Browsing Toxins
Displaying toxin 2776 - 2800 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D1722 | Antimony tribromide 7789-61-9 | Br3Sb 361.470 g/mol |  |
| Bromine is a powerful oxidizing agent and is able to release oxygen free radicals from the water in mucous membranes. These free radicals are also potent oxidizers and...more Number of Targets: 26 |
| T3D3790 | Acifluorfen 50594-66-6 | C14H7ClF3NO5 361.657 g/mol |  |
| Not Available Number of Targets: 10 |
| T3D1217 | Copper(II) triflate 34946-82-2 | C2CuF6O6S2 361.684 g/mol |  |
| Excess copper is sequestered within hepatocyte lysosomes, where it is complexed with metallothionein. Copper hepatotoxicity is believed to occur when the lysosomes bec...more Number of Targets: 6 |
| T3D3896 | Oxyfluorfen 42874-03-3 | C15H11ClF3NO4 361.700 g/mol |  |
| Not Available Number of Targets: 14 |
| T3D4507 | Fenoxaprop-ethyl 66441-23-4 | C18H16ClNO5 361.776 g/mol |  |
| ACCLAIM is a proprietary combination of nitrate and L-arginine that provides the beneficial cardiovascular effects of nitrates. Combining L-arginine with organic nitra...more Number of Targets: 7 |
| T3D1572 | Allylpalladium chloride dimer 12012-95-2 | C6H6Cl2Pd2 361.860 g/mol |  |
| Due to their ability to form strong complexes with both inorganic and organic ligands, palladium ions can disturb cellular equilibria, replace other essential ions, an...more Number of Targets: 6 |
| T3D1460 | Zinc diethyldithiocarbamate 14324-55-1 | C10H20N2S4Zn 361.948 g/mol |  |
| Anaemia results from the excessive absorption of zinc suppressing copper and iron absorption, most likely through competitive binding of intestinal mucosal cells. Unba...more Number of Targets: 1 |
| T3D1180 | Uranyl formate 16984-59-1 | C2H4O6U 362.079 g/mol |  |
| Uranium is combined with either bicarbonate or a plasma protein in the blood but once in the kidney, it is released and forms complexes with phosphate ligands and prot...more Number of Targets: 1 |
| T3D0388 | Cadmium tungstate 7790-85-4 | CdH2O4W 362.260 g/mol |  |
| Cadmium initially binds to metallothionein and is transported to the kidney. Toxic effects are observed once the concentration of cadmium exceeds that of available met...more Number of Targets: 19 |
| T3D3036 | Fosphenytoin 93390-81-9 | C16H15N2O6P 362.274 g/mol |  |
| Fosphenytoin is a prodrug of phenytoin and accordingly, its anticonvulsant effects are attributable to phenytoin. Phenytoin acts on sodium channels on the neuronal cel...more Number of Targets: 1 |
| T3D4284 | 18-Hydroxycorticosterone 561-65-9 | C21H30O5 362.460 g/mol |  |
| 18-Hydroxycorticosterone is a derivative of corticosterone. It serves as an intermediate in the synthesis of aldosterone by the enzyme aldosterone synthase in the zona...more Number of Targets: 1 |
| T3D3640 | Butyl decyl phthalate 89-19-0 | C22H34O4 362.503 g/mol |  |
| Phthalate esters are endocrine disruptors. They decrease foetal testis testosterone production and reduce the expression of steroidogenic genes by decreasing mRNA expr...more Number of Targets: 0 |
| T3D3646 | Diisoheptyl phthalate 41451-28-9 | C22H34O4 362.503 g/mol |  |
| Phthalate esters are endocrine disruptors. They decrease foetal testis testosterone production and reduce the expression of steroidogenic genes by decreasing mRNA expr...more Number of Targets: 0 |
| T3D4489 | Coumaphos 56-72-4 | C14H16ClO5PS 362.766 g/mol |  |
| Coumaphos is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholinester...more Number of Targets: 36 |
| T3D4649 | Mexazolam 31868-18-5 | C18H16Cl2N2O2 363.238 g/mol |  |
| Benzodiazepines bind nonspecifically to benzodiazepine receptors BNZ1, which mediates sleep, and BNZ2, which affects affects muscle relaxation, anticonvulsant activity...more Number of Targets: 18 |
| T3D3843 | Flufenacet 142459-58-3 | C14H13F4N3O2S 363.331 g/mol |  |
| Not Available Number of Targets: 6 |
| T3D1473 | Zinc trifluoromethanesulfonate 54010-75-2 | C2F6O6S2Zn 363.547 g/mol |  |
| Anaemia results from the excessive absorption of zinc suppressing copper and iron absorption, most likely through competitive binding of intestinal mucosal cells. Unba...more Number of Targets: 1 |
| T3D4069 | Phorbol 17673-25-5 | C20H28O6 364.433 g/mol |  |
| The term 'phorbol' is used to describe the family of naturally occurring compounds that can be referred to as tigliane diterpenes. Phorbol esters are the tetracyclic d...more Number of Targets: 0 |
| T3D3063 | Quinestrol 152-43-2 | C25H32O2 364.520 g/mol |  |
| Estrogens diffuse into their target cells and interact with a protein receptor (the estrogen receptor). Estrogen interacts with a target cell receptor. When the estrog...more Number of Targets: 1 |
| T3D1023 | Isodrin 465-73-6 | C12H8Cl6 364.910 g/mol |  |
| It antagonizes the action of the neurotransmitter gamma-aminobutyric acid (GABA) acting at the GABA-A receptors, effectively blocking the GABA-induced uptake of chlori...more Number of Targets: 38 |
| T3D0024 | Aldrin 309-00-2 | C12H8Cl6 364.910 g/mol |  |
| Aldrin antagonizes the action of the neurotransmitter gamma-aminobutyric acid (GABA) acting at the GABA-A receptors, effectively blocking the GABA-induced uptake of ch...more Number of Targets: 41 |
| T3D3915 | Pyridaben 96489-71-3 | C19H25ClN2OS 364.933 g/mol |  |
| Not Available Number of Targets: 28 |
| T3D4736 | Fludarabine 75607-67-9 | C10H13FN5O7P 365.212 g/mol |  |
| Fludarabine phosphate is rapidly dephosphorylated to 2-fluoro-ara-A and then phosphorylated intracellularly by deoxycytidine kinase to the active triphosphate, 2-fluor...more Number of Targets: 4 |
| T3D1805 | Tribromoisocyanuric acid 17497-85-7 | C3Br3N3O3 365.762 g/mol |  |
| Bromine is a powerful oxidizing agent and is able to release oxygen free radicals from the water in mucous membranes. These free radicals are also potent oxidizers and...more Number of Targets: 0 |
| T3D1411 | Nickel phosphate 14396-43-1 | Ni3O8P2 366.023 g/mol |  |
| Nickel is known to substitute for other essential elements in certain enzmes, such as calcineurin. It is genotoxic, and some nickel compounds have been shown to promot...more Number of Targets: 68 |