Browsing Toxins
Displaying toxin 2801 - 2825 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D3948 | Tetrachlorobisphenol A 79-95-8 | C15H12Cl4O2 366.067 g/mol |  |
| Not Available Number of Targets: 9 |
| T3D1182 | Uranyl sulfate 1314-64-3 | O6SU 366.090 g/mol |  |
| Uranium is combined with either bicarbonate or a plasma protein in the blood but once in the kidney, it is released and forms complexes with phosphate ligands and prot...more Number of Targets: 1 |
| T3D0376 | Cadmium iodide 7790-80-9 | CdI2 366.220 g/mol |  |
| Cadmium initially binds to metallothionein and is transported to the kidney. Toxic effects are observed once the concentration of cadmium exceeds that of available met...more Number of Targets: 19 |
| T3D3021 | Ridogrel 110140-89-1 | C18H17F3N2O3 366.334 g/mol |  |
| Ridogrel inhibits thromboxane A2 synthase and also blocks the thromboxane A2/prostaglandin endoperoxide receptors.
Thromboxane synthetase produces thromboxane in plate...more Number of Targets: 3 |
| T3D3705 | Diacetoxyscirpenol 2270-40-8 | C19H26O7 366.406 g/mol |  |
| Unlike many other mycotoxins, trichothecenes do not require metabolic activation to exert their biological activity, instead directly reacting with cellular components...more Number of Targets: 2 |
| T3D1557 | Tri-n-ocylaluminum 1070-00-4 | C24H51Al 366.643 g/mol |  |
| The main target organs of aluminum are the central nervous system and bone. Aluminum binds with dietary phosphorus and impairs gastrointestinal absorption of phosphoru...more Number of Targets: 3 |
| T3D0322 | Lead bromide 10031-22-8 | Br2Pb 367.000 g/mol |  |
| Lead mimics other biologically important metals, such as zinc, calcium, and iron, competing as cofactors for many of their respective enzymatic reactions. For example,...more Number of Targets: 29 |
| T3D3849 | Fluroxypyr-meptyl 81406-37-3 | C15H21Cl2FN2O3 367.243 g/mol |  |
| Not Available Number of Targets: 10 |
| T3D4073 | Bicuculline 485-49-4 | C20H17NO6 367.352 g/mol |  |
| The action of bicuculline is primarily on the ionotropic GABAA receptors, which are ligand-gated ion channels concerned chiefly with the passing of chloride ions acros...more Number of Targets: 4 |
| T3D1765 | Titanium tetrabromide 7789-68-6 | Br4Ti 367.483 g/mol |  |
| Bromine is a powerful oxidizing agent and is able to release oxygen free radicals from the water in mucous membranes. These free radicals are also potent oxidizers and...more Number of Targets: 6 |
| T3D3901 | Phosalone 2310-17-0 | C12H15ClNO4PS2 367.809 g/mol |  |
| Phosalone is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholinester...more Number of Targets: 21 |
| T3D0368 | Cadmium bromate 14518-94-6 | Br2CdO6 368.215 g/mol |  |
| Cadmium initially binds to metallothionein and is transported to the kidney. Toxic effects are observed once the concentration of cadmium exceeds that of available met...more Number of Targets: 25 |
| T3D0763 | Potassium ferrocyanide 13943-58-3 | C6FeK4N6 368.340 g/mol |  |
| Cyanide is an inhibitor of cytochrome c oxidase in the fourth complex of the electron transport chain (found in the membrane of the mitochondria of eukaryotic cells). ...more Number of Targets: 39 |
| T3D3880 | Methoxyfenozide 161050-58-4 | C22H28N2O3 368.469 g/mol |  |
| Not Available Number of Targets: 9 |
| T3D4242 | Dehydroepiandrosterone sulfate 651-48-9 | C19H28O5S 368.488 g/mol |  |
| Although it predominantly functions as an endogenous precursor to more potent androgens such as testosterone and dihydroxytestosterone, DHEA (which is produced from DH...more Number of Targets: 0 |
| T3D4571 | Ketazolam 27223-35-4 | C20H17ClN2O3 368.814 g/mol |  |
| Benzodiazepines share a similar chemical structure and their effects in humans are mainly produced by the allosteric modification of a specific kind of neurotransmitte...more Number of Targets: 18 |
| T3D3606 | Ochratoxin B 4825-86-9 | C20H19NO6 369.368 g/mol |  |
| Ochratoxin B is thought to inhibit the accumulation of cartilage proteoglycans and general protein synthesis in a concentration-related manner. (A2872) Number of Targets: 0 |
| T3D4562 | Heroin 561-27-3 | C21H23NO5 369.411 g/mol |  |
| Heroin is a mu-opioid agonist. It acts on endogenous mu-opioid receptors that are spread in discrete packets throughout the brain, spinal cord and gut in almost all ma...more Number of Targets: 4 |
| T3D3000 | Trimetrexate 52128-35-5 | C19H23N5O3 369.418 g/mol |  |
| In vitro studies have shown that trimetrexate is a competitive inhibitor of dihydrofolate reductase (DHFR) from bacterial, protozoan, and mammalian sources. DHFR catal...more Number of Targets: 2 |
| T3D1252 | Hydroxytriphenylstannane 76-87-9 | C18H19OSn 370.050 g/mol |  |
| Organotin compounds produce neurotoxic and immunotoxic effects. Organotins may directly activate glial cells contributing to neuronal cell degeneration by local releas...more Number of Targets: 45 |
| T3D3092 | Grayanotoxin III 4678-45-9 | C20H34O6 370.480 g/mol |  |
| Grayanotoxins bind to specific sodium ion channels in cell membranes. The grayanotoxins prevent inactivation, leaving excitable cells depolarized. (L1251) Number of Targets: 14 |
| T3D0144 | Dicofol 115-32-2 | C14H9Cl5O 370.486 g/mol |  |
| Like other organochloride pesticides, dicofol is believed to act by at least four mechanisms, possibly all functioning simultaneously. It may reduce potassium transpor...more Number of Targets: 74 |
| T3D2858 | Thioridazine 50-52-2 | C21H26N2S2 370.575 g/mol |  |
| Thioridazine blocks postsynaptic mesolimbic dopaminergic D1 and D2 receptors in the brain; blocks alpha-adrenergic effect, depresses the release of hypothalamic and hy...more Number of Targets: 15 |
| T3D4714 | Tamoxifen 10540-29-1 | C26H29NO 371.515 g/mol |  |
| Tamoxifen is a nonsteroidal agent that binds to estrogen receptors (ER), inducing a conformational change in the receptor. This results in a blockage or change in the ...more Number of Targets: 12 |
| T3D1867 | Diantimony tetrasulfide 12359-48-7 | S4Sb2 371.780 g/mol |  |
| The inhalation data suggests that the myocardium is a target of antimony toxicity. It is possible that antimony affects circulating glucose by interfering with enzymes...more Number of Targets: 20 |