iodide 10294-70-9 | I2Sn 372.520 g/mol |  |
| Inorganic and organic tin compounds are weak inhibitors of alcohol dehydrogenase. (A183) Number of Targets: 7 |
| T3D4821 | Gentian Violet 14426-25-6 | C25H30N3 372.525 g/mol |  |
| Gentian Violet is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholin...more Number of Targets: 41 |
| T3D4820 | Finasteride 98319-26-7 | C23H36N2O2 372.544 g/mol |  |
| The mechanism of action of Finasteride is based on its preferential inhibition of Type II 5a-reductase through the formation of a stable complex with the enzyme. Inhib...more Number of Targets: 8 |
| T3D3919 | Quizalofop-ethyl 76578-14-8 | C19H17ClN2O4 372.802 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D0034 | Heptachlor 76-44-8 | C10H5Cl7 373.318 g/mol |  |
| Heptachlor is a central nervous system stimulant. It non-competitively blocks neurotransmitter action at gamma-amino butyric acid receptors, resulting in overstimulati...more Number of Targets: 40 |
| T3D1317 | Strontium arsenite tetrahydrate 10378-48-0 | As2H8O8Sr 373.520 g/mol |  |
| Arsenic and its metabolites disrupt ATP production through several mechanisms. At the level of the citric acid cycle, arsenic inhibits pyruvate dehydrogenase and by co...more Number of Targets: 44 |
| T3D4528 | Profenofos 41198-08-7 | C11H15BrClO3PS 373.631 g/mol |  |
| Profenofos is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholineste...more Number of Targets: 18 |
| T3D2789 | Prochlorperazine 58-38-8 | C20H24ClN3S 373.943 g/mol |  |
| The mechanism of action of prochlorperazine has not been fully determined, but may be primarily related to its antidopaminergic effects. Prochlorperazine blocks the D2...more Number of Targets: 9 |
| T3D1322 | Lead chlorate 10294-47-0 | Cl2O6Pb 374.100 g/mol |  |
| Lead mimics other biologically important metals, such as zinc, calcium, and iron, competing as cofactors for many of their respective enzymatic reactions. For example,...more Number of Targets: 29 |
| T3D4504 | Famoxadone 131807-57-3 | C22H18N2O4 374.389 g/mol |  |
| Not Available Number of Targets: 31 |
| T3D1856 | Jasmolin II 1172-63-0 | C22H30O5 374.471 g/mol |  |
| Pyrethrins exert their effect by prolonging the open phase of the sodium channel gates when a nerve cell is excited. They appear to bind to the membrane lipid phase in...more Number of Targets: 20 |
| T3D2138 | 1,2,3,4,6,7-Hexachlorodibenzofuran 79060-60-9 | C12H2Cl6O 374.862 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D2140 | 1,2,3,4,6,8-Hexachlorodibenzofuran 69698-60-8 | C12H2Cl6O 374.862 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D2141 | 1,2,3,4,6,9-Hexachlorodibenzofuran 91538-83-9 | C12H2Cl6O 374.862 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D2146 | 1,2,3,4,7,8-Hexachlorodibenzofuran 70648-26-9 | C12H2Cl6O 374.862 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D2147 | 1,2,3,4,7,9-Hexachlorodibenzofuran 91538-84-0 | C12H2Cl6O 374.862 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D2149 | 1,2,3,4,8,9-Hexachlorodibenzofuran 92341-07-6 | C12H2Cl6O 374.862 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D2155 | 2,3,4,7,8,9-Hexachlorodibenzofuran 57117-44-9 | C12H2Cl6O 374.862 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D2156 | 1,2,3,6,7,9-Hexachlorodibenzofuran 92341-06-5 | C12H2Cl6O 374.862 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D2158 | 1,2,3,6,8,9-Hexachlorodibenzofuran 75198-38-8 | C12H2Cl6O 374.862 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |